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01.12.2012 | Primary research | Ausgabe 1/2012 Open Access

Cancer Cell International 1/2012

Toxicities effects of pharmaceutical, olive mill and textile wastewaters before and after degradation by Pseudomonas putida mt-2

Cancer Cell International > Ausgabe 1/2012
Hedi Ben Mansour, Afef Dellai, Yosra Ayed
Wichtige Hinweise
Hedi Ben Mansour, Afef Dellai contributed equally to this work.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

HBM: Was responsible for the conception and design, testing and data acquisition, analysis and data interpretation and drafted the manuscript. AD: made contribution to the study algogenic activities. YA: made contribution to convulsing activity. All authors read and approved the final manuscript.



Removal of numerous classes of chemical pollutants from the industrial wastewater such as textile, pharmaceutical and olive mill using conventional wastewater treatment, is incomplete and several studies suggested that improvement of this situation would require the application of biological treatment techniques. Dyes, polyphenols and drugs are an environmental pollutants extremely toxics to plants and other living organisms including humans. These effluents were previously treated by Pseudomonas putida. The main of this work was to evaluate the in vivo toxicity of the three wastewaters.


Writhes and convulsant effect of effluents were carried out and were compared to the treated effluents. Only pharmaceutical wastewater was exhibited a convulsant effect which observed in mice treated by effluent. On the other hand, all industrial wastewater induced significantly an algogenic effects particularly when mice were treated by the pharmaceutical wastewater (Number of writhes = 44).


Toxicity was totally removed when mice were treated by the bio remediated effluent. This indicates that P. putida was able to completely detoxify the toxic industrial effluent.
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