Thyroid function post-bariatric surgery: an updated systematic review and meta-analysis
- 26.11.2025
- Review
Erschienen in:
- Verfasst von
- Niloofar Seighali
- Alireza Khodayari Javazm
- Sina Kazemian
- Mohammadhasan Matin
- Hedie Soltani
- Mahya Beikmohammdi
- Amirhossein Mehrpour
- Mahmood Bakhtiyari
- Erschienen in
- Obesity Surgery | Ausgabe 12/2025
Abstract
This systematic review and meta-analysis aim to comprehensively assess the effect of bariatric surgery on thyroid function. A search of PubMed, Web of Science, and Scopus databases was performed until 19 November 2024. Sixty-seven studies with 8,754 total patients included in our analysis showed a significant decrease in pooled standard mean differences (SMD) of serum TSH, total T3, and free T3 levels post operation (p-value < 0.05). Our analysis showed a significant marginal decrease in total T4 level by subgroup analysis in overall region and surgery (p-value < 0.05) whereas free T4 didn’t change significantly (p-value > 0.05). Subgroup analyses, meta-regression, and publication bias analysis were done. Based on this meta-analysis, significant reduction of TSH, marginally total T4, Total T3, and free T3 levels, as well as non-significant change of FT4 are expected following bariatric surgery.
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- Titel
- Thyroid function post-bariatric surgery: an updated systematic review and meta-analysis
- Verfasst von
-
Niloofar Seighali
Alireza Khodayari Javazm
Sina Kazemian
Mohammadhasan Matin
Hedie Soltani
Mahya Beikmohammdi
Amirhossein Mehrpour
Mahmood Bakhtiyari
- Publikationsdatum
- 26.11.2025
- Verlag
- Springer US
- Erschienen in
-
Obesity Surgery / Ausgabe 12/2025
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428 - DOI
- https://doi.org/10.1007/s11695-025-08390-7
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