Skip to main content
Erschienen in: Surgery Today 8/2016

18.11.2015 | Original Article

Ultrasound-guided ilioinguinal/iliohypogastric block did not reduce emergence delirium after ambulatory pediatric inguinal hernia repair: a prospective randomized double-blind study

verfasst von: Nobuko Ohashi, Sadahei Denda, Kenta Furutani, Takayuki Yoshida, Yoshinori Kamiya, Reiko Komura, Hironobu Nishimaki, Yasushi Iinuma, Yutaka Hirayama, Shinichi Naitou, Koju Nitta, Hiroshi Baba

Erschienen in: Surgery Today | Ausgabe 8/2016

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Emergence delirium (ED) is a common postoperative complication of ambulatory pediatric surgery done under general anesthesia with sevoflurane. However, perioperative analgesic techniques have been shown to reduce sevoflurane-induced ED. The primary objective of this investigation was to examine whether an ultrasound-guided ilioinguinal/iliohypogastric (II/IH) nerve block for ambulatory pediatric inguinal hernia repair could reduce the incidence of sevoflurane-induced ED.

Methods

The subjects of this prospective randomized double-blind study were 40 boys ranging in age from 1 to 6 years, who were scheduled to undergo ambulatory inguinal hernia repair. The patients were randomized to either receive or not to receive an ultrasound-guided II/IH nerve block (Group B and Group NB, respectively). General anesthesia was maintained with sevoflurane and nitrous oxide. The primary outcome assessed was ED, evaluated using the Pediatric Anesthesia Emergence Delirium (PAED) scale 30 min after emergence from general anesthesia. The secondary outcomes assessed were postoperative pain, evaluated using the Behavioral Observational Pain Scale (BOPS), and the amount of intra-operative sevoflurane given.

Results

The median PAED scale scores did not differ between Groups B and NB at 30 min (P = 0.41). BOPS scores also did not differ significantly between the groups, but the mean amount of intraoperative sevoflurane given was significantly lower in Group B than in Group NB (P < 0.01).

