Skip to main content
main-content

09.01.2020 | Review

Thyroid eye disease: current and potential medical management

Zeitschrift:
International Ophthalmology
Autoren:
Jessica M. Pouso-Diz, Jose M. Abalo-Lojo, Francisco Gonzalez
Wichtige Hinweise

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Introduction

Thyroid eye disease (TED) is the most frequent extra-thyroid manifestation of Graves’ disease and it is more frequent in middle age and in female gender. Nowadays, the causal mechanisms of this disease are not completely understood, but the current available studies suggest that the main causative factor is the thyroid stimulating hormone receptor.

Materials and methods

To collect reports on TED medical management, a thorough literature search was performed in PubMed database. An additional search was made in Google Scholar to complete the collected items.

Results

Among the indentified risk factors, tobacco habit is the most relevant. The main criteria to choose a suitable treatment are the activity and severity of the disease. Support measures can be used to improve the patient’s symptoms in any phase of the disease. There is a large number of drugs proposed to manage TED, although with different reported rates of success.

Conclusions

Currently, the drugs of choice are corticosteroids in moderate-to-severe and in sight-threatening forms. The main problem of corticosteroids is their spectrum of side effects. Therefore, other alternatives are being suggested for medical management of this disease. The efficacy of these alternatives remains unclear.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Jetzt e.Med bestellen und 100 € sparen!

Literatur
Über diesen Artikel

Neu im Fachgebiet Augenheilkunde

29.01.2020 | DFP-Fortbildung | Ausgabe 1/2020

„White-dot-Syndrome“

Grundlagen, Diagnostik und Therapie

08.01.2020 | Erkrankungen der Hornhaut | CME | Ausgabe 1/2020

Anteriore virale Uveitis

Klinik, diagnostisches Vorgehen und Behandlungsoptionen