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Erschienen in: Lung 1/2019

29.10.2018 | LUNG IMAGES

Thoracic Air-Leak Syndrome Complicating Allogeneic Hematopoietic Stem-Cell Transplantation

verfasst von: Tiara Boghanim, Marlène Murris, Tatiana Lamon, Anne Huynh, Julien Mazières, Charles-Hugo Marquette, Alain Didier

Erschienen in: Lung | Ausgabe 1/2019

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Abstract

We report a case of thoracic air-leak syndrome, an extremely rare complication developed after an episode of organizing pneumonia due to graft-vs-host disease in a 19-year-old male. This unusual non-infectious pulmonary complication occurred 527 days after allogeneic HSCT and led to the patient’s death within 1 month due to cardio-respiratory failure. Herein, we highlight chest-imaging aspects which are typical. Early detection by high-resolution chest CT could improve patient management.
Literatur
1.
Zurück zum Zitat Franquet T, Giménez A, Torrubia S, Sabaté JM, Rodriguez-Arias JM (2000) Spontaneous pneumothorax and pneumomediastinum in IPF. Eur Radiol 10(1):108–113CrossRefPubMed Franquet T, Giménez A, Torrubia S, Sabaté JM, Rodriguez-Arias JM (2000) Spontaneous pneumothorax and pneumomediastinum in IPF. Eur Radiol 10(1):108–113CrossRefPubMed
2.
Zurück zum Zitat Moon MH, Sa YJ, Cho KD, Jo KH, Lee SH, Sim SB (2010) Thoracic air-leak syndromes in hematopoietic stem cell transplant recipients with graft-versus-host disease: a possible sign for poor response to treatment and poor prognosis. J Korean Med Sci 25(5):658–662CrossRefPubMedPubMedCentral Moon MH, Sa YJ, Cho KD, Jo KH, Lee SH, Sim SB (2010) Thoracic air-leak syndromes in hematopoietic stem cell transplant recipients with graft-versus-host disease: a possible sign for poor response to treatment and poor prognosis. J Korean Med Sci 25(5):658–662CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Vogel M, Brodoefel H, Bethge W, Faul C, Hartmann J, Schimmel H et al (2006) Spontaneous thoracic air-leakage syndrome in patients following allogeneic hematopoietic stem cell transplantation: causes, CT-follow up and patient outcome. Eur J Radiol 60(3):392–397CrossRefPubMed Vogel M, Brodoefel H, Bethge W, Faul C, Hartmann J, Schimmel H et al (2006) Spontaneous thoracic air-leakage syndrome in patients following allogeneic hematopoietic stem cell transplantation: causes, CT-follow up and patient outcome. Eur J Radiol 60(3):392–397CrossRefPubMed
4.
Zurück zum Zitat Toubai T, Tanaka J, Kobayashi N, Honda T, Miura Y, Ogawa T et al (2004) Mediastinal emphysema and bilateral pneumothoraces with chronic GVHD in patients after allogeneic stem cell transplantation. Bone Marrow Transplant 33(11):1159–1163CrossRefPubMed Toubai T, Tanaka J, Kobayashi N, Honda T, Miura Y, Ogawa T et al (2004) Mediastinal emphysema and bilateral pneumothoraces with chronic GVHD in patients after allogeneic stem cell transplantation. Bone Marrow Transplant 33(11):1159–1163CrossRefPubMed
5.
Zurück zum Zitat Sakai R, Kanamori H, Nakaseko C, Yoshiba F, Fujimaki K, Sakura T et al (2011) Air-leak syndrome following allo-SCT in adult patients: report from the Kanto Study Group for Cell Therapy in Japan. Bone Marrow Transplant 46(3):379–384CrossRefPubMed Sakai R, Kanamori H, Nakaseko C, Yoshiba F, Fujimaki K, Sakura T et al (2011) Air-leak syndrome following allo-SCT in adult patients: report from the Kanto Study Group for Cell Therapy in Japan. Bone Marrow Transplant 46(3):379–384CrossRefPubMed
6.
Zurück zum Zitat Bergeron A (2017) Late-onset noninfectious pulmonary complications after allogeneic hematopoietic stem cell transplantation. Clin Chest Med 38(2):249–262CrossRefPubMed Bergeron A (2017) Late-onset noninfectious pulmonary complications after allogeneic hematopoietic stem cell transplantation. Clin Chest Med 38(2):249–262CrossRefPubMed
Metadaten
Titel
Thoracic Air-Leak Syndrome Complicating Allogeneic Hematopoietic Stem-Cell Transplantation
verfasst von
Tiara Boghanim
Marlène Murris
Tatiana Lamon
Anne Huynh
Julien Mazières
Charles-Hugo Marquette
Alain Didier
Publikationsdatum
29.10.2018
Verlag
Springer US
Erschienen in
Lung / Ausgabe 1/2019
Print ISSN: 0341-2040
Elektronische ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-018-0173-z

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