Skip to main content
Erschienen in: Surgical Endoscopy 1/2018

01.07.2017

Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program

verfasst von: Basilio Pirrera, Vincenzo Alagna, Andrea Lucchi, Pierluigi Berti, Carlo Gabbianelli, Giacomo Martorelli, Lorella Mozzoni, Federico Ruggeri, Alessandro Ingardia, Giuseppe Nardi, Gianluca Garulli

Erschienen in: Surgical Endoscopy | Ausgabe 1/2018

Einloggen, um Zugang zu erhalten

Abstract

Aim

The enhanced recovery after surgery (ERAS) pathway and laparoscopic approach had been proven beneficial for patients and should now be considered as a standard of care in colorectal surgery. Multimodal analgesia is the gold standard in the ERAS program with the use of thoracic epidural analgesia (TEA). Few data are available on Transversus abdominis plane (TAP) blocks in laparoscopic colorectal surgery and ERAS pathway. The aim of this study is to evaluate the efficacy of TAP block compared to TEA in the management of postoperative pain and the impact on the recurrence of postoperative nausea, vomiting and ileus in laparoscopic colorectal surgery in the ERAS program.

Method

From October 2014 to October 2016, 182 patients underwent elective colon surgical interventions in enhanced recovery after surgery pathway. The patients were divided into two groups: Group 1 (n = 92) and Group 2 (n = 91) who received TEA and TAP block, respectively, with a standardized postoperative analgesic regimen consisting of regular 1 g of paracetamol every 8 h and a rescue dose with intravenous non-steroidal anti-inflammatory drugs infusion for both groups.

Results

No differences were observed in baseline patient characteristics, clinical variables and surgical procedures between the two groups, as well as in the postoperative complications rate (p = 0.515) in accordance with Clavien–Dindo classification, 90-day mortality (p = 0.319), hospital stay (p = 0.469) and 30-day readmission rate (p = 0.711). Patients in the TAP block group showed lower postoperative nausea and vomiting rates (p = 0.025), as well as lower ileus (p = 0.031) and paraesthesia rates (p = 0.024). No differences were found in urinary retention (p = 0.157). Despite the “opioid-free” analgesia protocol in the TAP block group, pain intensity was comparable between the two groups (p = 0.651).

