Skip to main content
Erschienen in: International Urogynecology Journal 5/2017

14.11.2016 | Original Article

Trans-abdominal ultrasound shear wave elastographyfor quantitative assessment of female bladder neck elasticity

verfasst von: David Sheyn, Yasmine Ahmed, Nami Azar, Sherif El-Nashar, Adonis Hijaz, Sangeeta Mahajan

Erschienen in: International Urogynecology Journal | Ausgabe 5/2017

Einloggen, um Zugang zu erhalten

Abstract

Introduction and hypothesis

Disorders of micturition result from a wide variety of conditions and evaluation often involves multiple diagnostic modalities. However, the sensitivity and specificity of these techniques are highly variable and may not always yield a diagnosis. Novel imaging techniques such as ultrasound shear wave elastography may help to improve diagnostic accuracy.

Methods

Continent women were recruited from outpatient gynecology offices from a tertiary medical system. Participants underwent ultrasound evaluation with measurement of the shear wave velocity (SWV) of the bladder neck (BN). SWV was used to determine the Young’s modulus of the bladder neck. The median bladder neck stiffness was calculated and univariate and step-wise and backward multivariate logistic regression analyses were used to identify significant patient characteristics associated with bladder neck stiffness above or below the median.

Results

Fifty-seven women underwent SWE of the bladder; 12 were excluded, and 45 were included in the analysis. The median bladder neck stiffness of the study population was 22 (17.1–28.2) kPa. Age greater than 45 years was associated with a bladder neck stiffness above the median, OR 8.39, p < 0.001. Having no vaginal deliveries was also associated with a bladder neck stiffness greater than 22 kPa, unadjusted OR 4.76 (95 % CI 1.41–20.0, p = 0.012). Bladder volume and bladder neck thickness were not significantly associated with bladder neck stiffness above or below the median.

