Skip to main content
main-content

01.12.2012 | Review | Ausgabe 1/2012 Open Access

Cardiovascular Ultrasound 1/2012

Tissue Doppler imaging for diagnosis of coronary artery disease: a systematic review and meta-analysis

Zeitschrift:
Cardiovascular Ultrasound > Ausgabe 1/2012
Autoren:
Rajender Agarwal, Priyanka Gosain, James N Kirkpatrick, Tareq Alyousef, Rami Doukky, Gurpreet Singh, Craig A Umscheid
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1476-7120-10-47) contains supplementary material, which is available to authorized users.

Competing interests

None of the authors had any financial or non-financial competing interests

Authors’ contributions

RA: Conception and design, analysis and interpretation of the data, drafting of the article, final approval of the article. PG: Collection and assembly of data, final approval of the article. JNK: Critical revision of the article for important intellectual content, final approval of the article. TA: Critical revision of the article for important intellectual content, final approval of the article. RD: Critical revision of the article for important intellectual content, final approval of the article. GS: Collection and assembly of data, final approval of the article. CAU: Critical revision of the article for important intellectual content, final approval of the article. All authors read and approved the final manuscript.

Abstract

Global and regional left ventricular (LV) systolic dysfunction is a marker of coronary artery disease (CAD), which is conventionally assessed using two-dimensional echocardiography. Tissue Doppler imaging (TDI) has emerged as an adjunct tool in the diagnosis of regional wall motion abnormalities from CAD. We performed a systematic review and meta-analysis to assess the efficacy of TDI indices in the diagnosis of CAD. We searched MEDLINE and the Cochrane Library for controlled studies comparing TDI measurements in those with and without CAD as confirmed by coronary angiography. Meta-analyses of mean differences in TDI velocities between these populations were performed. Screening of titles and abstracts followed by full-text screening identified 8 studies. At rest, TDI was associated with a significant decrease in the pooled maximum systolic velocity among CAD patients compared to those without CAD [mean difference (MD): -0.66; 95% confidence interval (CI): -0.98 to −0.34]. There were no significant differences in maximum early and late diastolic velocities. Post-stress, TDI was associated with a significant decrease in maximum early diastolic velocity (MD: -1.91; 95% CI: -2.74 to −1.09) and maximum late diastolic velocity (MD: -1.57; 95% CI: -2.95 to −0.18) among CAD patients compared to those without CAD. There was no significant difference in maximum systolic velocity post-stress. Our results suggest that TDI may have a role in the evaluation of CAD. Future studies should evaluate the incremental value of TDI velocities over LV ejection fraction and two dimensional wall motion analysis in the detection of CAD and assessment of its severity. (Word Count: 249)
Zusatzmaterial
Authors’ original file for figure 1
12947_2012_448_MOESM1_ESM.tiff
Authors’ original file for figure 2
12947_2012_448_MOESM2_ESM.tiff
Authors’ original file for figure 3
12947_2012_448_MOESM3_ESM.tiff
Authors’ original file for figure 4
12947_2012_448_MOESM4_ESM.tiff
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2012

Cardiovascular Ultrasound 1/2012 Zur Ausgabe

Neu im Fachgebiet Innere Medizin

Meistgelesene Bücher aus der Inneren Medizin

2017 | Buch

Rheumatologie aus der Praxis

Entzündliche Gelenkerkrankungen – mit Fallbeispielen

Dieses Fachbuch macht mit den wichtigsten chronisch entzündlichen Gelenk- und Wirbelsäulenerkrankungen vertraut. Anhand von über 40 instruktiven Fallbeispielen werden anschaulich diagnostisches Vorgehen, therapeutisches Ansprechen und der Verlauf …

Herausgeber:
Rudolf Puchner

2016 | Buch

Ambulant erworbene Pneumonie

Was, wann, warum – Dieses Buch bietet differenzierte Diagnostik und Therapie der ambulant erworbenen Pneumonie zur sofortigen sicheren Anwendung. Entsprechend der neuesten Studien und Leitlinien aller wichtigen Fachgesellschaften.

Herausgeber:
Santiago Ewig

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Innere Medizin und bleiben Sie gut informiert – ganz bequem per eMail.

© Springer Medizin 

Bildnachweise