Conclusion

TAP block combined with an opioid-sparing analgesia in the setting of the laparoscopic colorectal surgery and ERAS program is feasible and effective in postoperative pain control.
Literatur
1.
Zurück zum Zitat Green BL, Marshall HC, Collinson F, Quirke P, Guillou P, Jayne DG, Brown JM (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100:75–82CrossRefPubMed Green BL, Marshall HC, Collinson F, Quirke P, Guillou P, Jayne DG, Brown JM (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100:75–82CrossRefPubMed
2.
Zurück zum Zitat Bonjer HJ, Deijen CL, Abis GA, Cuesta MA, van der Pas MH, de Lange-de Klerk ES, Lacy AM, Bemelman WA, Andersson J, Angenete E, Rosenberg J, Fuerst A, Haglind E, COLOR II Study Group (2015) A randomized trial of laparoscopic versus open surgery for rectal cancer. N Engl J Med 372:1324–1332CrossRefPubMed Bonjer HJ, Deijen CL, Abis GA, Cuesta MA, van der Pas MH, de Lange-de Klerk ES, Lacy AM, Bemelman WA, Andersson J, Angenete E, Rosenberg J, Fuerst A, Haglind E, COLOR II Study Group (2015) A randomized trial of laparoscopic versus open surgery for rectal cancer. N Engl J Med 372:1324–1332CrossRefPubMed
3.
Zurück zum Zitat Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M (2014) Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 38(6):1531–1541CrossRefPubMed Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M (2014) Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 38(6):1531–1541CrossRefPubMed
4.
Zurück zum Zitat Varadhan KK, Neal KR, Dejong CH, Fearon KC, Ljungqvist O, Lobo DN (2010) The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29(4):434–440CrossRefPubMed Varadhan KK, Neal KR, Dejong CH, Fearon KC, Ljungqvist O, Lobo DN (2010) The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29(4):434–440CrossRefPubMed
5.
Zurück zum Zitat Roulin D, Donadini A, Gander S, Griesser AC, Blanc C, Hubner M et al (2013) Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 100(8):1108–1114CrossRefPubMed Roulin D, Donadini A, Gander S, Griesser AC, Blanc C, Hubner M et al (2013) Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 100(8):1108–1114CrossRefPubMed
6.
Zurück zum Zitat Fearon KC, Ljungqvist O, Von Meyenfeldt M et al (2005) Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:466–477CrossRefPubMed Fearon KC, Ljungqvist O, Von Meyenfeldt M et al (2005) Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:466–477CrossRefPubMed
7.
Zurück zum Zitat Kehlet H, Wilmore DW (2008) Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg 248(2):189–198CrossRefPubMed Kehlet H, Wilmore DW (2008) Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg 248(2):189–198CrossRefPubMed
8.
Zurück zum Zitat Kehlet H (1989) Surgical stress: the role of pain and analgesia. Br J Anaesth 63(2):189–195CrossRefPubMed Kehlet H (1989) Surgical stress: the role of pain and analgesia. Br J Anaesth 63(2):189–195CrossRefPubMed
9.
Zurück zum Zitat Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, McNaught CE, Macfie J, Liberman AS, Soop M, Hill A, Kennedy RH, Lobo DN, Fearon K, Ljungqvist O (2013) Enhanced Recovery After Surgery (ERAS) Society, for Perioperative Care; European Society for Clinical Nutrition and Metabolism (ESPEN); International Association for Surgical Metabolism and Nutrition (IASMEN). Guidelines for perioperative care in elective colonic surgery: enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg 37(2):259–284CrossRefPubMed Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, McNaught CE, Macfie J, Liberman AS, Soop M, Hill A, Kennedy RH, Lobo DN, Fearon K, Ljungqvist O (2013) Enhanced Recovery After Surgery (ERAS) Society, for Perioperative Care; European Society for Clinical Nutrition and Metabolism (ESPEN); International Association for Surgical Metabolism and Nutrition (IASMEN). Guidelines for perioperative care in elective colonic surgery: enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg 37(2):259–284CrossRefPubMed
10.
Zurück zum Zitat Basse L, Thorbøl JE, Løssl K, Kehlet H (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277CrossRefPubMed Basse L, Thorbøl JE, Løssl K, Kehlet H (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277CrossRefPubMed
11.
Zurück zum Zitat Levy BF, Scott MJ, Fawcett W, Fry C, Rockall TA (2011) Randomized clinical trial of epidural, spinal or patient-controlled analgesia for patients undergoing laparoscopic colorectal surgery. Br J Surg 98:1068–1078CrossRefPubMed Levy BF, Scott MJ, Fawcett W, Fry C, Rockall TA (2011) Randomized clinical trial of epidural, spinal or patient-controlled analgesia for patients undergoing laparoscopic colorectal surgery. Br J Surg 98:1068–1078CrossRefPubMed
12.
