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01.12.2015 | Research article | Ausgabe 1/2015 Open Access

BMC Public Health 1/2015

Trends in silicosis prevalence and the healthy worker effect among gold miners in South Africa: a prevalence study with follow up of employment status

Zeitschrift:
BMC Public Health > Ausgabe 1/2015
Autoren:
David Knight, Rodney Ehrlich, Katherine Fielding, Hannah Jeffery, Alison Grant, Gavin Churchyard
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12889-015-2566-8) contains supplementary material, which is available to authorized users.

Competing interests

Prof R. Ehrlich has prepared expert reports for lawyers acting in silicosis litigation matters.

Authors’ contributions

DK, RE, KF and GC participated in conception of the silicosis study, analysis, literature review and manuscript preparation. AG and HJ participated in analysis and manuscript preparation. All have read and approved the final manuscript.

Abstract

Background

Given the intimate association between silicosis and tuberculosis, understanding the epidemiology of the South African gold mining industry silicosis epidemic is essential to current initiatives to control both silicosis and tuberculosis in this population, one of the most heavily affected globally. The study’s objectives were to compare the prevalence of silicosis among working black gold miners in South Africa during 2004–2009 to that of previous studies, including autopsy series, and to analyse the influence of silicosis and/or tuberculosis on exiting employment.

Methods

Routine chest radiographs from a cohort of gold miners were read for silicosis by an experienced reader (I), and a subset re-read by a B-trained reader (II). Two methods of presenting the readings were used. Additionally, with baseline status of silicosis and previous or active tuberculosis as predictors, survival analysis examined the probability of exiting the workforce for any reason during 2006–2011.

Results

Reader I read 11 557 chest radiographs and reader II re-read 841. Overall, silicosis prevalence (ILO ≥1/0: 5.7 and 6.2 % depending on reader method) was similar to the age adjusted prevalence found in a large study in 1984 (5.0 %). When comparison was restricted to a single mine shaft previously studied in 2000, a decline in prevalence (ILO ≥1/1) was suggested for one of the reading methods (duration adjusted 20.5 % vs. 13.0 % in the current study). These findings are discordant with a long-term rising autopsy prevalence of silicosis over this period. Overall, relative to miners with neither disease, the adjusted hazard ratio for exiting employment during the follow-up period was 1.54 for baseline silicosis [95 % confidence interval (CI) 1.17, 2.04], 1.71 for tuberculosis (95 % CI 1.51, 1.94) and 1.53 for combined disease (95 % CI 1.20, 1.96).

Conclusions

This study found, a) there was no significant decline in overall silicosis prevalence among working black miners in the South African gold mining industry between 1984 and 2004–2009, and b) a possible decline at one mine shaft more recently. In the absence of evidence of declining respirable silica concentrations between the 1980s and 2000s, the trends found are plausibly due to a healthy worker survivor effect, which may be accelerating.
Zusatzmaterial
Additional file 1: Table S1. Inter-reader agreement on silicosis. a: Inter-reader agreement on silicosis: reader I versus reader II. b: Inter-reader agreement on silicosis: reader I vs. reader II, stratified by whether reader I read signs of tuberculosis as present or absent. (DOCX 18 kb)
12889_2015_2566_MOESM1_ESM.docx
Literatur
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