Transient global amnesia like syndrome associated with acute infarction of the corpus callosum: a case report

Excerpt

The corpus callosum (CC) constitutes the largest white matter bundle and it connects the two cerebral hemispheres [1]. Infarction of the CC is rare. The clinical picture varies from an acute onset to slow evolving symptoms, frequently with poor localizing signs; however, the location of the infarct in the callosum often correlates with a specific etiology [2]. In previous studies, lesions in the CC caused permanent, but not transient global amnesia (TGA) by involving the thalamocortical portion of the Papez’ circuit. We present a patient with TGA like syndrome after a corpus callosum infarct to highlight its involvement in cognitive impairments. We discuss the pathophysiology of this rare entity and the more important clinical symptomatologies. …