Zurück zum Zitat Hebbard P, Fujiwara Y, Shibata Y, Royse C (2007) Ultrasound guided transversus abdominis plane (TAP) block. Anaesth Intensive Care 35:616–617PubMed Hebbard P, Fujiwara Y, Shibata Y, Royse C (2007) Ultrasound guided transversus abdominis plane (TAP) block. Anaesth Intensive Care 35:616–617PubMed
13.
Zurück zum Zitat McDonnell JG, O’Donnell B, Curley G, Heffernan A, Power C, Laffey JG (2007) The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial. Anesth Analg 104:193–197CrossRefPubMed McDonnell JG, O’Donnell B, Curley G, Heffernan A, Power C, Laffey JG (2007) The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial. Anesth Analg 104:193–197CrossRefPubMed
14.
Zurück zum Zitat Rafi AN (2001) Abdominal field block: a new approach via the lumbar triangle. Anaesthesia 56:1024–1026CrossRefPubMed Rafi AN (2001) Abdominal field block: a new approach via the lumbar triangle. Anaesthesia 56:1024–1026CrossRefPubMed
15.
Zurück zum Zitat Jankovic ZB, du Feu FM, McConnell P (2009) An anatomical study of the transversus abdominis plane block: location of the lumbar triangle of Petit and adjacent nerves. Anesth Analg 109(3):981–985CrossRefPubMed Jankovic ZB, du Feu FM, McConnell P (2009) An anatomical study of the transversus abdominis plane block: location of the lumbar triangle of Petit and adjacent nerves. Anesth Analg 109(3):981–985CrossRefPubMed
16.
Zurück zum Zitat Zafar N, Davies R, Greenslade GL, Dixon AR (2010) The evolution of analgesia in an ‘accelerated’ recovery programme for resectional laparoscopic colorectal surgery with anastomosis. Colorectal Dis 12(2):119–124CrossRefPubMed Zafar N, Davies R, Greenslade GL, Dixon AR (2010) The evolution of analgesia in an ‘accelerated’ recovery programme for resectional laparoscopic colorectal surgery with anastomosis. Colorectal Dis 12(2):119–124CrossRefPubMed
17.
Zurück zum Zitat Bharti N, Kumar P, Bala I, Gupta V (2011) The efficacy of a novel approach to transversus abdominis plane block for postoperative analgesia after colorectal surgery. Anesth Analg 112(6):1504–1508CrossRefPubMed Bharti N, Kumar P, Bala I, Gupta V (2011) The efficacy of a novel approach to transversus abdominis plane block for postoperative analgesia after colorectal surgery. Anesth Analg 112(6):1504–1508CrossRefPubMed
18.
Zurück zum Zitat Conaghan P, Maxwell-Armstrong C, Bedforth N, Gornall C, Baxendale B, Hong LL, Carty HM, Acheson AG (2010) Efficacy of transversus abdominis plane blocks in laparoscopic colorectal resections. Surg Endosc 24(10):2480–2484CrossRefPubMed Conaghan P, Maxwell-Armstrong C, Bedforth N, Gornall C, Baxendale B, Hong LL, Carty HM, Acheson AG (2010) Efficacy of transversus abdominis plane blocks in laparoscopic colorectal resections. Surg Endosc 24(10):2480–2484CrossRefPubMed
19.
Zurück zum Zitat Favuzza J, Delaney CP (2013) Outcomes of discharge after elective laparoscopic colorectal surgery with transversus abdominis plane blocks and enhanced recovery pathway. J Am Coll Surg 217(3):503–506CrossRefPubMed Favuzza J, Delaney CP (2013) Outcomes of discharge after elective laparoscopic colorectal surgery with transversus abdominis plane blocks and enhanced recovery pathway. J Am Coll Surg 217(3):503–506CrossRefPubMed
20.
Zurück zum Zitat Pedrazzani C, Menestrina N, Moro M, Brazzo G, Mantovani G, Polati E, Guglielmi A (2016) Local wound infiltration plus transversus abdominis plane (TAP) block versus local wound infiltration in laparoscopic colorectal surgery and ERAS program. Surg Endosc 30:5117–5125CrossRefPubMed Pedrazzani C, Menestrina N, Moro M, Brazzo G, Mantovani G, Polati E, Guglielmi A (2016) Local wound infiltration plus transversus abdominis plane (TAP) block versus local wound infiltration in laparoscopic colorectal surgery and ERAS program. Surg Endosc 30:5117–5125CrossRefPubMed
21.
Zurück zum Zitat Delaney CP, Kehlet H, Senagore AJ, On behalf of the Postoperative Ileus Management Council (PIMC) (2006) Postoperative ileus: profiles, risk factors and definitions. A framework for optimizing surgical outcomes in patients undergoing major abdominal and colorectal surgery. Clin Consensus Update Gen Surg. http://www.clinicalwebcasts.com/pdfs/GenSurg_WEB.pdf Delaney CP, Kehlet H, Senagore AJ, On behalf of the Postoperative Ileus Management Council (PIMC) (2006) Postoperative ileus: profiles, risk factors and definitions. A framework for optimizing surgical outcomes in patients undergoing major abdominal and colorectal surgery. Clin Consensus Update Gen Surg. http://​www.​clinicalwebcasts​.​com/​pdfs/​GenSurg_​WEB.​pdf
22.