Conclusions

Ultrasound-guided II/IH nerve block for ambulatory pediatric inguinal hernia repair did not reduce ED, but it did decrease the amount of intra-operative sevoflurane needed.
Clinical Trial Registration: UMIN000008586.
Literatur
2.
Zurück zum Zitat Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients. Anesth Analg. 1996;83:917–20.PubMed Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients. Anesth Analg. 1996;83:917–20.PubMed
3.
Zurück zum Zitat Ibacache ME, Muñoz HR, Brandes V, Morales AL. Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children. Anesth Analg. 2004;98:60–3.CrossRefPubMed Ibacache ME, Muñoz HR, Brandes V, Morales AL. Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children. Anesth Analg. 2004;98:60–3.CrossRefPubMed
4.
Zurück zum Zitat Aouad MT, Yazbeck-Karam VG, Nasr VG, El-Khatib MF, Kanazi GE, Bleik JH. A single dose of propofol at the end of surgery for the prevention of emergence agitation in children undergoing strabismus surgery during sevoflurane anesthesia. Anesthesiology. 2007;107:733–8.CrossRefPubMed Aouad MT, Yazbeck-Karam VG, Nasr VG, El-Khatib MF, Kanazi GE, Bleik JH. A single dose of propofol at the end of surgery for the prevention of emergence agitation in children undergoing strabismus surgery during sevoflurane anesthesia. Anesthesiology. 2007;107:733–8.CrossRefPubMed
5.
Zurück zum Zitat Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. The effect of fentanyl on the emergence characteristics after desflurane or sevoflurane anesthesia in children. Anesth Analg. 2002;94:1178–81.CrossRefPubMed Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. The effect of fentanyl on the emergence characteristics after desflurane or sevoflurane anesthesia in children. Anesth Analg. 2002;94:1178–81.CrossRefPubMed
6.
Zurück zum Zitat Cohen IT, Hannallah RS, Hummer KA. The incidence of emergence agitation associated with desflurane anesthesia in children is reduced by fentanyl. Anesth Analg. 2001;93:88–91.CrossRefPubMed Cohen IT, Hannallah RS, Hummer KA. The incidence of emergence agitation associated with desflurane anesthesia in children is reduced by fentanyl. Anesth Analg. 2001;93:88–91.CrossRefPubMed
7.
Zurück zum Zitat Voepel-Lewis T, Malviya S, Tait AR. A prospective cohort study of emergence agitation in the pediatric postanesthesia care unit. Anesth Analg. 2003;96:1625–30.CrossRefPubMed Voepel-Lewis T, Malviya S, Tait AR. A prospective cohort study of emergence agitation in the pediatric postanesthesia care unit. Anesth Analg. 2003;96:1625–30.CrossRefPubMed
8.
Zurück zum Zitat Willschke H, Marhofer P, Bösenberg A, Johnston S, Wanzel O, Cox SG, et al. Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children. Br J Anaesth. 2005;95:226–30.CrossRefPubMed Willschke H, Marhofer P, Bösenberg A, Johnston S, Wanzel O, Cox SG, et al. Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children. Br J Anaesth. 2005;95:226–30.CrossRefPubMed
9.
Zurück zum Zitat Weintraud M, Marhofer P, Bösenberg A, Kapral S, Willschke H, Felfernig M, et al. Ilioinguinal/iliohypogastric blocks in children: where do we administer the local anesthetic without direct visualization? Anesth Analg. 2008;106:89–93.CrossRefPubMed Weintraud M, Marhofer P, Bösenberg A, Kapral S, Willschke H, Felfernig M, et al. Ilioinguinal/iliohypogastric blocks in children: where do we administer the local anesthetic without direct visualization? Anesth Analg. 2008;106:89–93.CrossRefPubMed
10.
Zurück zum Zitat Willschke H, Bösenberg A, Marhofer P, Johnston S, Kettner S, Eichenberger U, et al. Ultrasonographic-guided ilioinguinal/iliohypogastric nerve block in pediatric anesthesia: what is the optimal volume? Anesth Analg. 2006;102:1680–4.CrossRefPubMed Willschke H, Bösenberg A, Marhofer P, Johnston S, Kettner S, Eichenberger U, et al. Ultrasonographic-guided ilioinguinal/iliohypogastric nerve block in pediatric anesthesia: what is the optimal volume? Anesth Analg. 2006;102:1680–4.CrossRefPubMed
11.
Zurück zum Zitat Warren-Stomberg M, Brattwall M, Jakobsson JG. Non-opioid analgesics for pain management following ambulatory surgery: a review. Minerva Anestesiol. 2013;79:1077–87.PubMed Warren-Stomberg M, Brattwall M, Jakobsson JG. Non-opioid analgesics for pain management following ambulatory surgery: a review. Minerva Anestesiol. 2013;79:1077–87.PubMed
12.
Zurück zum Zitat Sikich N, Lerman J. Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale. Anesthesiology. 2004;100:1138–45.CrossRefPubMed Sikich N, Lerman J. Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale. Anesthesiology. 2004;100:1138–45.CrossRefPubMed
13.
