Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Typ-2-Diabetes und Adipositas Klimawandel und Gesundheit Neues aus dem Markt Praxis und Beruf Seltene Erkrankungen GOÄ & EBM
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Fachpsychotherapie Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende Patientenratgeber
Erweiterte Suche
Anmelden
nach oben
Journal of Natural Medicines
Erschienen in:

29.11.2024 | Note

Two novel butyrolactone lignan dimers from leaves of Castanopsis chinensis and their anti-inflammatory activities

verfasst von: Ya-Feng Wang, Ping Lin, Nao Pang, Zhang-Bin Liu, Bing-Yuan Yang, Rui-Jie He, Yong-Lin Huang

Erschienen in: Journal of Natural Medicines | Ausgabe 1/2025

Einloggen, um Zugang zu erhalten

Abstract

Castanopsis genus (Fagaceae) were rich in plant polyphenols and often used as medicinal plants. In this study, two new lignan dimer compounds with anti-inflammatory activity and four known compounds were isolated and identified from 80% methanolic extract of Castanopsis chinensis leaves. The structure determination supported by computational chemistry and extensive spectroscopic analysis. Two new lignan dimer compounds significantly inhibited LPS-induced NO production in RAW 264.7 cells at 10 µM without cytotoxicity.

Graphical abstract

Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
CAS (1998) Flora Republicae Popularis Sinicae. China Science Publishing & Media Ltd., Press Inc, Beijing
2.
Huang YL, Wang YF, Liu JL, Wang L, Tanaka T, Chen YY, Lu FL, Li DP (2017) Phenolic compounds from the leaves of Castanopsis fargesii. Molecules 22:162–162CrossRefPubMedPubMedCentral
3.
Wang YF, He RJ, Li DP, Huang YL (2018) Phytochemical and chemotaxonomic study on Castanopsis fargesii Franch. Biochem Syst Ecol 78:113–115CrossRef
4.
Yang BY, Pang N, He RJ, Wang YF, Huang YL (2022) Triterpene hexahydroxydiphenoyl ester and phenol glucosides from the leaves of Castanopsis eyrie (Champ. ex Benth.) Hutch. Nat Prod Res 38:1–7
5.
Chen HF, Tanaka T, Nonaka GI, Fujioka T, Mihashi K (1993) Phenylpropanoid-substituted catechins from Castanopsis hystrix and structure revision of cinchonains. Phytochemistry 33:183–187CrossRef
6.
Lin P, Wang YF, He RJ, Yang BY, Liu ZB, Li M, Huang YL (2022) A new phenol glucoside from leaves of Castanopsis chinensis. Chin Herbal Med 53:5271–5275
7.
Mou XF, Bian WT, Liu M, Wang Y, Yang RY, Wang CY, Shao CL (2014) Study on butyrolatones isolated from a sea hare-derived fungus Aspergillus terreus and their biological activities. Chin J Mar Drugs 33:16–22
8.
Ren YL, Yang JS (2002) The Spectoscopic fratures of dibenzylbutyrolactone lignans. J Spectrosc 19:15–24
9.
Li N, Wu JL, Sakai JI, Ando M (2003) Dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii. J Nat Prod 66:1421–1426CrossRefPubMed
10.
Harmatha J, Budĕšínskў M, Trka A (1982) Components of Senecio pancicii DEGEN var. arnautorum (VELEN.) STOJ., STEF. et KIT. and S. Pancicii DEGEN var. Pancicii. Collect Czech Chem Commun 47:644–663CrossRef
11.
Miyamae Y, Kurisu M, Han J, Isoda H, Shigemori H (2011) Structure-activity relationship of caffeoylquinic acids on the accelerating activity on ATP production. Chem Pharm Bull 59:502–507CrossRef
12.
Jin Y, Sun Y, Wu YN, Zhang CY (2017) Chemical constituents from Stem Barks of Pandanus tectorius. Chin Pharm J 52:1223–1226
13.
Lee EJ, Kim JS, Kim HP, Lee JH, Kang SS (2010) Phenolic constituents from the flower buds of Lonicera japonica and their 5-lipoxygenase inhibitory activities. Food Chem 120:134–139CrossRef
14.
Romussi G, Bignardi G, Pizza C (1988) Constituents of cupuliferae, XII. Minor acylated flavonoids from Quercus cerris L. Liebigs Ann Chem 10:989–991CrossRef
15.
Frank N (2012) The ORCA program system. Wires Comput Mol Sci 2:73–78CrossRef
16.
Stephens PJ, Harada N (2010) ECD cotton effect approximated by the Gaussian curve and other methods. Chirality 22:229–233CrossRefPubMed
17.
Wang SH, Ji L, Zhang DX, Guo HY, Wang YS, Li W (2022) Synthesis and anti-inflammatory activity of 1-methylhydantoin cinnamoyl imides. Molecules 27:8481–8481CrossRefPubMedPubMedCentral
18.
Liu YX, Song HJ, Xu JX, Bi GM, Meng DL (2022) Anti-inflammatory abietanes diterpenes and triterpenoids isolated from Clinopodium polycephalum. Fitoterapia 161:105244CrossRefPubMed
Metadaten
Titel
Two novel butyrolactone lignan dimers from leaves of Castanopsis chinensis and their anti-inflammatory activities
verfasst von
Ya-Feng Wang
Ping Lin
Nao Pang
Zhang-Bin Liu
Bing-Yuan Yang
Rui-Jie He
Yong-Lin Huang
Publikationsdatum
29.11.2024
Verlag
Springer Nature Singapore
Erschienen in
Journal of Natural Medicines / Ausgabe 1/2025
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI
https://doi.org/10.1007/s11418-024-01864-5

Weitere Artikel der Ausgabe 1/2025

Azamollugin, a mollugin derivative, has inhibitory activity on MyD88- and TRIF-dependent pathways

  • Original Paper

Isolation of new indole alkaloid triglucoside from the aqueous extract of Uncaria rhynchophylla

  • Open Access
  • Original Paper

High-resolution X-ray computed tomography for identifying herbal medicines was as effective as microscopic examination

  • Natural Resource Letter

Inhibition of amyloid β aggregation and BACE1, and protective effect on SH-SY5Y cells, by p-terphenyl compounds from mushroom Thelephora aurantiotincta

  • Note

Research on the quality evaluation of crude drugs

  • Open Access
  • Review

Chemical profile and biological activities of Lysiphyllum binatum (Blanco) de Wit

  • Original Paper