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22.02.2018 | Co-infections and Comorbidity (S Naggie, Section Editor) | Ausgabe 2/2018

Current HIV/AIDS Reports 2/2018

Treatment of Hepatitis C during Pregnancy-Weighing the Risks and Benefits in Contrast to HIV

Zeitschrift:
Current HIV/AIDS Reports > Ausgabe 2/2018
Autoren:
A. Sidney Barritt IV, Ravi Jhaveri
Wichtige Hinweise
This article is part of the Topical Collection on Co-infections and Comorbidity

Abstract

Purpose of Review

Increasing hepatitis C virus (HCV) cases over the past decade have raised concerns about subsequent increased cases in infants due to mother to child transmission (MTCT). Many are reminded of the early days of HIV and the rationale for using antiretroviral agents during pregnancy.

Recent Findings

Direct-acting antivirals (DAAs) that are highly potent, all-oral, short-duration regimens that cure HCV have led many to consider what it would entail to use DAAs for pregnant women. Considering HIV and Hepatitis B virus (HBV) as two infections with MTCT to draw lessons from, DAA use to interrupt HCV MTCT comes with risks, costs, and many potential benefits.

Summary

When considering how to effectively curb the current epidemic of HCV in the US population, using DAAs to treat pregnant women with HCV offers potential benefits to the mother immediately, to the pair in the short-term and to the child, family, and society over a lifetime.

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