Competing interests
The authors declare the following conflicts of interest: TY has received honoraria from Eisai Co., Ltd., outside the submitted work. NM has received honoraria and research funding from Chugai, AstraZeneca, Pfizer, Eli Lily, and Eisai Co., Ltd., honoraria from Takeda, and research funding from Kyowa Hakko Kirin, MSD, Novartis, and Daiichi Sankyo outside the submitted work, and has served as a board member of JBCRG. SS has received grants and honoraria from Eisai Co., Ltd., Chugai, and AstraZeneca, Takeda, Novartis, and Taiho, honoraria from Kyowa Hakko Kirin, Pfizer, Daiichi Sankyo, and Nihon Kayaku, and grants from Ono outside the submitted work, and has served as a board member of JBCRG. YI has received funding from Chugai and Eisai Co., Ltd., and grants from Daiichi Sankyo, Novartis, Parexel, EPS, MSD, AstraZeneca, Eli Lilly, Kyowa Hakko Kirin, Covance, Taiho, and A2 Healthcare outside the submitted work. TT has received honoraria and research funding from Daiichi Sankyo, Kyowa Hakko Kirin, and Eisai Co., Ltd., honoraria from Pfizer and Eli Lilly, and research funding from Ono, MSD, Merck Serono, Taiho, Novartis, and Chugai outside the submitted work. MT has received lecture fees from Eisai Co., Ltd., Chugai, AstraZeneca, Pfizer, Taiho, Kyowa Hakko Kirin, and Eli Lilly outside the submitted work. HH is an employee of Eisai Co., Ltd. SM has received honoraria from Chugai and Eisai Co., Ltd., AstraZeneca, Pfizer, and Taiho outside the submitted work. SO has received honoraria and research funding from Chugai, Eisai Co., Ltd., and Daiichi Sankyo, research funding from Taiho, and honoraria from AstraZeneca, Novartis, and Kyowa Hakko Kirin outside the submitted work, and has served as a board member of JBCRG. YK has received research funds and honoraria for lectures from Chugai, Kyowa Hakko Kirin, and Eisai Co., Ltd. outside the submitted work. YS has received honoraria for lectures and an article from Eisai Co., Ltd. outside the submitted work. KA, JT, T Iwatani, KK, MK, HT, T Iwasa, and TK have no conflicts of interest to declare.