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Erschienen in: International Journal of Colorectal Disease 1/2019

12.11.2018 | Review

Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials

verfasst von: Sameh Hany Emile, Hossam Elfeki, Ahmad Sakr, Mostafa Shalaby

Erschienen in: International Journal of Colorectal Disease | Ausgabe 1/2019

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Abstract

Background

Although conventional hemorrhoidectomy proved effective in treatment of hemorrhoidal disease, postoperative pain remains a vexing problem. Alternatives to conventional hemorrhoidectomy as transanal hemorrhoidal dearterialization (THD) and stapled hemorrhoidopexy (SH) were described. The present meta-analysis aimed to review the randomized trials that compared THD and SH to determine which technique is superior in terms of recurrence of hemorrhoids, complications, and postoperative pain.

Methods

Electronic databases were searched for randomized trials that compared THD and SH for internal hemorrhoids. The PRISMA guidelines were followed when reporting this meta-analysis. The primary endpoint of the analysis was persistence or recurrence of hemorrhoidal disease. Secondary endpoints were postoperative pain, complications, readmission, return to work, and patients’ satisfaction.

Results

Six randomized trials including 554 patients (THD = 280; SH = 274) were included. The mean postoperative pain score of THD was significantly lower than SH (2.9 ± 1.5 versus 3.3 ± 1.6). 13.2% of patients experienced persistent or recurrent hemorrhoids after THD versus 6.9% after SH (OR = 1.93, 95%CI = 1.07–3.51, p = 0.029). Complications were recorded in 17.1% of patients who underwent THD and 23.3% of patients who underwent SH (OR = 0.68, 95%CI 0.43–1.05, p = 0.08). The average duration to return to work after THD was 7.3 ± 5.2 versus 7.7 ± 4.8 days after SH (p = 0.34). Grade IV hemorrhoids was significantly associated with persistence or recurrence of hemorrhoidal disease after both procedures.

