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Erschienen in: Irish Journal of Medical Science (1971 -) 1/2016

01.02.2016 | Review Article

Therapeutic goals in patients with pheochromocytoma: a guide to perioperative management

verfasst von: N. Azadeh, H. Ramakrishna, N. L. Bhatia, J. C. Charles, F. Mookadam

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 1/2016

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Abstract

Introduction

Pheochromocytomas are rare neuroendocrine tumors of the adrenal medulla that may present with protean manifestations. Surgical resection is the mainstay of therapy and patients are at risk of significant hemodynamic and circulatory complications mainly attributable to catecholamine excess. The mainstay of medical therapy in order to optimize patients for surgery includes: alpha-blockers, beta-blockers, calcium channel blocker and other agents to achieve normal blood pressure, heart rate, as well as normal volume status. Understanding the pathophysiology of pheochromocytoma, the pharmacology of medications used, and recognizing postoperative complications will impact patient outcomes.

Conclusion

A multidisciplinary team approach is best throughout the perioperative period to prevent potential complications that arise. The hospital physician, intensivist, anesthetist and cardiovascular specialist play a pivotal role in the management of patients with pheochromocytoma. In addition to the pharmacologic and volume recommendations, a multidisciplinary discussion allows for seamless implementation of an organized plan of care.
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Metadaten
Titel
Therapeutic goals in patients with pheochromocytoma: a guide to perioperative management
verfasst von
N. Azadeh
H. Ramakrishna
N. L. Bhatia
J. C. Charles
F. Mookadam
Publikationsdatum
01.02.2016
Verlag
Springer London
Erschienen in
Irish Journal of Medical Science (1971 -) / Ausgabe 1/2016
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-015-1383-5

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