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Erschienen in:

04.09.2024 | Research

Trends in human papillomavirus infection and genotype distribution among males in Chongqing, China (2017–2022): an observational study

verfasst von: Xiyang Yi, Hongjiao Chen, Guangjie Wu, Yanqi Hu, Xiaojun Tang

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 11/2024

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Abstract

Purpose

This study aimed to investigate Human papillomavirus (HPV) infection and genotyping in men from Chongqing and analyze age-related trends to provide insights for HPV prevention and vaccination plans tailored for men in Chongqing, China.

Methods

This study is an observational study. We investigated male patients who underwent HPV screening at two hospitals in Chongqing from 2017 to 2022, totaling 4,381 cases, aged 18 to 85. HPV genotyping was conducted using the Hybribio Rapid GenoArray kit.

Results

Among the 4,381 men, the overall HPV prevalence was 14.9%, peaking at 19.3% in 2022. Single HPV infection was 11.5%, and multiple infection was 3.4%. The most prevalent genotypes were HPV-52, HPV-16, and HPV-58. Single high-risk HPV infection peaked in the 36–45 age group, while multiple high-risk HPV infection decreased with age (P-trend < 0.01). Prevalence in the ≤ 25 age group was 3.7%. Single low-risk HPV infection also decreased with age (P-trend = 0.03). Genotypes covered by the nonavalent vaccine had the highest prevalence, increasing with age. Co-infection of HPV-16 with HPV-52 and HPV-58 was common. Single HPV infections were prevalent in cases of urethritis (30.8%), anogenital warts (36.4%), and genital warts (26.3%), while multiple HPV infections were significant in anogenital warts (18.2%).

Conclusions

Single HPV infection was predominant in Chongqing, with HPV-52, HPV-16, HPV-58, HPV-53, and HPV-39 being the most prevalent genotypes. The prevalence of genotypes covered by the nonavalent vaccine increased with age. This study offers valuable insights for developing male-specific HPV prevention strategies in Chongqing.
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Metadaten
Titel
Trends in human papillomavirus infection and genotype distribution among males in Chongqing, China (2017–2022): an observational study
verfasst von
Xiyang Yi
Hongjiao Chen
Guangjie Wu
Yanqi Hu
Xiaojun Tang
Publikationsdatum
04.09.2024
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 11/2024
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-024-04933-5

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