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01.12.2018 | Research article | Ausgabe 1/2018 Open Access

BMC Cardiovascular Disorders 1/2018

Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology

Zeitschrift:
BMC Cardiovascular Disorders > Ausgabe 1/2018
Autoren:
Hélder Pereira, Daniel Caldeira, Rui Campante Teles, Marco Costa, Pedro Canas da Silva, Vasco da Gama Ribeiro, Vítor Brandão, Dinis Martins, Fernando Matias, Francisco Pereira-Machado, José Baptista, Pedro Farto e Abreu, Ricardo Santos, António Drummond, Henrique Cyrne de Carvalho, João Calisto, João Carlos Silva, João Luís Pipa, Jorge Marques, Paulino Sousa, Renato Fernandes, Rui Cruz Ferreira, Sousa Ramos, Eduardo Infante Oliveira, Manuel de Sousa Almeida, on behalf of the investigators of Portuguese Registry on Interventional Cardiology (Registo Nacional de Cardiologia de Intervenção)

Abstract

Background

We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in ‘real-world’ settings.

Methods

We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006–2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI).

Results

We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54–1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35–0.98; 3500 patients).

Conclusions

The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.
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