Transjugular liver biopsy in severe alcoholic hepatitis
- 03.01.2017
- Original Article
Erschienen in:
- Verfasst von
- Shiran Shetty
- L Venkatakrishnan
- J Krishanveni
- Shantha Kumari
- Erschienen in
- Indian Journal of Gastroenterology | Ausgabe 1/2017
Abstract
Background
Alcoholic hepatitis and cirrhosis although part of spectrum of alcoholic liver disease can have overlapping features, and differentiating them using clinical, biochemical, and imaging features is not always possible. Standard therapy for each differs, and steroid therapy while beneficial in alcoholic hepatitis may be detrimental in cirrhosis due to high infectious complications. We analyzed our experience with liver biopsy in patients with severe alcoholic hepatitis.
Methods
Male patients in the age group of 25–65 years who were clinically diagnosed with severe alcoholic hepatitis (DF > 32) were retrospectively analyzed and included in this study. All of them had undergone transjugular liver biopsy within the first 7 days of hospitalization.
Results
Thirty patients were included. Most were in the 35–55 age group. Jaundice was present in all patients with fever and tender hepatomegaly also being common. On histopathological evaluation, 33.3% (n = 10) suspected clinically to have alcoholic hepatitis had underlying cirrhosis.
Conclusion
Cirrhosis is found in one third of patients with severe alcoholic hepatitis. This may alter our approach to management of this condition.
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- Titel
- Transjugular liver biopsy in severe alcoholic hepatitis
- Verfasst von
-
Shiran Shetty
L Venkatakrishnan
J Krishanveni
Shantha Kumari
- Publikationsdatum
- 03.01.2017
- Verlag
- Springer India
- Erschienen in
-
Indian Journal of Gastroenterology / Ausgabe 1/2017
Print ISSN: 0254-8860
Elektronische ISSN: 0975-0711 - DOI
- https://doi.org/10.1007/s12664-016-0720-6
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