Conclusion

THD had significantly higher persistence/recurrence rate compared to SH whereas complication and readmission rates, hospital stay, return to work, and patients’ satisfaction were similar in both groups.
Literatur
2.
Zurück zum Zitat American Gastroenterological Association medical position statement (2004) Diagnosis and treatment of hemorrhoids. Gastroenterology 126(5):1461–1462CrossRef American Gastroenterological Association medical position statement (2004) Diagnosis and treatment of hemorrhoids. Gastroenterology 126(5):1461–1462CrossRef
3.
Zurück zum Zitat Rivadeneira DE, Steele SR, Ternent C et al (2011) Practice parameters for the management of hemorrhoids (revised 2010). Dis Colon Rectum 54(9):1059–1064CrossRefPubMed Rivadeneira DE, Steele SR, Ternent C et al (2011) Practice parameters for the management of hemorrhoids (revised 2010). Dis Colon Rectum 54(9):1059–1064CrossRefPubMed
4.
Zurück zum Zitat Hollingshead JR, Phillips RK (2016) Haemorrhoids: modern diagnosis and treatment. Postgrad Med J 92(1083):4–8CrossRefPubMed Hollingshead JR, Phillips RK (2016) Haemorrhoids: modern diagnosis and treatment. Postgrad Med J 92(1083):4–8CrossRefPubMed
5.
Zurück zum Zitat Raahave D, Jepsen LV, Pedersen IK (2008) Primary and repeated stapled hemorrhoidopexy for prolapsing hemorrhoids: follow-up to five years. Dis Colon Rectum 51(3):334–341CrossRefPubMed Raahave D, Jepsen LV, Pedersen IK (2008) Primary and repeated stapled hemorrhoidopexy for prolapsing hemorrhoids: follow-up to five years. Dis Colon Rectum 51(3):334–341CrossRefPubMed
6.
Zurück zum Zitat Ratto C, Parello A, Veronese E, Cudazzo E, D'Agostino E, Pagano C, Cavazzoni E, Brugnano L, Litta F (2015) Doppler-guided transanal haemorrhoidal dearterialization for haemorrhoids: results from a multicentre trial. Color Dis 17(1):O10–O19CrossRef Ratto C, Parello A, Veronese E, Cudazzo E, D'Agostino E, Pagano C, Cavazzoni E, Brugnano L, Litta F (2015) Doppler-guided transanal haemorrhoidal dearterialization for haemorrhoids: results from a multicentre trial. Color Dis 17(1):O10–O19CrossRef
7.
Zurück zum Zitat Scheyer M, Antonietti E, Rollinger G, Lancee S, Pokorny H (2015) Hemorrhoidal artery ligation (HAL) and rectoanal repair (RAR): retrospective analysis of 408 patients in a single center. Tech Coloproctol 19(1):5–9CrossRefPubMed Scheyer M, Antonietti E, Rollinger G, Lancee S, Pokorny H (2015) Hemorrhoidal artery ligation (HAL) and rectoanal repair (RAR): retrospective analysis of 408 patients in a single center. Tech Coloproctol 19(1):5–9CrossRefPubMed
8.
Zurück zum Zitat Longo A (2002) Stapled anopexy and stapled hemorrhoidectomy: two opposite concepts and procedures. Dis Colon Rectum 45(4):571–572CrossRefPubMed Longo A (2002) Stapled anopexy and stapled hemorrhoidectomy: two opposite concepts and procedures. Dis Colon Rectum 45(4):571–572CrossRefPubMed
10.
Zurück zum Zitat Sohn N, Aronoff JS, Cohen FS, Weinstein MA (2001) Transanal hemorrhoidal dearterialization is an alternative to operative hemorrhoidectomy. Am J Surg 182(5):515–519CrossRefPubMed Sohn N, Aronoff JS, Cohen FS, Weinstein MA (2001) Transanal hemorrhoidal dearterialization is an alternative to operative hemorrhoidectomy. Am J Surg 182(5):515–519CrossRefPubMed
11.
Zurück zum Zitat Dal Monte PP, Tagariello C, Sarago M, Giordano P, Shafi A, Cudazzo E et al (2007) Transanal haemorrhoidal dearterialisation: nonexcisional surgery for the treatment of haemorrhoidal disease. Tech Coloproctol 11(4):333–338CrossRefPubMed Dal Monte PP, Tagariello C, Sarago M, Giordano P, Shafi A, Cudazzo E et al (2007) Transanal haemorrhoidal dearterialisation: nonexcisional surgery for the treatment of haemorrhoidal disease. Tech Coloproctol 11(4):333–338CrossRefPubMed
13.
Zurück zum Zitat Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700CrossRefPubMedPubMedCentral Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA, Cochrane Bias Methods Group, Cochrane Statistical Methods Group (2011) The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 343:d5928CrossRefPubMedPubMedCentral Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA, Cochrane Bias Methods Group, Cochrane Statistical Methods Group (2011) The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 343:d5928CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Infantino A, Altomare DF, Bottini C, Bonanno M, Mancini S, THD group of the SICCR (Italian Society of Colorectal Surgery), Yalti T, Giamundo P, Hoch J, El Gaddal A, Pagano C (2012) Prospective randomized multicentre study comparing stapler haemorrhoidopexy with Doppler-guided transanal haemorrhoid dearterialization for third-degree haemorrhoids. Color Dis 14(2):205–211. https://doi.org/10.1111/j.1463-1318.2011.02628.x. CrossRef Infantino A, Altomare DF, Bottini C, Bonanno M, Mancini S, THD group of the SICCR (Italian Society of Colorectal Surgery), Yalti T, Giamundo P, Hoch J, El Gaddal A, Pagano C (2012) Prospective randomized multicentre study comparing stapler haemorrhoidopexy with Doppler-guided transanal haemorrhoid dearterialization for third-degree haemorrhoids. Color Dis 14(2):205–211. https://​doi.​org/​10.​1111/​j.​1463-1318.​2011.​02628.​x.​ CrossRef
18.
