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Erschienen in: European Radiology 2/2017

31.05.2016 | Musculoskeletal

Tomosynthesis of the thoracic spine: added value in diagnosing vertebral fractures in the elderly

verfasst von: Mats Geijer, Eirikur Gunnlaugsson, Simon Götestrand, Lars Weber, Håkan Geijer

Erschienen in: European Radiology | Ausgabe 2/2017

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Abstract

Objectives

Thoracic spine radiography becomes more difficult with age. Tomosynthesis is a low-dose tomographic extension of radiography which may facilitate thoracic spine evaluation. This study assessed the added value of tomosynthesis in imaging of the thoracic spine in the elderly.

Methods

Four observers compared the image quality of 50 consecutive thoracic spine radiography and tomosynthesis data sets from 48 patients (median age 67 years, range 55–92 years) on a number of image quality criteria. Observer variation was determined by free-marginal multirater kappa. The conversion factor and effective dose were determined from the dose–area product values.

Results

For all observers significantly more vertebrae were seen with tomosynthesis than with radiography (mean 12.4/9.3, P < 0.001) as well as significantly more fractures (mean 0.9/0.7, P = 0.017). The image quality score for tomosynthesis was significantly higher than for radiography, for all evaluated structures. Tomosynthesis took longer to evaluate than radiography. Despite this, all observers scored a clear preference for tomosynthesis. Observer agreement was substantial (mean κ = 0.73, range 0.51–0.94). The calibration or conversion factor was 0.11 mSv/(Gy cm2) for the combined examination. The resulting effective dose was 0.87 mSv.

Conclusion

Tomosynthesis can increase the detection rate of thoracic vertebral fractures in the elderly, at low added radiation dose.