Conclusion

Trans-abdominal shear wave elastography can be used to quantitatively assess bladder neck stiffness. This technique may potentially be useful for evaluating chronic urinary retention.
Literatur
1.
Zurück zum Zitat Rees DL, Whitfield HN, Islam AK, Doyle PT, Mayo ME, Wickham JE. Urodynamic findings in adult females with frequency and dysuria. Br J Urol. 1975;47(7):853–60.CrossRefPubMed Rees DL, Whitfield HN, Islam AK, Doyle PT, Mayo ME, Wickham JE. Urodynamic findings in adult females with frequency and dysuria. Br J Urol. 1975;47(7):853–60.CrossRefPubMed
2.
Zurück zum Zitat Griffiths DJ. The mechanics of the urethra and of micturition. Br J Urol. 1973;45(5):497–507.CrossRefPubMed Griffiths DJ. The mechanics of the urethra and of micturition. Br J Urol. 1973;45(5):497–507.CrossRefPubMed
3.
Zurück zum Zitat Traube LE, Chaudhari V, Patel MK, Raman SS. Cross-sectional imaging of the female urethra. In: Cross-sectional imaging of the abdomen and pelvis. New York: Springer; 2015. p. 993–1021. Traube LE, Chaudhari V, Patel MK, Raman SS. Cross-sectional imaging of the female urethra. In: Cross-sectional imaging of the abdomen and pelvis. New York: Springer; 2015. p. 993–1021.
4.
Zurück zum Zitat Chapple C, Sievert KD, MacDiarmid S, Khullar V, Radziszewski P, Nardo C, et al. OnabotulinumtoxinA 100 U significantly improves all idiopathic overactive bladder symptoms and quality of life in patients with overactive bladder and urinary incontinence: a randomised, double-blind, placebo-controlled trial. Eur Urol. 2013;64(2):249–56.CrossRefPubMed Chapple C, Sievert KD, MacDiarmid S, Khullar V, Radziszewski P, Nardo C, et al. OnabotulinumtoxinA 100 U significantly improves all idiopathic overactive bladder symptoms and quality of life in patients with overactive bladder and urinary incontinence: a randomised, double-blind, placebo-controlled trial. Eur Urol. 2013;64(2):249–56.CrossRefPubMed
5.
Zurück zum Zitat Avery JC, Stocks N. Urinary incontinence, depression and psychosocial factors—a review of population studies. EMJ. 2016;1(1):58–67 Avery JC, Stocks N. Urinary incontinence, depression and psychosocial factors—a review of population studies. EMJ. 2016;1(1):58–67
6.
Zurück zum Zitat Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. IV. Bladder outlet obstruction. J Urol. 1993;150(5 Pt 2):1681–95.PubMed Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. IV. Bladder outlet obstruction. J Urol. 1993;150(5 Pt 2):1681–95.PubMed
7.
Zurück zum Zitat Falconer C, Blomgren B, Johansson O, Ulmsten U, Malmström A, Westergren-Thorsson G, et al. Different organization of collagen fibrils in stress-incontinent women of fertile age. Acta Obstet Gynecol Scand. 1998;77(1):87–94.CrossRefPubMed Falconer C, Blomgren B, Johansson O, Ulmsten U, Malmström A, Westergren-Thorsson G, et al. Different organization of collagen fibrils in stress-incontinent women of fertile age. Acta Obstet Gynecol Scand. 1998;77(1):87–94.CrossRefPubMed
8.
Zurück zum Zitat Vereecken RL. A critical view on the value of urodynamics in non-neurogenic incontinence in women. Int Urogynecol J. 2000;11(3):188–95.CrossRef Vereecken RL. A critical view on the value of urodynamics in non-neurogenic incontinence in women. Int Urogynecol J. 2000;11(3):188–95.CrossRef
9.
Zurück zum Zitat Lose G, Thyssen H. Reproducibility of cystometry and pressure-flow parameters in female patients. Neurourol Urodyn. 1996;15:302–3. Lose G, Thyssen H. Reproducibility of cystometry and pressure-flow parameters in female patients. Neurourol Urodyn. 1996;15:302–3.
10.
Zurück zum Zitat Versi E. Discriminant analysis of urethral pressure profilometry data for the diagnosis of genuine stress incontinence. BJOG. 1990;97(3):251–9.CrossRef Versi E. Discriminant analysis of urethral pressure profilometry data for the diagnosis of genuine stress incontinence. BJOG. 1990;97(3):251–9.CrossRef
11.
Zurück zum Zitat Garra BS, Cespedes EI, Ophir J, Spratt SR, Zuurbier RA, Magnant CM, et al. Elastography of breast lesions: initial clinical results. Radiology. 1997;202(1):79–86.CrossRefPubMed Garra BS, Cespedes EI, Ophir J, Spratt SR, Zuurbier RA, Magnant CM, et al. Elastography of breast lesions: initial clinical results. Radiology. 1997;202(1):79–86.CrossRefPubMed
12.
Zurück zum Zitat Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T, et al. Breast disease: clinical application of us elastography for diagnosis. Radiology. 2006;239(2):341–50.CrossRefPubMed Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T, et al. Breast disease: clinical application of us elastography for diagnosis. Radiology. 2006;239(2):341–50.CrossRefPubMed
13.
Zurück zum Zitat Zhi H, Ou B, Luo BM, Feng X, Wen YL, Yang HY. Comparison of ultrasound elastography, mammography, and sonography in the diagnosis of solid breast lesions. J Ultrasound Med. 2007;26(6):807–15.CrossRefPubMed Zhi H, Ou B, Luo BM, Feng X, Wen YL, Yang HY. Comparison of ultrasound elastography, mammography, and sonography in the diagnosis of solid breast lesions. J Ultrasound Med. 2007;26(6):807–15.CrossRefPubMed
14.
Zurück zum Zitat Sandrin L, Fourquet B, Hasquenoph JM, Yon S, Fournier C, Mal F, et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol. 2003;29(12):1705–13.CrossRefPubMed Sandrin L, Fourquet B, Hasquenoph JM, Yon S, Fournier C, Mal F, et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol. 2003;29(12):1705–13.CrossRefPubMed
15.
Zurück zum Zitat Von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. Strobe initiative. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Prev Med. 2007;45(4):247–51.CrossRef Von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. Strobe initiative. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Prev Med. 2007;45(4):247–51.CrossRef
