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Journal of Natural Medicines

Erschienen in:

01.09.2018 | Note

Two new oleanane derivatives from the fruits of Leonurus japonicus and their cytotoxic activities

verfasst von: Wenwen Peng, Guanghu Huo, Lixia Zheng, Zhonghua Xiong, Xugen Shi, Dayong Peng

Erschienen in: Journal of Natural Medicines | Ausgabe 1/2019

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Abstract

Two new oleanane derivatives, leonuronins A and B (1 and 2), along with three known oleanane triterpenes (3–5) were isolated from the fruits of Leonurus japonicus. Their structures were elucidated on the basis of NMR, MS, IR and UV spectroscopic data. The new compounds were tested for cytotoxic activities against A549 and Hela cancer cell lines. Compounds 1 and 2 exhibited weak cytotoxicity with IC₅₀ values ranging from 6.97 to 18.13 μM.

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Titel: Two new oleanane derivatives from the fruits of Leonurus japonicus and their cytotoxic activities
verfasst von: Wenwen Peng
Guanghu Huo
Lixia Zheng
Zhonghua Xiong
Xugen Shi
Dayong Peng
Publikationsdatum: 01.09.2018
Verlag: Springer Singapore
Erschienen in: Journal of Natural Medicines / Ausgabe 1/2019
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-018-1244-4

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Two new oleanane derivatives from the fruits of Leonurus japonicus and their cytotoxic activities

Abstract

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

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