Ausgabe 3/2025
Inhalt (36 Artikel)
Tenecteplase Plus Butyphthalide for Stroke Within 4.5–6 Hours of Onset (EXIT-BT): a Phase 2 Study
- Research
Hui-Sheng Chen, Ming-Rui Chen, Yu Cui, Xin-Yu Shen, Hong Zhang, Jiang Lu, Li-Wei Zhao, Ying-Jie Duan, Jing Li, Ya-Mei Wang, Lian-Qiu Min, Li-Hong Zhao, Li-Shu Wan, Zai-Hui Zhang, Thanh N. Nguyen
Angiotensin II Type 2 Receptor Agonism Alleviates Progressive Post-stroke Cognitive Impairment in Aged Spontaneously Hypertensive Rats
- Research
Abdulkarim Alshammari, Bindu Pillai, Pradip Kamat, Timothy W. Jones, Asamoah Bosomtwi, Mohammad Badruzzaman Khan, David C. Hess, Weiguo Li, Payaningal R. Somanath, Mohammed A. Sayed, Adviye Ergul, Susan C. Fagan
Remote Ischemic Post-conditioning Reduces Cognitive Impairment in Rats Following Subarachnoid Hemorrhage: Possible Involvement in STAT3/STAT5 Phosphorylation and Th17/Treg Cell Homeostasis
- Research
Yajun Zhu, Xiaoguo Li, DaoChen Wen, Zichao Huang, Jin Yan, Zhaosi Zhang, Yingwen Wang, Zongduo Guo
Cerebral Perfusion Characteristics and Dynamic Brain Structural Changes in Stroke-Prone Renovascular Hypertensive Rats: A Preclinical Model for Cerebral Small Vessel Disease
- Research
Xiangming Xu, Chi Xiao, Ming Yi, Jing Yang, Mengshi Liao, Kun Zhou, Liuting Hu, Fubing Ouyang, Linfang Lan, Yuhua Fan
GPR39 Agonist TC-G 1008 Promoted Mitochondrial Biogenesis and Improved Antioxidative Capability via CREB/PGC-1α Pathway Following Intracerebral Hemorrhage in Mice
- Research
Zhongyi Zhang, Ye Yuan, Xingyu Zhang, Lingui Gu, Yuguang Tang, Yutong Zhao, Jinyu Dai, Yihao Tao, Zongyi Xie
Experimental Ischemic Stroke Induces Secondary Bihemispheric White Matter Degeneration and Long-Term Cognitive Impairment
- Research
Ran Liu, Raymond Berry, Linshu Wang, Kiran Chaudhari, Ali Winters, Yuanhong Sun, Claire Caballero, Hannah Ampofo, Yiwei Shi, Bibek Thata, Luis Colon-Perez, Nathalie Sumien, Shao-Hua Yang
Development of a 3D Brain Model to Study Sex-Specific Neuroinflammation After Hemorrhagic Stroke
- Open Access
- Research
Rezwanul Islam, Hadi Hasan Choudhary, Hritik Mehta, Feng Zhang, Tudor G. Jovin, Khalid A. Hanafy
Depth-Specific Hypoxic Responses to Spreading Depolarizations in Gyrencephalic Swine Cortex Unveiled by Photoacoustic Imaging
- Research
Edgar Santos, Juan M. Lopez-Navarro, Marcos Alejandro Suarez-Gutierrez, Niklas Holzwarth, Pablo Albiña-Palmarola, Thomas Kirchner, Adrian Hernandez-Aguilera, Jose Antonio Fernandez-Amador, Farzam Vazifehdan, Johannes Woitzik, Lena Maier-Hein, Renan Sanchez-Porras
Association of Genetic Variants with Postoperative Donor Artery Development in Moyamoya Disease: RNF213 and Other Moyamoya Angiopathy-Related Gene Analysis
- Open Access
- Research
Seiei Torazawa, Satoru Miyawaki, Hideaki Imai, Hiroki Hongo, Hideaki Ono, Shotaro Ogawa, Yu Sakai, Satoshi Kiyofuji, Satoshi Koizumi, Daisuke Komura, Hiroto Katoh, Shumpei Ishikawa, Nobuhito Saito
Glymphatic Impairment Associated with Neurocognitive Dysfunction in Moyamoya Disease
- Research
Chaofan Zeng, Yuanren Zhai, Peicong Ge, Chenglong Liu, Xiaofan Yu, Wei Liu, Junsheng Li, Qiheng He, Xingju Liu, Xun Ye, Qian Zhang, Rong Wang, Yan Zhang, Dong Zhang, Jizong Zhao
Flow-Diverting Devices in the Treatment of Vertebral Artery Aneurysms: Insights into Efficacy and Safety from a Systematic Review and Meta-analysis
- Research
Changya Liu, Xinxin Wu, Kaikai Guo, Yuting Sun, Cai Yike, Xuebin Hu, Bangjiang Fang
Blood DNA Methylation Analysis Reveals a Distinctive Epigenetic Signature of Vasospasm in Aneurysmal Subarachnoid Hemorrhage
