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Erschienen in: European Radiology 6/2017

21.09.2016 | Neuro

Ultra-high-resolution C-arm flat-detector CT angiography evaluation reveals 3-fold higher association rate for sporadic intracranial cavernous malformations and developmental venous anomalies: a retrospective study in consecutive 58 patients with 60 cavernous malformations

verfasst von: Burak Kocak, Osman Kizilkilic, Buge Oz, Dogu Vuralli Bakkaloglu, Cihan Isler, Naci Kocer, Civan Islak

Erschienen in: European Radiology | Ausgabe 6/2017

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Abstract

Objectives

The imaging and surgical literature has confusing association rates for the association between sporadic intracranial cavernous malformations (CMs) and developmental venous anomalies (DVAs). In this study, our purpose was to determine the association rate using ultra-high-resolution C-arm flat-detector CT angiography (FDCTA) and compare it with literature.

Methods

Fifty-eight patients with 60 sporadic intracranial CMs that underwent an FDCTA study were included in our retrospective study. Re-evaluation of radiological data was performed based on the criteria defined by authors. Isotropic volumetric reconstructions with ultra-high resolution (voxel size of 102 μm3 for initial; 67 μm3 and 32 μm3 for further evaluation) were used for assessment. Sixteen patients underwent surgery for excision of their CMs.

Results

Fifty-one of all patients (87.9 %) were associated with a DVA. Undefined local venous structures (UD-LVSs) were observed in the remaining 7 patients (12.1 %). The strength of interobserver agreement was excellent [kappa(k) coefficient = 0.923].

Conclusions

Ultra-high-resolution FDCTA evaluation of CMs and DVAs reveals 3-fold higher association rate compared to the literature. FDCTA for patients with sporadic CMs could help identify the associated DVAs that remained undetected or unclear with other imaging modalities, which can be useful in decision-making processes, planning surgery, and during operation.

Key Points

FDCTA evaluation reveals the highest (3-fold) association rate in literature
FDCTA helps detect and define DVAs that remained unclear with other modalities
Ratio of DVAs/UD-LVSs (“variants” in MRI) increases dramatically with FDCTA
FDCTA reveals venous angioarchitecture of CMs in high anatomical detail
FDCTA can be useful in decision-making, planning surgery, and during operation
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Metadaten
Titel
Ultra-high-resolution C-arm flat-detector CT angiography evaluation reveals 3-fold higher association rate for sporadic intracranial cavernous malformations and developmental venous anomalies: a retrospective study in consecutive 58 patients with 60 cavernous malformations
verfasst von
Burak Kocak
Osman Kizilkilic
Buge Oz
Dogu Vuralli Bakkaloglu
Cihan Isler
Naci Kocer
Civan Islak
Publikationsdatum
21.09.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 6/2017
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4595-9

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