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Erschienen in: Medicine, Health Care and Philosophy 1/2019

07.06.2018 | Short Communication

Toward an accelerated adoption of data-driven findings in medicine

Research, skepticism, and the need to speed up public visibility of data-driven findings

verfasst von: Uri Kartoun

Erschienen in: Medicine, Health Care and Philosophy | Ausgabe 1/2019

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Abstract

To accelerate the adoption of a new method with a high potential to replace or extend an existing, presumably less accurate, medical scoring system, evaluation should begin days after the new concept is presented publicly, not years or even decades later. Metaphorically speaking, as chameleons capable of quickly changing colors to help their bodies adjust to changes in temperature or light, health-care decision makers should be capable of more quickly evaluating new data-driven insights and tools and should integrate the highest performing ones into national and international care systems. Doing so is essential, because it will truly save the lives of many individuals.
Literatur
Zurück zum Zitat Ananthakrishnan, A. N., T. Cai, G. Savova, S. C. Cheng, P. Chen, R. G. Perez, V. S. Gainer, S. N. Murphy, P. Szolovits, Z. Xia, S. Shaw, S. Churchill, E. W. Karlson, I. Kohane, R. M. Plenge, and K. P. Liao. 2013. Improving case definition of Crohn’s disease and ulcerative colitis in electronic medical records using natural language processing: A novel informatics approach. Inflammatory Bowel Diseases 19 (7): 1411–1420.CrossRef Ananthakrishnan, A. N., T. Cai, G. Savova, S. C. Cheng, P. Chen, R. G. Perez, V. S. Gainer, S. N. Murphy, P. Szolovits, Z. Xia, S. Shaw, S. Churchill, E. W. Karlson, I. Kohane, R. M. Plenge, and K. P. Liao. 2013. Improving case definition of Crohn’s disease and ulcerative colitis in electronic medical records using natural language processing: A novel informatics approach. Inflammatory Bowel Diseases 19 (7): 1411–1420.CrossRef
Zurück zum Zitat Beam, A. L., U. Kartoun, J. K. Pai, A. K. Chatterjee, T. P. Fitzgerald, S. Y. Shaw, and I. S. Kohane. 2017. Predictive modeling of physician-patient dynamics that influence sleep medication prescriptions and clinical decision-making. Scientific Reports 7: 42282.CrossRef Beam, A. L., U. Kartoun, J. K. Pai, A. K. Chatterjee, T. P. Fitzgerald, S. Y. Shaw, and I. S. Kohane. 2017. Predictive modeling of physician-patient dynamics that influence sleep medication prescriptions and clinical decision-making. Scientific Reports 7: 42282.CrossRef
Zurück zum Zitat Bushak, L. 2015. Mad Scientist: 6 scientists who were dismissed as crazy, only to be proven right years later. Medical Daily, Nov 18, 2015. Bushak, L. 2015. Mad Scientist: 6 scientists who were dismissed as crazy, only to be proven right years later. Medical Daily, Nov 18, 2015.
Zurück zum Zitat Byrne, C. D., and G. Targher. 2015. NAFLD: A multisystem disease. Journal of Hepatology 62: S47–S64.CrossRef Byrne, C. D., and G. Targher. 2015. NAFLD: A multisystem disease. Journal of Hepatology 62: S47–S64.CrossRef
Zurück zum Zitat Charlton, M. 2008. Cirrhosis and liver failure in nonalcoholic fatty liver disease: Molehill or mountain? Hepatology 47: 1431–1433.CrossRef Charlton, M. 2008. Cirrhosis and liver failure in nonalcoholic fatty liver disease: Molehill or mountain? Hepatology 47: 1431–1433.CrossRef
Zurück zum Zitat Corey, K. E., U. Kartoun, H. Zheng, R. T. Chung, and S. Y. Shaw. 2016. Using an electronic medical records database to identify nontraditional cardiovascular risk factors in nonalcoholic fatty liver disease. The American Journal of Gastroenterology 111 (5): 671–676.CrossRef Corey, K. E., U. Kartoun, H. Zheng, R. T. Chung, and S. Y. Shaw. 2016. Using an electronic medical records database to identify nontraditional cardiovascular risk factors in nonalcoholic fatty liver disease. The American Journal of Gastroenterology 111 (5): 671–676.CrossRef