16.
Zurück zum Zitat Hvarness H, Skjoldbye B, Jakobsen H. Urinary bladder volume measurements: comparison of three ultrasound calculation methods. Scand J Urol Nephrol. 2002;36(3):177–81.CrossRefPubMed Hvarness H, Skjoldbye B, Jakobsen H. Urinary bladder volume measurements: comparison of three ultrasound calculation methods. Scand J Urol Nephrol. 2002;36(3):177–81.CrossRefPubMed
17.
Zurück zum Zitat Tzankoff SP, Norris AH. Effect of muscle mass decrease on age-related BMR changes. J Appl Physiol. 1977;43(6):1001–6.PubMed Tzankoff SP, Norris AH. Effect of muscle mass decrease on age-related BMR changes. J Appl Physiol. 1977;43(6):1001–6.PubMed
18.
Zurück zum Zitat Jensen JK, Nielsen Jr FR, Ostergard DR. The role of patient history in the diagnosis of urinary incontinence. Obstet Gynecol. 1994;83:904.PubMed Jensen JK, Nielsen Jr FR, Ostergard DR. The role of patient history in the diagnosis of urinary incontinence. Obstet Gynecol. 1994;83:904.PubMed
19.
20.
Zurück zum Zitat Taylor LS. Three-dimensional sonoelastography: principles and practices with application to tumor visualization and volume estimation. 2002. Rochester, NY: University of Rochester. Department of Electrical and Computer Engineering Taylor LS. Three-dimensional sonoelastography: principles and practices with application to tumor visualization and volume estimation. 2002. Rochester, NY: University of Rochester. Department of Electrical and Computer Engineering
21.
Zurück zum Zitat Nightingale K, McAleavey S, Trahey G. Shear-wave generation using acoustic radiation force: in vivo and ex vivo results. Ultrasound Med Biol. 2003;29(12):1715–23.CrossRefPubMed Nightingale K, McAleavey S, Trahey G. Shear-wave generation using acoustic radiation force: in vivo and ex vivo results. Ultrasound Med Biol. 2003;29(12):1715–23.CrossRefPubMed
22.
Zurück zum Zitat Yamaguchi T. The quantitative ultrasound diagnosis of liver fibrosis using statistical analysis of the echo envelope. In: Quantitative ultrasound in soft tissues. Netherlands: Springer; 2013. p. 275–28. Yamaguchi T. The quantitative ultrasound diagnosis of liver fibrosis using statistical analysis of the echo envelope. In: Quantitative ultrasound in soft tissues. Netherlands: Springer; 2013. p. 275–28.
23.
Zurück zum Zitat Yoon JH, Kim MH, Kim EK, Moon HJ, Kwak JY, Kim MJ. Interobserver variability of ultrasound elastography: how it affects the diagnosis of breast lesions. Am J Roentgenol. 2011;196(3):730–6.CrossRef Yoon JH, Kim MH, Kim EK, Moon HJ, Kwak JY, Kim MJ. Interobserver variability of ultrasound elastography: how it affects the diagnosis of breast lesions. Am J Roentgenol. 2011;196(3):730–6.CrossRef
24.
Zurück zum Zitat Morikawa H. Real-time tissue elastography and transient elastography for evaluation of hepatic fibrosis. Rijeka: INTECH Open Access Publisher; 2012.CrossRef Morikawa H. Real-time tissue elastography and transient elastography for evaluation of hepatic fibrosis. Rijeka: INTECH Open Access Publisher; 2012.CrossRef
25.
Zurück zum Zitat Salomon G, Köllerman J, Thederan I, Chun FK, Budäus L, Schlomm T, et al. Evaluation of prostate cancer detection with ultrasound real-time elastography: a comparison with step section pathological analysis after radical prostatectomy. Eur Urol. 2008;54(6):1354–62.CrossRefPubMed Salomon G, Köllerman J, Thederan I, Chun FK, Budäus L, Schlomm T, et al. Evaluation of prostate cancer detection with ultrasound real-time elastography: a comparison with step section pathological analysis after radical prostatectomy. Eur Urol. 2008;54(6):1354–62.CrossRefPubMed
26.
Zurück zum Zitat Ying H, Da L, Luo J, Li-Xia L, Yu X, Li-Mei X, et al. Quantitative assessment of bladder neck compliance by using transvaginal real-time elastography of women. Ultrasound Med Biol. 2013;39(10):1727–34.CrossRefPubMed Ying H, Da L, Luo J, Li-Xia L, Yu X, Li-Mei X, et al. Quantitative assessment of bladder neck compliance by using transvaginal real-time elastography of women. Ultrasound Med Biol. 2013;39(10):1727–34.CrossRefPubMed
27.
Zurück zum Zitat Hall TJ, Zhu Y, Spalding CS. In vivo real-time freehand palpation imaging. Ultrasound Med Biol. 2003;29(3):427–35.CrossRefPubMed Hall TJ, Zhu Y, Spalding CS. In vivo real-time freehand palpation imaging. Ultrasound Med Biol. 2003;29(3):427–35.CrossRefPubMed
28.
Zurück zum Zitat Bruschini H, Simonetti R, Antunes AA, Srougi M. Urinary incontinence following surgery for BPH: the role of aging on the incidence of bladder dysfunction. Int Braz J Urol. 2011;37(3):380–7.CrossRefPubMed Bruschini H, Simonetti R, Antunes AA, Srougi M. Urinary incontinence following surgery for BPH: the role of aging on the incidence of bladder dysfunction. Int Braz J Urol. 2011;37(3):380–7.CrossRefPubMed
29.
Zurück zum Zitat Meyer S, Schreyer A, De Grandi P, Hohlfeld P. The effects of birth on urinary continence mechanisms and other pelvic-floor characteristics. Obstet Gynecol. 1998;92(4, Part 1):613–8.PubMed Meyer S, Schreyer A, De Grandi P, Hohlfeld P. The effects of birth on urinary continence mechanisms and other pelvic-floor characteristics. Obstet Gynecol. 1998;92(4, Part 1):613–8.PubMed
Metadaten
Titel
Trans-abdominal ultrasound shear wave elastographyfor quantitative assessment of female bladder neck elasticity
verfasst von
David Sheyn
Yasmine Ahmed
Nami Azar
Sherif El-Nashar
Adonis Hijaz
Sangeeta Mahajan
Publikationsdatum
14.11.2016
Verlag
Springer London
Erschienen in
International Urogynecology Journal / Ausgabe 5/2017
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-016-3193-3

Weitere Artikel der Ausgabe 5/2017

International Urogynecology Journal 5/2017 Zur Ausgabe

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.