Key Points

Tomosynthesis helps evaluate the thoracic spine in the elderly.
Observer agreement for thoracic spine tomosynthesis was substantial (mean κ = 0.73).
Significantly more vertebrae and significantly more fractures were seen with tomosynthesis.
Tomosynthesis took longer to evaluate than radiography.
There was a clear preference among all observers for tomosynthesis over radiography.
Literatur
1.
Zurück zum Zitat Gehlbach SH, Bigelow C, Heimisdottir M et al (2000) Recognition of vertebral fracture in a clinical setting. Osteoporos Int 11:577–582CrossRefPubMed Gehlbach SH, Bigelow C, Heimisdottir M et al (2000) Recognition of vertebral fracture in a clinical setting. Osteoporos Int 11:577–582CrossRefPubMed
2.
Zurück zum Zitat Horváth F, Kákossy T (1972) Morphology of Kümmell’s disease in tomograms [Morphologie der Kümmellschen Krankheit auf der Schichtaufnahme]. Z Orthop Ihre Grenzgeb 110:261–265PubMed Horváth F, Kákossy T (1972) Morphology of Kümmell’s disease in tomograms [Morphologie der Kümmellschen Krankheit auf der Schichtaufnahme]. Z Orthop Ihre Grenzgeb 110:261–265PubMed
3.
Zurück zum Zitat Norman A (1970) The value of tomography in the diagnosis of skeletal disorders. Radiol Clin N Am 8:251–258PubMed Norman A (1970) The value of tomography in the diagnosis of skeletal disorders. Radiol Clin N Am 8:251–258PubMed
5.
Zurück zum Zitat Karul M, Bannas P, Schoennagel BP et al (2013) Fractures of the thoracic spine in patients with minor trauma: comparison of diagnostic accuracy and dose of biplane radiography and MDCT. Eur J Radiol 82:1273–1277CrossRefPubMed Karul M, Bannas P, Schoennagel BP et al (2013) Fractures of the thoracic spine in patients with minor trauma: comparison of diagnostic accuracy and dose of biplane radiography and MDCT. Eur J Radiol 82:1273–1277CrossRefPubMed
6.
Zurück zum Zitat Cicala D, Briganti F, Casale L et al (2013) Atraumatic vertebral compression fractures: differential diagnosis between benign osteoporotic and malignant fractures by MRI. Musculoskelet Surg 97:S169–S179CrossRefPubMed Cicala D, Briganti F, Casale L et al (2013) Atraumatic vertebral compression fractures: differential diagnosis between benign osteoporotic and malignant fractures by MRI. Musculoskelet Surg 97:S169–S179CrossRefPubMed
7.
Zurück zum Zitat Dobbins JT 3rd, Godfrey DJ (2003) Digital x-ray tomosynthesis: current state of the art and clinical potential. Phys Med Biol 48:R65–R106CrossRefPubMed Dobbins JT 3rd, Godfrey DJ (2003) Digital x-ray tomosynthesis: current state of the art and clinical potential. Phys Med Biol 48:R65–R106CrossRefPubMed
8.
Zurück zum Zitat Vikgren J, Zachrisson S, Svalkvist A et al (2008) Comparison of chest tomosynthesis and chest radiography for detection of pulmonary nodules: human observer study of clinical cases. Radiology 249:1034–1041CrossRefPubMed Vikgren J, Zachrisson S, Svalkvist A et al (2008) Comparison of chest tomosynthesis and chest radiography for detection of pulmonary nodules: human observer study of clinical cases. Radiology 249:1034–1041CrossRefPubMed
9.
Zurück zum Zitat Vult von Steyern K, Björkman-Burtscher I, Geijer M (2012) Tomosynthesis in pulmonary cystic fibrosis with comparison to radiography and computed tomography: A pictorial review. Insights Imaging 3:81–89CrossRefPubMed Vult von Steyern K, Björkman-Burtscher I, Geijer M (2012) Tomosynthesis in pulmonary cystic fibrosis with comparison to radiography and computed tomography: A pictorial review. Insights Imaging 3:81–89CrossRefPubMed
10.
Zurück zum Zitat Choo JY, Lee KY, Yu A et al (2015) A comparison of digital tomosynthesis and chest radiography in evaluating airway lesions using computed tomography as a reference. Eur Radiol. doi:10.1007/s00330-015-4127-z Choo JY, Lee KY, Yu A et al (2015) A comparison of digital tomosynthesis and chest radiography in evaluating airway lesions using computed tomography as a reference. Eur Radiol. doi:10.​1007/​s00330-015-4127-z
11.
Zurück zum Zitat Park JM, Franken EA Jr, Garg M et al (2007) Breast tomosynthesis: present considerations and future applications. Radiographics 27:S231–S240CrossRefPubMed Park JM, Franken EA Jr, Garg M et al (2007) Breast tomosynthesis: present considerations and future applications. Radiographics 27:S231–S240CrossRefPubMed
12.
Zurück zum Zitat Mermuys K, De Geeter F, Bacher K et al (2010) Digital tomosynthesis in the detection of urolithiasis: diagnostic performance and dosimetry compared with digital radiography with MDCT as the reference standard. AJR Am J Roentgenol 195:161–167CrossRefPubMed Mermuys K, De Geeter F, Bacher K et al (2010) Digital tomosynthesis in the detection of urolithiasis: diagnostic performance and dosimetry compared with digital radiography with MDCT as the reference standard. AJR Am J Roentgenol 195:161–167CrossRefPubMed
13.
Zurück zum Zitat Geijer M, Börjesson AM, Göthlin JH (2011) Clinical utility of tomosynthesis in suspected scaphoid fracture. A pilot study. Skelet Radiol 40:863–867CrossRef Geijer M, Börjesson AM, Göthlin JH (2011) Clinical utility of tomosynthesis in suspected scaphoid fracture. A pilot study. Skelet Radiol 40:863–867CrossRef
14.
Zurück zum Zitat Ottenin MA, Jacquot A, Grospretre O et al (2012) Evaluation of the diagnostic performance of tomosynthesis in fractures of the wrist. AJR Am J Roentgenol 198:180–186CrossRefPubMed Ottenin MA, Jacquot A, Grospretre O et al (2012) Evaluation of the diagnostic performance of tomosynthesis in fractures of the wrist. AJR Am J Roentgenol 198:180–186CrossRefPubMed
15.
Zurück zum Zitat Ha AS, Lee AY, Hippe DS et al (2015) Digital tomosynthesis to evaluate fracture healing: prospective comparison with radiography and CT. AJR Am J Roentgenol 205:136–141CrossRefPubMed Ha AS, Lee AY, Hippe DS et al (2015) Digital tomosynthesis to evaluate fracture healing: prospective comparison with radiography and CT. AJR Am J Roentgenol 205:136–141CrossRefPubMed
