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2493 Suchergebnisse für:

Tourette-Syndrom 

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  1. Open Access 13.04.2024 | Online First

    Agreement between self-, mother and father proxy-reports on health-related quality of life in adolescents with Tourette syndrome

    This study aimed to investigate agreement and discrepancies between parent proxy- and adolescent self-reports on assessments of adolescents’ health-related quality of life (HRQoL), and the role that individual factors may play in parent-adolescent …

  2. 18.04.2024 | Online First

    Abnormal H3K4 enzyme catalytic activity and neuronal morphology caused by ASH1L mutations in individuals with Tourette syndrome

    ASH1L potentially contributes to Tourette syndrome (TS) and other neuropsychiatric disorders, as our previous studies have shown. It regulates essential developmental genes by counteracting polycomb-mediated transcriptional repression, which …

  3. 14.11.2023 | ReviewPaper

    Pharmacological treatment of Tourette’s syndrome: from the past to the future

    Tourette’s syndrome (TS) is a neuropsychiatric disease featuring tics and vocal tics, with a prevalence of approximately 1%, including 75% of the total number of male patients. TS seriously disturbs the patients’ career, education, and life and …

  4. Open Access 30.12.2023 | Online First

    Reframing stigma in Tourette syndrome: an updated scoping review

    Persistent tic disorders (PTD) such as Tourette’s syndrome (TS) are common childhood-onset neurodevelopmental disorders. Stigmatization of individuals with these disorders remains an ongoing problem. The purpose of this scoping review is to serve …

  5. 21.12.2023 | Online First

    Psychosocial experiences in youth with Tourette syndrome: a systematic review and meta-synthesis

    Suffering from Tourette syndrome (TS) disrupts the daily lives and interpersonal relationships of patients. The psychosocial experiences of young people with TS are not yet clear. The aim of the systematic review is to identify and synthesize the …

  6. Open Access 20.05.2023 | OriginalPaper

    What distinguishes patients with mass social media-induced illness presenting with Tourette-like behavior from those with Tourette syndrome? Results of a prospective cohort study

    Since 2019, a global increase in patients presenting with functional Tourette-like behaviors (FTB) has been observed. This has been related to the exposure of tic-related content in social media, although other factors seem to further fuel this …

  7. Open Access 01.12.2023 | ReviewPaper

    Prevalence of depression and anxiety in patients with Tourette syndrome; 1997 to 2022: a systematic review and meta-analysis

    Tourette Syndrome (TS) is a disorder in which the patient has a history of multiple motor and vocal tics. Depression and anxiety are common in these patients. The results of the studies show different prevalence of these disorders in patients with …

  8. Open Access 01.12.2023 | OriginalPaper

    Alterations in the topological organization of the default-mode network in Tourette syndrome

    Tourette's syndrome (TS) is a childhood-onset neurodevelopmental movement disorder characterized by multiple motor and vocal tics lasting more than a year prior to the age of 18 years old [ 1 ]. TS, once considered a rare condition, is now …

  9. Open Access 01.12.2023 | OriginalPaper

    Tourette-like syndrome secondary to Kleefstra syndrome 1 with a de novo microdeletion in the EHMT1 gene

    Tourette syndrome is a chronic neurodevelopmental disorder with involuntary motor and vocal tics like eye blinking, facial grimacing, throat clearing, sniffing, or unintentional vocalizations [ 1 ]. It typically manifests in childhood and may …

  10. Open Access 01.12.2023 | OriginalPaper

    The microstructural change of the brain and its clinical severity association in pediatric Tourette syndrome patients

    Tic disorders, characterized by rapid and stereotyped movements or sounds, are prevalent pediatric neurological conditions. Gilles de la Tourette syndrome (GTS) is a particular form of tic disorder that typically emerges during childhood …

  11. Open Access 02.12.2022 | OriginalPaper

    How does Tourette syndrome impact adolescents’ daily living? A text mining study

    Tourette syndrome (TS) is a neurodevelopmental disease characterized by the presence of multiple chronic motor and vocal tics. In addition, TS is frequently associated with attention-deficit hyperactivity disorder (ADHD) and obsessive–compulsive …

  12. 11.06.2023 | OriginalPaper

    Real-world experience with VMAT2 inhibitors in Tourette syndrome

    Vesicular monoamine transporters (VMAT) are proteins responsible for presynaptic packaging of monoaminergic neurotransmitters including dopamine, norepinephrine, epinephrine, serotonin and histamine ( 1 , 2 ). Many hyperkinetic movement disorders …

  13. 28.04.2023 | OriginalPaper

    Contrasting features between Tourette syndrome and secondary tic disorders

    Tics are rapid, recurrent, non-rhythmic movements or emitted sounds. Tics are the hallmark of Tourette syndrome (TS); however, a number of other disorders may be associated with tics, so-called secondary tic disorders (STD). We assessed clinical …

  14. Open Access 01.12.2022 | OriginalPaper

    The Cerebellum in Drug-naive Children with Tourette Syndrome and Obsessive–Compulsive Disorder

    Tourette syndrome (TS) and obsessive–compulsive disorder (OCD) are two neurodevelopmental disorders characterized by repetitive behaviors. Our recent study in drug-naive children with TS and OCD provided evidence of cerebellar involvement in both …

  15. 01.02.2023 | OriginalPaper

    Oromandibular tics associated with Tourette syndrome

    Tics are among the most common movement disorders (MDs). They are characterized by abrupt, rapid, movements or sounds that are repetitive but may fluctuate in frequency, intensity and complexity. Tourette syndrome (TS), a childhood-onset disorder …

  16. Open Access 01.04.2022 | OriginalPaper

    Exculpation and Stigma in Tourette Syndrome

    An Experimental Philosophy Study

    Biological accounts of psychopathology have been positively received. Attribution theory, a leading theory in social psychology [ 1 ], predicts that the less responsibility one attributes to an agent, the less they will be blamed and with this, the …

  17. Open Access 17.02.2023 | BriefCommunication

    Advances in Tourette’s syndrome

    Tourette’s is a neurodevelopmental disorder usually beginning in childhood or adolescence and presents with involuntary tics or vocalisations and is more common in males. It has an overall childhood prevalence of around 0.6% and has no ethnic or …

  18. Open Access 01.02.2022 | ReviewPaper

    Non-invasive brain stimulation as therapy: systematic review and recommendations with a focus on the treatment of Tourette syndrome

    Tourette syndrome (TS) is a neurodevelopmental condition characterised by tics, which are stereotyped movements and/or vocalisations. Tics often cause difficulties in daily life and many with TS express a desire to reduce and/or gain control over …

  19. 24.06.2021 | Bewegungsstörungen | ContinuingEducation

    Tourette-Syndrom: Wer tickt hier richtig?

    Herausfordernde Differenzialdiagnostik

    Bei typischer Symptomkonstellation ist die Diagnose Tourette-Syndrom einfach zu stellen. In jüngster Zeit stellen sich jedoch zunehmend Betroffene vor, die funktionelle Störungen mit "Tic- und Tourette-ähnlichen" Bewegungen und Lautäußerungen haben. Diese Differenzierung stellt eine diagnostische Herausforderung dar, ist aber unabdingbare Voraussetzung für eine adäquate Therapie.

  20. 08.04.2021 | Ticstörungen | ContinuingEducation
    Herausfordernde Differenzialdiagnostik

    Tourette-Syndrom: Wer tickt hier richtig?

    Bei typischer Symptomkonstellation ist die Tourette-Syndrom-Diagnose einfach zu stellen. In jüngster Zeit stellen sich in spezialisierten Zentren jedoch zunehmend Betroffene vor, die "Tic- und Tourette-ähnliche" funktionelle Störungen haben. Diese Differenzierung stellt eine diagnostische Herausforderung dar.

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