- Research
Isabel Fernández-Pérez, Joan Jiménez-Balado, Adrià Macias-Gómez, Antoni Suárez‑Pérez, Marta Vallverdú-Prats, Alberto Pérez-Giraldo, Marc Viles-García, Julia Peris-Subiza, Sergio Vidal-Notari, Eva Giralt-Steinhauer, Daniel Guisado-Alonso, Manel Esteller, Ana Rodriguez-Campello, Jordi Jiménez-Conde, Angel Ois, Elisa Cuadrado-Godia
Haptoglobin Attenuates Cerebrospinal Fluid Hemoglobin-Induced Neurological Deterioration in Sheep
- Open Access
- Research
Bart R. Thomson, Nina Schwendinger, Katrin Beckmann, Thomas Gentinetta, Daniel Couto, Sandra Wymann, Valérie Verdon, Raphael M. Buzzi, Kevin Akeret, Peter W. Kronen, Eva M. Weinberger, Ulrike Held, Frauke Seehusen, Henning Richter, Dominik J. Schaer, Michael Hugelshofer
Integrating Bulk RNA and Single-Cell Sequencing Data Unveils Efferocytosis Patterns and ceRNA Network in Ischemic Stroke
- Research
Jing Yuan, Yu-sha Liao, Tie-chun Zhang, Yu-qi Tang, Pei Yu, Ya-ning Liu, Ding-jun Cai, Shu-guang Yu, Ling Zhao
Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS
- Research
Zsuzsanna Ament, Amit Patki, Varun M. Bhave, Naruchorn Kijpaisalratana, Alana C. Jones, Catharine A. Couch, Robert J. Stanton, Pamela M. Rist, Mary Cushman, Suzanne E. Judd, D. Leann Long, M. Ryan Irvin, W. Taylor Kimberly
Unveiling the Hidden Impact: Hematoma Volumes Unravel Circuit Disruptions in Intracerebral Hemorrhage
- Research
Yingqing Wu, Qin Deng, Ranran Wei, Sen Chen, Fusheng Ding, Haipeng Yu, Ning Hu, Shilei Hao, Bochu Wang
Reporting Compliance and Factors Influencing Timeliness of Stroke-Related Trial Results on ClinicalTrials.gov
- Research
Mark Cwajna, Abdelrahman M. Hamouda, Nicholas Kendall, Sherief Ghozy, Benjamin D. Elder, David F. Kallmes
The Impact of VEGF-C-Induced Dural Lymphatic Vessel Growth on Ischemic Stroke Pathology
- Open Access
- Research
Meike Hedwig Keuters, Salli Antila, Riikka Immonen, Lidiia Plotnikova, Sara Wojciechowski, Sarka Lehtonen, Kari Alitalo, Jari Koistinaho, Hiramani Dhungana
Single-Cell Transcriptomics Revealed White Matter Repair Following Subarachnoid Hemorrhage
- Research
Xing Wang, Dingke Wen, Fan Xia, Mei Fang, Jun Zheng, Chao You, Lu Ma
Extracellular Vesicles Obtained from Hypoxic Mesenchymal Stromal Cells Induce Neurological Recovery, Anti-inflammation, and Brain Remodeling After Distal Middle Cerebral Artery Occlusion in Rats
- Open Access
- Research
Mihaela Abuzan, Roxana Surugiu, Chen Wang, Ayan Mohamud-Yusuf, Tobias Tertel, Bogdan Catalin, Thorsten R. Doeppner, Bernd Giebel, Dirk M. Hermann, Aurel Popa-Wagner
Loss of Epitranscriptomic Modification N6-Methyladenosine (m6A) Reader YTHDF1 Exacerbates Ischemic Brain Injury in a Sexually Dimorphic Manner
- Research
Anil K. Chokkalla, Vijay Arruri, Suresh L. Mehta, Raghu Vemuganti
Cerebral [18F]AIF-FAPI-42-Based PET Imaging of Fibroblast Activation Protein for Non-invasive Quantification of Fibrosis After Ischemic Stroke
- Research
Peipei Tang, Yang Liu, Simin Peng, Zhikai Cai, Ganghua Tang, Zhou Zhou, Kongzhen Hu, Yuhua Zhong
Except for Robust Outliers, Rapamycin Increases Lesion Burden in a Murine Model of Cerebral Cavernous Malformations
- Research
Roberto J. Alcazar-Felix, Robert Shenkar, Christian R. Benavides, Akash Bindal, Abhinav Srinath, Ying Li, Serena Kinkade, Tatiana Terranova, Evon DeBose-Scarlett, Rhonda Lightle, Dorothy DeBiasse, Hanadi Almazroue, Diana Vera Cruz, Sharbel Romanos, Aditya Jhaveri, Janne Koskimäki, Stephanie Hage, Carolyn Bennett, Romuald Girard, Douglas A. Marchuk, Issam A. Awad
HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke
- Research
Haoran Lin, Yun Bei, Zexu Shen, Taofeng Wei, Yuyang Ge, Lingyan Yu, Huimin Xu, Wei He, Yunjian Dai, Difei Yao, Haibin Dai
Complement Inhibition Reduces Early Erythrolysis, Attenuates Brain Injury, Hydrocephalus, and Iron Accumulation after Intraventricular Hemorrhage in Aged Rats
- Research
Tianjie Zhang, Fan Xia, Yingfeng Wan, Guohua Xi, Hua Ya, Richard F. Keep
Mesenchymal Stem Cell-Loaded Hydrogel Improves Surgical Treatment for Chronic Cerebral Ischemia
- Research
Huayu Kang, Yimin Huang, Huan Peng, Xincheng Zhang, Yuan Liu, Yanchao Liu, Yuze Xia, Shengwen Liu, Yaqi Wu, Sheng Wang, Ting Lei, Huaqiu Zhang
Evaluation of AAV Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy
- Research
Alka Yadav, Rich Liang, Kelly Press, Annika Schmidt, Zahra Shabani, Kun Leng, Calvin Wang, Abinav Sekhar, Joshua Shi, Garth W. Devlin, Trevor J. Gonzalez, Aravind Asokan, Hua Su
Cerebral Small Vessel Disease and Infarct Growth in Acute Ischemic Stroke Treated with Intravenous Thrombolysis
- Research
Francesco Arba, Simone Ferretti, Richard Leigh, Andreia Fara, Steven J Warach, Marie Luby, Kennedy R Lees, Jesse Dawson
Protease-Activated Receptors (PARs): Biology and Therapeutic Potential in Perioperative Stroke
- Review
Theodoros Mavridis, Theodora Choratta, Androniki Papadopoulou, Assaf Sawafta, Paraschos Archontakis-Barakakis, Eleni Laou, Minas Sakellakis, Athanasios Chalkias
Switching Off Vascular MAPK Signaling: A Novel Strategy to Prevent Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage
- Open Access
- Review
Lars Edvinsson, Diana N. Krause
Type I Interferon Signalling and Ischemic Stroke: Mechanisms and Therapeutic Potentials
- Review
Pan Cui, Bo Song, Zongping Xia, Yuming Xu
Evolving Therapeutic Landscape of Intracerebral Hemorrhage: Emerging Cutting-Edge Advancements in Surgical Robots, Regenerative Medicine, and Neurorehabilitation Techniques
- Open Access
- Review
Danyang Chen, Zhixian Zhao, Shenglun Zhang, Shiling Chen, Xuan Wu, Jian Shi, Na Liu, Chao Pan, Yingxin Tang, Cai Meng, Xingwei Zhao, Bo Tao, Wenjie Liu, Diansheng Chen, Han Ding, Ping Zhang, Zhouping Tang
HMGB1: A New Target for Ischemic Stroke and Hemorrhagic Transformation
- Open Access
- Review
Jiamin Li, Zixin Wang, Jiameng Li, Haiping Zhao, Qingfeng Ma
Imaging of Intracranial Aneurysms: A Review of Standard and Advanced Imaging Techniques
- Review
Sricharan S. Veeturi, Samuel Hall, Soichiro Fujimura, Mahmud Mossa-Basha, Elena Sagues, Edgar A. Samaniego, Vincent M. Tutino
Correction to: Comparison of Long‑Term Outcomes in Ruptured Diffuse Brain Arteriovenous Malformations Between Interventional Therapy and Conservative Management
- Author Correction
Changyu Lu, Heze Han, Li Ma, Ruinan Li, Zhipeng Li, Haibin Zhang, Kexin Yuan, Yukun Zhang, Anqi Li, Ke Wang, Yang Zhao, Weitao Jin, Dezhi Gao, Hengwei Jin, Xiangyu Meng, Debin Yan, Runting Li, Fa Lin, Qiang Hao, Hao Wang, Xun Ye, Shuai Kang, Jun Pu, Zhiyong Shi, Xiaofeng Chao, Zhengfeng Lin, Junlin Lu, Youxiang Li, Yuanli Zhao, Shibin Sun, Xiaolin Chen, Weiwei Chen, Yu Chen, Shuo Wang
Correction to: Angiotensin II Type 2 Receptor Agonism Alleviates Progressive Post‑stroke Cognitive Impairment in Aged Spontaneously Hypertensive Rats
- Author Correction
Abdulkarim Alshammari, Bindu Pillai, Pradip Kamat, Timothy W. Jones, Asamoah Bosomtwi, Mohammad Badruzzaman Khan, David C. Hess, Weiguo Li, Payaningal R. Somanath, Mohammed A Sayed, Adviye Ergul, Susan C. Fagan