Zurück zum Zitat ElMaghawry, M., A. Zanatta, and F. Zampieri. 2014. The discovery of pulmonary circulation: From Imhotep to William Harvey. Global Cardiology Science and Practice 2014(2):103–116. ElMaghawry, M., A. Zanatta, and F. Zampieri. 2014. The discovery of pulmonary circulation: From Imhotep to William Harvey. Global Cardiology Science and Practice 2014(2):103–116.
Zurück zum Zitat Freeman, R. B. Jr, R. H. Wiesner, A. Harper, S. V. McDiarmid, J. Lake, E. Edwards, R. Merion, R. Wolfe, J. Turcotte, and L. Teperman. 2002. UNOS/OPTN Liver Disease Severity Score, UNOS/OPTN Liver and Intestine, and UNOS/OPTN Pediatric Transplantation Committees. The new liver allocation system: Moving toward evidence-based transplantation policy. Liver Transplantation 8 (9): 851–858.CrossRef Freeman, R. B. Jr, R. H. Wiesner, A. Harper, S. V. McDiarmid, J. Lake, E. Edwards, R. Merion, R. Wolfe, J. Turcotte, and L. Teperman. 2002. UNOS/OPTN Liver Disease Severity Score, UNOS/OPTN Liver and Intestine, and UNOS/OPTN Pediatric Transplantation Committees. The new liver allocation system: Moving toward evidence-based transplantation policy. Liver Transplantation 8 (9): 851–858.CrossRef
Zurück zum Zitat Institute of Medicine. 1999. Analysis of waiting times. In Organ procurement and transplantation: Assessing current policies and the potential impact of the DHHS final rule, ed. Committee on Organ Procurement, and Transplantation Policy, 57–58. Washington, D.C.: National Academy Press. Institute of Medicine. 1999. Analysis of waiting times. In Organ procurement and transplantation: Assessing current policies and the potential impact of the DHHS final rule, ed. Committee on Organ Procurement, and Transplantation Policy, 57–58. Washington, D.C.: National Academy Press.
Zurück zum Zitat Kamath, P. S., and W. R. Kim. 2007. The model for end-stage liver disease (MELD). Hepatology 45 (3): 797–805.CrossRef Kamath, P. S., and W. R. Kim. 2007. The model for end-stage liver disease (MELD). Hepatology 45 (3): 797–805.CrossRef
Zurück zum Zitat Kartoun, U. 2017a. Text nailing: An efficient human-in-the-loop text-processing method 2017. ACM Interactions 24 (6): 44–49.CrossRef Kartoun, U. 2017a. Text nailing: An efficient human-in-the-loop text-processing method 2017. ACM Interactions 24 (6): 44–49.CrossRef
Zurück zum Zitat Kartoun, U. 2017b. Beyond brute force. Communications of the ACM 60 (10): 8–9.CrossRef Kartoun, U. 2017b. Beyond brute force. Communications of the ACM 60 (10): 8–9.CrossRef
Zurück zum Zitat Kartoun, U. 2018. Toward an equation that anticipates AI risks. Communications of the ACM 61 (2): 8–9.CrossRef Kartoun, U. 2018. Toward an equation that anticipates AI risks. Communications of the ACM 61 (2): 8–9.CrossRef
Zurück zum Zitat Kartoun, U., V. Kumar, A. Brettman, S. Yu, K. Liao, E. Karlson, A. Ananthakrishnan, Z. Xia, V. Gainer, A. Cagan, S. Murphy, S. Churchill, I. Kohane, P. Szolovits, T. Cai, and S. Y. Shaw. 2015. A risk model for 30-day heart failure re-admission using electronic medical records. 2015 Joint Summits on Translational Science, San Francisco, CA. Kartoun, U., V. Kumar, A. Brettman, S. Yu, K. Liao, E. Karlson, A. Ananthakrishnan, Z. Xia, V. Gainer, A. Cagan, S. Murphy, S. Churchill, I. Kohane, P. Szolovits, T. Cai, and S. Y. Shaw. 2015. A risk model for 30-day heart failure re-admission using electronic medical records. 2015 Joint Summits on Translational Science, San Francisco, CA.
