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Erschienen in: The International Journal of Cardiovascular Imaging 6/2017

02.02.2017 | Images in CV Applications

Transthyretin cardiac amyloid and aortic stenosis in the elderly, the role of nuclear imaging

verfasst von: Elisa Merli, Eleonora Del Giudice, Athanassios Antonopoulos, Gianadrea Amadei, Elisabetta Varani

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 6/2017

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Excerpt

Cardiac amyloidosis is an under recognised cause of heart failure in the elderly [1]. It is predominantly related to myocardial deposition of wild-type transthyretin protein (aTTR) causing a restrictive cardiomyopathy and it is associated with poor prognosis [2]. Radionuclide bone scan is able to detect transthyretin myocardial deposition. Moderate and intense captation by the myocardium has been demonstrated diagnostic without need of myocardial biopsy [3]. This tool has given us the possibility to expand the diagnosis of transthyretin cardiac amyloidosis. Data from post-mortem studies in unselected subjects indicate a prevalence of cardiac amyloidosis of 22–25% in subjects older than 80 years of age [4]. …
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Metadaten
Titel
Transthyretin cardiac amyloid and aortic stenosis in the elderly, the role of nuclear imaging
verfasst von
Elisa Merli
Eleonora Del Giudice
Athanassios Antonopoulos
Gianadrea Amadei
Elisabetta Varani
Publikationsdatum
02.02.2017
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe 6/2017
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-016-1060-4

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