Zurück zum Zitat Verre L, Rossi R, Gaggelli I, Di Bella C, Tirone A, Piccolomini A (2013) PPH versus THD: a comparison of two techniques for III and IV degree haemorrhoids. Personal experience. Minerva Chir 68(6):543–550PubMed Verre L, Rossi R, Gaggelli I, Di Bella C, Tirone A, Piccolomini A (2013) PPH versus THD: a comparison of two techniques for III and IV degree haemorrhoids. Personal experience. Minerva Chir 68(6):543–550PubMed
19.
Zurück zum Zitat Venturi M, Salamina G, Vergani C (2016) Stapled anopexy versus transanal hemorrhoidal dearterialization for hemorrhoidal disease: a three-year follow-up from a randomized study. Minerva Chir 71(6):365–371PubMed Venturi M, Salamina G, Vergani C (2016) Stapled anopexy versus transanal hemorrhoidal dearterialization for hemorrhoidal disease: a three-year follow-up from a randomized study. Minerva Chir 71(6):365–371PubMed
20.
24.
Zurück zum Zitat Jayaraman S, Colquhoun PH, Malthaner RA (2007) Stapled hemorrhoidopexy is associated with a higher long-term recurrence rate of internal hemorrhoids compared with conventional excisional hemorrhoid surgery. Dis Colon Rectum 50(9):1297–1305CrossRefPubMed Jayaraman S, Colquhoun PH, Malthaner RA (2007) Stapled hemorrhoidopexy is associated with a higher long-term recurrence rate of internal hemorrhoids compared with conventional excisional hemorrhoid surgery. Dis Colon Rectum 50(9):1297–1305CrossRefPubMed
25.
Zurück zum Zitat Xu L, Chen H, Lin G, Ge Q, Qi H, He X (2016) Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Tech Coloproctol 20(12):825–833CrossRefPubMed Xu L, Chen H, Lin G, Ge Q, Qi H, He X (2016) Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Tech Coloproctol 20(12):825–833CrossRefPubMed
27.
28.
29.
Zurück zum Zitat Khubchandani I, Fealk MH, Reed JF 3rd (2009) Is there a post-PPH syndrome? Tech Coloproctol 13(2):141–144CrossRefPubMed Khubchandani I, Fealk MH, Reed JF 3rd (2009) Is there a post-PPH syndrome? Tech Coloproctol 13(2):141–144CrossRefPubMed
30.
Zurück zum Zitat Pescatori M, Gagliardi G (2008) Postoperative complications after procedure for prolapsed haemorrhoids (PPH) and stapled transanal rectal resection (STARR) procedures. Tech Coloproctol 12(1):7–19CrossRefPubMedPubMedCentral Pescatori M, Gagliardi G (2008) Postoperative complications after procedure for prolapsed haemorrhoids (PPH) and stapled transanal rectal resection (STARR) procedures. Tech Coloproctol 12(1):7–19CrossRefPubMedPubMedCentral
32.
Zurück zum Zitat Zaheer S, Reilly WT, Pemberton JH et al (1998) Urinary retention after operations for benign anorectal diseases. Dis Colon Rectum 41:696–704CrossRefPubMed Zaheer S, Reilly WT, Pemberton JH et al (1998) Urinary retention after operations for benign anorectal diseases. Dis Colon Rectum 41:696–704CrossRefPubMed
33.
Zurück zum Zitat De Santis G, Gola P, Lancione L, Sista F, Pietroletti R, Leardi S (2012) Sigmoid intramural hematoma and hemoperitoneum: an early severe complication after stapled hemorrhoidopexy. Tech Coloproctol 16:315–317CrossRefPubMed De Santis G, Gola P, Lancione L, Sista F, Pietroletti R, Leardi S (2012) Sigmoid intramural hematoma and hemoperitoneum: an early severe complication after stapled hemorrhoidopexy. Tech Coloproctol 16:315–317CrossRefPubMed
34.
Zurück zum Zitat Pescatori M, Spyrou M, Cobellis L, Bottini C, Tessera G (2006) The rectal pocket syndrome after stapled mucosectomy. Color Dis 8(9):808–811CrossRef Pescatori M, Spyrou M, Cobellis L, Bottini C, Tessera G (2006) The rectal pocket syndrome after stapled mucosectomy. Color Dis 8(9):808–811CrossRef
35.
Zurück zum Zitat George R, Vivek S, Suprej K (2016) How long to stay in hospital: stapled versus open hemorrhoidectomy? Saudi Surg J 4:108–112CrossRef George R, Vivek S, Suprej K (2016) How long to stay in hospital: stapled versus open hemorrhoidectomy? Saudi Surg J 4:108–112CrossRef
37.
Zurück zum Zitat Laughlan K, Jayne DG, Jackson D, Rupprecht F, Ribaric G (2009) Stapled haemorrhoidopexy compared to Milligan Morgan and Ferguson haemorrhoidectomy: a systemic review. Int J Colorectal 24:335–344CrossRef Laughlan K, Jayne DG, Jackson D, Rupprecht F, Ribaric G (2009) Stapled haemorrhoidopexy compared to Milligan Morgan and Ferguson haemorrhoidectomy: a systemic review. Int J Colorectal 24:335–344CrossRef
38.
Zurück zum Zitat Ganio E, Altomare DF, Milito G, Gabrielli F, Canuti S (2007) Long-term outcome of a multicentre randomized clinical trial of stapled haemorrhoidopexy versus Milligan Morgan haemorroidectomy. Br J Surg 94:1033–1037CrossRefPubMed Ganio E, Altomare DF, Milito G, Gabrielli F, Canuti S (2007) Long-term outcome of a multicentre randomized clinical trial of stapled haemorrhoidopexy versus Milligan Morgan haemorroidectomy. Br J Surg 94:1033–1037CrossRefPubMed
Metadaten
Titel
Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials
verfasst von
Sameh Hany Emile
Hossam Elfeki
Ahmad Sakr
Mostafa Shalaby
Publikationsdatum
12.11.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
International Journal of Colorectal Disease / Ausgabe 1/2019
Print ISSN: 0179-1958
Elektronische ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-018-3187-3

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