Zurück zum Zitat Spanjersberg WR, van Sambeeck JDP, Bremers A, Rosman C, van Laarhoven CJHM (2015) Systematic review and meta-analysis for laparoscopic versus open colon surgery with or without an ERAS programme. Surg Endosc 29(12):3443–3453CrossRefPubMedPubMedCentral Spanjersberg WR, van Sambeeck JDP, Bremers A, Rosman C, van Laarhoven CJHM (2015) Systematic review and meta-analysis for laparoscopic versus open colon surgery with or without an ERAS programme. Surg Endosc 29(12):3443–3453CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Hermanides J, Hollmann MW, Stevens MF, Lirk P (2012) Failed epidural: causes and management. Br J Anaesth 109(2):144–154CrossRefPubMed Hermanides J, Hollmann MW, Stevens MF, Lirk P (2012) Failed epidural: causes and management. Br J Anaesth 109(2):144–154CrossRefPubMed
25.
Zurück zum Zitat Jorgensen H, Wetterslev J, Moiniche S, Dahl JB. (2000) Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. Cochrane Database Syst Rev. (4):CD001893. doi:10.1002/14651858.CD001893 Jorgensen H, Wetterslev J, Moiniche S, Dahl JB. (2000) Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. Cochrane Database Syst Rev. (4):CD001893. doi:10.​1002/​14651858.​CD001893
26.
Zurück zum Zitat Keller DS, Ermlich BO, Schiltz N, Champagne BJ, Reynolds HL Jr, Stein SL, Delaney CP (2014) The effect of transverses abdominis plane blocks on postoperative pain in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial. Dis Colon Rectum 57:1290–1297CrossRefPubMed Keller DS, Ermlich BO, Schiltz N, Champagne BJ, Reynolds HL Jr, Stein SL, Delaney CP (2014) The effect of transverses abdominis plane blocks on postoperative pain in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial. Dis Colon Rectum 57:1290–1297CrossRefPubMed
27.
Zurück zum Zitat Walter CJ, Maxwell-Armstrong C, Pinkney TD, Conaghan PJ, Bedforth N, Gornall CB, Acheson AG (2013) A randomised controlled trial of the efficacy of ultrasound-guided transverses abdominis plane (TAP) block in laparoscopic colorectal surgery. Surg Endosc 27:2366–2372CrossRefPubMed Walter CJ, Maxwell-Armstrong C, Pinkney TD, Conaghan PJ, Bedforth N, Gornall CB, Acheson AG (2013) A randomised controlled trial of the efficacy of ultrasound-guided transverses abdominis plane (TAP) block in laparoscopic colorectal surgery. Surg Endosc 27:2366–2372CrossRefPubMed
28.
Zurück zum Zitat Keller DS, Ermlich BO, Delaney CP (2014) Demonstrating the benefits of transversus abdominis plane blocks on patient outcomes in laparoscopic colorectal surgery: review of 200 consecutive cases. J Am Coll Surg 219:1143–1148CrossRefPubMed Keller DS, Ermlich BO, Delaney CP (2014) Demonstrating the benefits of transversus abdominis plane blocks on patient outcomes in laparoscopic colorectal surgery: review of 200 consecutive cases. J Am Coll Surg 219:1143–1148CrossRefPubMed
29.
Zurück zum Zitat Favuzza J, Brady K, Delaney CP (2013) Transversus abdominis plane blocks and enhanced recovery pathways: making the 23-h hospital stay a realistic goal after laparoscopic colorectal surgery. Surg Endosc 27:2481–2486CrossRefPubMed Favuzza J, Brady K, Delaney CP (2013) Transversus abdominis plane blocks and enhanced recovery pathways: making the 23-h hospital stay a realistic goal after laparoscopic colorectal surgery. Surg Endosc 27:2481–2486CrossRefPubMed
31.
Zurück zum Zitat Oh TK, Yim J, Kim J, Eom W, Lee SA, Park SC, Oh JH, Park JW, Park B, Kim DH (2017) Effects of preoperative ultrasound-guided transversus abdominis plane block on pain after laparoscopic surgery for colorectal cancer: a double-blind randomized controlled trial. Surg Endosc 31:127–134CrossRefPubMed Oh TK, Yim J, Kim J, Eom W, Lee SA, Park SC, Oh JH, Park JW, Park B, Kim DH (2017) Effects of preoperative ultrasound-guided transversus abdominis plane block on pain after laparoscopic surgery for colorectal cancer: a double-blind randomized controlled trial. Surg Endosc 31:127–134CrossRefPubMed
32.
Zurück zum Zitat Smith SR, Draganic B, Pockney P, Holz P, Holmes R, Mcmanus B, Carroll R (2015) Transversus abdominis plane blockade in laparoscopic colorectal surgery: a double-blind randomized clinical trial. Int J Colorectal Dis 30:1237–1245CrossRefPubMed Smith SR, Draganic B, Pockney P, Holz P, Holmes R, Mcmanus B, Carroll R (2015) Transversus abdominis plane blockade in laparoscopic colorectal surgery: a double-blind randomized clinical trial. Int J Colorectal Dis 30:1237–1245CrossRefPubMed
Metadaten
Titel
Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program
verfasst von
Basilio Pirrera
Vincenzo Alagna
Andrea Lucchi
Pierluigi Berti
Carlo Gabbianelli
Giacomo Martorelli
Lorella Mozzoni
Federico Ruggeri
Alessandro Ingardia
Giuseppe Nardi
Gianluca Garulli
Publikationsdatum
01.07.2017
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 1/2018
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-5686-7

Weitere Artikel der Ausgabe 1/2018

Surgical Endoscopy 1/2018 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.