Skip to main content
main-content

01.12.2014 | Research article | Ausgabe 1/2014 Open Access

The Journal of Headache and Pain 1/2014

Treatment adherence among new triptan users: a 2-year cohort study in Taiwan

Zeitschrift:
The Journal of Headache and Pain > Ausgabe 1/2014
Autoren:
Ting-Bin Chen, Yung-Tai Chen, Jong-Ling Fuh, Chao-Hsiun Tang, Shuu-Jiun Wang
Wichtige Hinweise
Ting-Bin Chen, Yung-Tai Chen contributed equally to this work.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

SJW conceptualized and designed the study, analyzed the data, and wrote the manuscript. TBC conceptualized and designed the study, and wrote the manuscript. YTC conceptualized, analyzed the data, and wrote the manuscript. JLF conceptualized, designed the study, and wrote the manuscript. CHT conceptualized, designed the study and analyzed the data. All authors read and approved the final manuscript.

Abstract

Background

The persistence of triptan use among newly prescribed users is low in the United States and European countries. However, triptan refill patterns in Asian primary care practices have not been well described.

Methods

Data from the National Health Insurance Research Database in Taiwan were used to conduct a retrospective cohort analysis from 2005 to 2008. All participants were followed for 2 years after receiving a new triptan prescription. Refill and 2-year retention rates of newly prescribed triptans were calculated, and predictors of the first triptan refill and 2-year retention were analyzed.

Results

Of the 13,951 participants with a new triptan prescription (99.9% sumatriptan), 67.4% were prescribed by a neurologist, 67.4% were prescribed at least one prophylactic agent for migraine. Of them, 34.3% adhered to the newly prescribed triptan at the first refill, 0.01% switched to another triptan, and 40.9% switched to a non-triptan acute migraine medication. The 2-year retention rate was 4.0%. The frequency of headache-related neurologic visits for 1 year before the index date, first prescription of triptan or other acute medications, first triptan prescription by a neurologist, and prophylactic use were associated with higher first refill rates. The frequency of headache-related neurologic visits 1 year before the index date and first triptan prescription by a neurologist were related to higher 2-year retention rates. Diabetes mellitus and first triptan prescription at a local medical clinic were associated with reduced probability of continued triptan use at the first refill and 2 years.

Conclusions

Similar to Western societies, the refill and 2-year retention rates were low in new users of triptans. Frequency of neurologic visits and triptan prescription by a neurologist were significant predictors of adherence.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2014

The Journal of Headache and Pain 1/2014 Zur Ausgabe

Neu im Fachgebiet AINS

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update AINS und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise