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Erschienen in: Die Diabetologie 2/2023

01.03.2023 | Typ-2-Diabetes | Leitthema

Präzisionstherapie bei Diabetes mellitus Typ 2

verfasst von: Juergen Graessler, Stefan R. Bornstein, Prof. Dr. med. Nikolaos Perakakis

Erschienen in: Die Diabetologie | Ausgabe 2/2023

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Zusammenfassung

Die sog. Präzisionstherapie ist ein neues medizinisches Konzept, das, unter Berücksichtigung aller individuellen Besonderheiten, die Entwicklung von personalisierten Präventions- oder Behandlungsstrategien zum Ziel hat. Zunächst werden Möglichkeiten der Präzisionsprävention von HochrisikopatientInnen für Diabetes mellitus Typ 2 (T2DM) inklusive individualisierter Lebensstilinterventionen, Präzisionsernährung und früher pharmakologischer Interventionen diskutiert. Darauf aufbauend werden aktuelle Ansätze zur Entwicklung von Präzisionstherapiestrategien aufgezeigt, die aus der Gesamtheit aller verfügbaren genetischen, biochemischen und klinischen Informationen eines Individuums abgeleitet werden. Ziel der Präzisionstherapie ist das Erreichen eines maximalen Therapieerfolgs bei minimalen Nebenwirkungen im medizinischen Alltag. Aufgrund der Verfügbarkeit neuer Medikamentengruppen und verbesserter analytischer Möglichkeiten erfordert die Herausarbeitung von Präzisionstherapien eine ständige Weiterentwicklung.
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Metadaten
Titel
Präzisionstherapie bei Diabetes mellitus Typ 2
verfasst von
Juergen Graessler
Stefan R. Bornstein
Prof. Dr. med. Nikolaos Perakakis
Publikationsdatum
01.03.2023
Verlag
Springer Medizin
Erschienen in
Die Diabetologie / Ausgabe 2/2023
Print ISSN: 2731-7447
Elektronische ISSN: 2731-7455
DOI
https://doi.org/10.1007/s11428-023-01013-8

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