16.
Zurück zum Zitat Canella C, Philippe P, Pansini V et al (2011) Use of tomosynthesis for erosion evaluation in rheumatoid arthritic hands and wrists. Radiology 258:199–205CrossRefPubMed Canella C, Philippe P, Pansini V et al (2011) Use of tomosynthesis for erosion evaluation in rheumatoid arthritic hands and wrists. Radiology 258:199–205CrossRefPubMed
17.
Zurück zum Zitat Aoki T, Fujii M, Yamashita Y et al (2014) Tomosynthesis of the wrist and hand in patients with rheumatoid arthritis: comparison with radiography and MRI. AJR Am J Roentgenol 202:386–390CrossRefPubMed Aoki T, Fujii M, Yamashita Y et al (2014) Tomosynthesis of the wrist and hand in patients with rheumatoid arthritis: comparison with radiography and MRI. AJR Am J Roentgenol 202:386–390CrossRefPubMed
18.
Zurück zum Zitat Svalkvist A, Söderman C, Båth M (2015) Effective dose to patients from thoracic spine examinations with tomosynthesis. Radiat Prot Dosim. doi:10.1093/rpd/ncv498 Svalkvist A, Söderman C, Båth M (2015) Effective dose to patients from thoracic spine examinations with tomosynthesis. Radiat Prot Dosim. doi:10.​1093/​rpd/​ncv498
19.
Zurück zum Zitat Sabol JM (2009) A Monte Carlo estimation of effective dose in chest tomosynthesis. Med Phys 36:5480–5487CrossRefPubMed Sabol JM (2009) A Monte Carlo estimation of effective dose in chest tomosynthesis. Med Phys 36:5480–5487CrossRefPubMed
20.
Zurück zum Zitat Genant HK, Wu CY, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8:1137–1148CrossRefPubMed Genant HK, Wu CY, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8:1137–1148CrossRefPubMed
22.
Zurück zum Zitat Tapiovaara M, Siiskonen T (2008) PCXMC—a Monte Carlo program for calculating patient doses in medical X-ray examinations, 2nd edn. STUK-A231. STUK, Helsinki Tapiovaara M, Siiskonen T (2008) PCXMC—a Monte Carlo program for calculating patient doses in medical X-ray examinations, 2nd edn. STUK-A231. STUK, Helsinki
23.
Zurück zum Zitat IRCP (2007) The 2007 recommendations of the International Commission on Radiological Protection. ICRP Publication 103. Pergamon Press, Oxford IRCP (2007) The 2007 recommendations of the International Commission on Radiological Protection. ICRP Publication 103. Pergamon Press, Oxford
24.
Zurück zum Zitat Båth M, Söderman C, Svalkvist A (2014) A simple method to retrospectively estimate patient dose-area product for chest tomosynthesis examinations performed using VolumeRAD. Med Phys 41:101905CrossRefPubMed Båth M, Söderman C, Svalkvist A (2014) A simple method to retrospectively estimate patient dose-area product for chest tomosynthesis examinations performed using VolumeRAD. Med Phys 41:101905CrossRefPubMed
25.
Zurück zum Zitat Båth M, Söderman C, Svalkvist A (2015) Retrospective estimation of patient dose-area product in thoracic spine tomosynthesis performed using VolumeRAD. Radiat Prot Dosim. doi:10.1093/rpd/ncv475 Båth M, Söderman C, Svalkvist A (2015) Retrospective estimation of patient dose-area product in thoracic spine tomosynthesis performed using VolumeRAD. Radiat Prot Dosim. doi:10.​1093/​rpd/​ncv475
27.
Zurück zum Zitat Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRefPubMed Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRefPubMed
28.
Zurück zum Zitat Ceder E, Danielson B, Kovàč P et al (2016) Thoracic spine imaging: a comparison between radiography and tomosynthesis using visual grading characteristics. Radiat Prot Dosim. doi:10.1093/rpd/ncv559 Ceder E, Danielson B, Kovàč P et al (2016) Thoracic spine imaging: a comparison between radiography and tomosynthesis using visual grading characteristics. Radiat Prot Dosim. doi:10.​1093/​rpd/​ncv559
29.
Zurück zum Zitat Mettler FA, Huda W, Yoshizumi TT, Mahesh M (2008) Effective doses in radiology and diagnostic nuclear medicine: a catalog. Radiology 248:254–263CrossRefPubMed Mettler FA, Huda W, Yoshizumi TT, Mahesh M (2008) Effective doses in radiology and diagnostic nuclear medicine: a catalog. Radiology 248:254–263CrossRefPubMed
30.
Zurück zum Zitat Leitz W, Almén A (2008) Doses to patients from x-ray examinations in Sweden – 1999 and 2006, SSI Report 2008:2 [Patientstråldoser vid röntgendiagnostik i Sverige – 1999 och 2006]. Swedish Radiation Safety Authority, Stockholm Leitz W, Almén A (2008) Doses to patients from x-ray examinations in Sweden – 1999 and 2006, SSI Report 2008:2 [Patientstråldoser vid röntgendiagnostik i Sverige – 1999 och 2006]. Swedish Radiation Safety Authority, Stockholm
31.
Zurück zum Zitat Obuchowski NA (2004) How many observers are needed in clinical studies of medical imaging? AJR Am J Roentgenol 182:867–869CrossRefPubMed Obuchowski NA (2004) How many observers are needed in clinical studies of medical imaging? AJR Am J Roentgenol 182:867–869CrossRefPubMed
32.
Zurück zum Zitat Sadatsafavi M, Najafzadeh M, Lynd L, Marra C (2008) Reliability studies of diagnostic tests are not using enough observers for robust estimation of interobserver agreement: a simulation study. J Clin Epidemiol 61:722–727CrossRefPubMed Sadatsafavi M, Najafzadeh M, Lynd L, Marra C (2008) Reliability studies of diagnostic tests are not using enough observers for robust estimation of interobserver agreement: a simulation study. J Clin Epidemiol 61:722–727CrossRefPubMed
Metadaten
Titel
Tomosynthesis of the thoracic spine: added value in diagnosing vertebral fractures in the elderly
verfasst von
Mats Geijer
Eirikur Gunnlaugsson
Simon Götestrand
Lars Weber
Håkan Geijer
Publikationsdatum
31.05.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 2/2017
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4392-5

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