Zurück zum Zitat Kartoun, U., K. Corey, H. Zheng, and S. Shaw. 2016. A prediction model to assess mortality risk in cirrhosis. 2016 Joint Summits on Translational Science, San Francisco, CA. Kartoun, U., K. Corey, H. Zheng, and S. Shaw. 2016. A prediction model to assess mortality risk in cirrhosis. 2016 Joint Summits on Translational Science, San Francisco, CA.
Zurück zum Zitat Kartoun, U., R. Aggarwal, A. Beam, J. Pai, A. Chatterjee, T. Fitzgerald, I. Kohane, and S. Shaw. 2018. Development of an algorithm to identify patients with physician-documented insomnia. Scientific Reports 8: 7862.CrossRef Kartoun, U., R. Aggarwal, A. Beam, J. Pai, A. Chatterjee, T. Fitzgerald, I. Kohane, and S. Shaw. 2018. Development of an algorithm to identify patients with physician-documented insomnia. Scientific Reports 8: 7862.CrossRef
Zurück zum Zitat Kim, W. R., S. W. Biggins, W. K. Kremers, R. H. Wiesner, P. S. Kamath, J. T. Benson, E. Edwards, and T. M. Therneau. 2008. Hyponatremia and mortality among patients on the liver-transplant waiting list. New England Journal of Medicine 359 (10): 1018–1026.CrossRef Kim, W. R., S. W. Biggins, W. K. Kremers, R. H. Wiesner, P. S. Kamath, J. T. Benson, E. Edwards, and T. M. Therneau. 2008. Hyponatremia and mortality among patients on the liver-transplant waiting list. New England Journal of Medicine 359 (10): 1018–1026.CrossRef
Zurück zum Zitat Liao, K. P., T. Cai, V. Gainer, S. Goryachev, Q. Zeng-treitler, S. Raychaudhuri, P. Szolovits, S. Churchill, S. Murphy, I. Kohane, E. W. Karlson, and R. M. Plenge. 2010. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care & Research 62 (8): 1120–1127.CrossRef Liao, K. P., T. Cai, V. Gainer, S. Goryachev, Q. Zeng-treitler, S. Raychaudhuri, P. Szolovits, S. Churchill, S. Murphy, I. Kohane, E. W. Karlson, and R. M. Plenge. 2010. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care & Research 62 (8): 1120–1127.CrossRef
Zurück zum Zitat Londoño, M. C., A. Cárdenas, M. Guevara, L. Quintó, D. de Las Heras, M. Navasa, A. Rimola, J. C. Garcia-Valdecasas, V. Arroyo, and P. Ginès. 2007. MELD score and serum sodium in the prediction of survival of patients with cirrhosis awaiting liver transplantation. Gut 56 (9): 1283–1290.CrossRef Londoño, M. C., A. Cárdenas, M. Guevara, L. Quintó, D. de Las Heras, M. Navasa, A. Rimola, J. C. Garcia-Valdecasas, V. Arroyo, and P. Ginès. 2007. MELD score and serum sodium in the prediction of survival of patients with cirrhosis awaiting liver transplantation. Gut 56 (9): 1283–1290.CrossRef
Zurück zum Zitat Luca, A., B. Angermayr, G. Bertolini, F. Koenig, G. Vizzini, M. Ploner, M. Peck-Radosavljevic, B. Gridelli, and J. Bosch. 2007. An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis. Liver Transplantation 13 (8): 1174–1180.CrossRef Luca, A., B. Angermayr, G. Bertolini, F. Koenig, G. Vizzini, M. Ploner, M. Peck-Radosavljevic, B. Gridelli, and J. Bosch. 2007. An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis. Liver Transplantation 13 (8): 1174–1180.CrossRef
Zurück zum Zitat Malinchoc, M., P. S. Kamath, F. D. Gordon, C. J. Peine, J. Rank, and P. C. ter Borg. 2000. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology 31 (4): 864–871.CrossRef Malinchoc, M., P. S. Kamath, F. D. Gordon, C. J. Peine, J. Rank, and P. C. ter Borg. 2000. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology 31 (4): 864–871.CrossRef
Zurück zum Zitat Mehta, N., T. Singh, R. Lopez, and N. Alkhouri. 2016. The heart age is increased in patients with nonalcoholic fatty liver disease and correlates with fibrosis and hepatocyte ballooning. The American Journal of Gastroenterology 111 (12): 1853–1854.CrossRef Mehta, N., T. Singh, R. Lopez, and N. Alkhouri. 2016. The heart age is increased in patients with nonalcoholic fatty liver disease and correlates with fibrosis and hepatocyte ballooning. The American Journal of Gastroenterology 111 (12): 1853–1854.CrossRef
