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Medical Oncology

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01.01.2017 | Original Paper

Treatment of lung tumours with high-energy microwave ablation: a single-centre experience

verfasst von: Anna Maria Ierardi, Andrea Coppola, Natalie Lucchina, Gianpaolo Carrafiello

Erschienen in: Medical Oncology | Ausgabe 1/2017

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Abstract

The purpose of our study is to report safety, technical success, effectiveness, local progression-free survival (LPFS) and overall survival of percutaneous microwave ablation (MWA) to treat lung tumours unsuitable for surgery. Nineteen patients with thirty-one tumours (mean diameter 2.4 cm) underwent percutaneous MWA in 28 sessions. Microwave ablation was carried out using a 2450-MHz generator (Emprint/Covidien, Boulder, CO, USA). Procedures were performed under cone-beam CT (CBCT) and under fluoro-CT (one session) guidance. Safety, technical success, effectiveness, LPFS and overall survival (OS) were evaluated. Safety was defined as the frequency of major and minor complications. The efficacy was evaluated on the basis of imaging characteristics, using RECIST criteria. CT follow-up was performed at 1, 3 and 6 months and yearly. LPFS was defined as the interval between MWA treatment and evidence of local recurrence, if there was any. OS was defined as the percentage of patients who were still alive. We registered one major complication (purulent hydro-pneumothorax). Minor complications were spontaneously resolved (pneumothorax and perilesional haemorrhagic effusion). Technical success was 100%. Residual disease was registered in two cases, one of whom was retreated. Complete ablation was obtained in the remaining cases (90.3%). During available follow-up (mean 9.6 months), 9/31 tumours demonstrated local recurrence. Five tumours were retreated, and none of them presented residual disease during follow-up (LPFS 22.6%). Overall survival was 93.8%. Percutaneous high-energy MWA is a safe, effective and confident technique to treat lung tumours not suitable for surgery.

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Titel: Treatment of lung tumours with high-energy microwave ablation: a single-centre experience
verfasst von: Anna Maria Ierardi
Andrea Coppola
Natalie Lucchina
Gianpaolo Carrafiello
Publikationsdatum: 01.01.2017
Verlag: Springer US
Erschienen in: Medical Oncology / Ausgabe 1/2017
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI: https://doi.org/10.1007/s12032-016-0861-6

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24.04.2024 | DGIM 2024 | Nachrichten

Springer Medizin

Treatment of lung tumours with high-energy microwave ablation: a single-centre experience

Abstract

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Springer Medizin

Abstract

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