Zurück zum Zitat Mulligan, D. C., and R. Hirose. 2014. OPTN/UNOS, Liver and Intestinal Organ Transplantation Committee. Report to the Board of Directors. June 23–24, 2014, Richmond, Virginia. Mulligan, D. C., and R. Hirose. 2014. OPTN/UNOS, Liver and Intestinal Organ Transplantation Committee. Report to the Board of Directors. June 23–24, 2014, Richmond, Virginia.
Zurück zum Zitat Musso, G., R. Gambino, M. Cassader, and G. Pagano. 2011. Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of noninvasive tests for liver disease severity. Annals of Medicine 43: 617–649.CrossRef Musso, G., R. Gambino, M. Cassader, and G. Pagano. 2011. Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of noninvasive tests for liver disease severity. Annals of Medicine 43: 617–649.CrossRef
Zurück zum Zitat Ruf, A. E., W. K. Kremers, L. L. Chavez, V. I. Descalzi, L. G. Podesta, and F. G. Villamil. 2005. Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone. Liver Transplantation 11 (3): 336–343.CrossRef Ruf, A. E., W. K. Kremers, L. L. Chavez, V. I. Descalzi, L. G. Podesta, and F. G. Villamil. 2005. Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone. Liver Transplantation 11 (3): 336–343.CrossRef
Zurück zum Zitat Simon, T. G., U. Kartoun, H. Zheng, A. T. Chan, R. T. Chung, S. Shaw, and K. E. Corey. 2017. MELD-Na score predicts incident major cardiovascular events, in patients with nonalcoholic fatty liver disease. Hepatology Communications 1 (5): 429–438.CrossRef Simon, T. G., U. Kartoun, H. Zheng, A. T. Chan, R. T. Chung, S. Shaw, and K. E. Corey. 2017. MELD-Na score predicts incident major cardiovascular events, in patients with nonalcoholic fatty liver disease. Hepatology Communications 1 (5): 429–438.CrossRef
Zurück zum Zitat Tudoroiu, M. I., G. Constantin, L. Pâslaru, S. Iacob, C. Gheorghe, I. Popescu, D. Tomescu, and L. S. Gheorghe. 2018. The combination of serum cystatin C, urinary kidney injury molecule-1 and MELD-Plus score predicts early acute kidney injury after liver transplantation. Surgery, Gastroenterology and Oncology 23 (2): 121–126.CrossRef Tudoroiu, M. I., G. Constantin, L. Pâslaru, S. Iacob, C. Gheorghe, I. Popescu, D. Tomescu, and L. S. Gheorghe. 2018. The combination of serum cystatin C, urinary kidney injury molecule-1 and MELD-Plus score predicts early acute kidney injury after liver transplantation. Surgery, Gastroenterology and Oncology 23 (2): 121–126.CrossRef
Zurück zum Zitat Uzuner, O., Y. Luo, and P. Szolovits. 2007. Evaluating the state-of-the-art in automatic de-identification. Journal of the American Medical Informatics Association 14 (5): 550–563.CrossRef Uzuner, O., Y. Luo, and P. Szolovits. 2007. Evaluating the state-of-the-art in automatic de-identification. Journal of the American Medical Informatics Association 14 (5): 550–563.CrossRef
Zurück zum Zitat Uzuner, O., I. Goldstein, Y. Luo, and I. Kohane. 2008. Identifying patient smoking status from medical discharge records. Journal of the American Medical Informatics Association 15 (1): 14–24.CrossRef Uzuner, O., I. Goldstein, Y. Luo, and I. Kohane. 2008. Identifying patient smoking status from medical discharge records. Journal of the American Medical Informatics Association 15 (1): 14–24.CrossRef
Metadaten
Titel
Toward an accelerated adoption of data-driven findings in medicine
Research, skepticism, and the need to speed up public visibility of data-driven findings
verfasst von
Uri Kartoun
Publikationsdatum
07.06.2018
Verlag
Springer Netherlands
Erschienen in
Medicine, Health Care and Philosophy / Ausgabe 1/2019
Print ISSN: 1386-7423
Elektronische ISSN: 1572-8633
DOI
https://doi.org/10.1007/s11019-018-9845-y

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