Zurück zum Zitat Hesselgard K, Larsson S, Romner B, Strömblad LG, Reinstrup P. Validity and reliability of the Behavioural Observational Pain Scale for postoperative pain measurement in children 1–7 years of age. Pediatr Crit Care Med. 2007;8:102–8.CrossRefPubMed Hesselgard K, Larsson S, Romner B, Strömblad LG, Reinstrup P. Validity and reliability of the Behavioural Observational Pain Scale for postoperative pain measurement in children 1–7 years of age. Pediatr Crit Care Med. 2007;8:102–8.CrossRefPubMed
14.
Zurück zum Zitat Kim HS, Kim CS, Kim SD, Lee JR. Fascia iliaca compartment block reduces emergence agitation by providing effective analgesic properties in children. J Clin Anesth. 2011;23:119–23.CrossRefPubMed Kim HS, Kim CS, Kim SD, Lee JR. Fascia iliaca compartment block reduces emergence agitation by providing effective analgesic properties in children. J Clin Anesth. 2011;23:119–23.CrossRefPubMed
15.
Zurück zum Zitat Isik B, Arslan M, Tunga AD, Kurtipek O. Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery. Paediatr Anaesth. 2006;16:748–53.CrossRefPubMed Isik B, Arslan M, Tunga AD, Kurtipek O. Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery. Paediatr Anaesth. 2006;16:748–53.CrossRefPubMed
16.
Zurück zum Zitat Cravero JP, Beach M, Thyr B, Whalen K. The effect of small dose fentanyl on the emergence characteristics of pediatric patients after sevoflurane anesthesia without surgery. Anesth Analg. 2003;97:364–7.CrossRefPubMed Cravero JP, Beach M, Thyr B, Whalen K. The effect of small dose fentanyl on the emergence characteristics of pediatric patients after sevoflurane anesthesia without surgery. Anesth Analg. 2003;97:364–7.CrossRefPubMed
17.
18.
Zurück zum Zitat Cunha FQ, Poole S, Lorenzetti BB, Ferreira SH. The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol. 1992;107:660–4.CrossRefPubMedPubMedCentral Cunha FQ, Poole S, Lorenzetti BB, Ferreira SH. The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol. 1992;107:660–4.CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Gürleyik E, Gürleyik G, Cetinkaya F, Unalmiser S. The inflammatory response to open tension-free inguinal hernioplasty versus conventional repairs. Am J Surg. 1998;175:179–82.CrossRefPubMed Gürleyik E, Gürleyik G, Cetinkaya F, Unalmiser S. The inflammatory response to open tension-free inguinal hernioplasty versus conventional repairs. Am J Surg. 1998;175:179–82.CrossRefPubMed
20.
Zurück zum Zitat Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol. Paediatr Anaesth. 2003;13:63–7.CrossRefPubMed Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol. Paediatr Anaesth. 2003;13:63–7.CrossRefPubMed
21.
Zurück zum Zitat Shen X, Dong Y, Xu Z, Wang H, Miao C, Soriano SG, et al. Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology. 2013;118:502–15.CrossRefPubMedPubMedCentral Shen X, Dong Y, Xu Z, Wang H, Miao C, Soriano SG, et al. Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology. 2013;118:502–15.CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, Zorumski CF, et al. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci. 2003;23:876–82.PubMed Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, Zorumski CF, et al. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci. 2003;23:876–82.PubMed
23.
Zurück zum Zitat Birmingham PK, Tobin MJ, Fisher DM, Henthorn TK, Hall SC, Coté CJ. Initial and subsequent dosing of rectal acetaminophen in children: a 24-hour pharmacokinetic study of new dose recommendations. Anesthesiology. 2001;94:385–9.CrossRefPubMed Birmingham PK, Tobin MJ, Fisher DM, Henthorn TK, Hall SC, Coté CJ. Initial and subsequent dosing of rectal acetaminophen in children: a 24-hour pharmacokinetic study of new dose recommendations. Anesthesiology. 2001;94:385–9.CrossRefPubMed
24.
Zurück zum Zitat Schmidt A, Björkman S, Akeson J. Preoperative rectal diclofenac versus paracetamol for tonsillectomy: effects on pain and blood loss. Acta Anaesthesiol Scand. 2001;45:48–52.CrossRefPubMed Schmidt A, Björkman S, Akeson J. Preoperative rectal diclofenac versus paracetamol for tonsillectomy: effects on pain and blood loss. Acta Anaesthesiol Scand. 2001;45:48–52.CrossRefPubMed
25.
Zurück zum Zitat Gandhi R, Sunder R. Postoperative analgesic efficacy of single high dose and low dose rectal acetaminophen in pediatric ophthalmic surgery. J Anaesthesiol Clin Pharmacol. 2012;28:460–4.CrossRefPubMedPubMedCentral Gandhi R, Sunder R. Postoperative analgesic efficacy of single high dose and low dose rectal acetaminophen in pediatric ophthalmic surgery. J Anaesthesiol Clin Pharmacol. 2012;28:460–4.CrossRefPubMedPubMedCentral
Metadaten
Titel
Ultrasound-guided ilioinguinal/iliohypogastric block did not reduce emergence delirium after ambulatory pediatric inguinal hernia repair: a prospective randomized double-blind study
verfasst von
Nobuko Ohashi
Sadahei Denda
Kenta Furutani
Takayuki Yoshida
Yoshinori Kamiya
Reiko Komura
Hironobu Nishimaki
Yasushi Iinuma
Yutaka Hirayama
Shinichi Naitou
Koju Nitta
Hiroshi Baba
Publikationsdatum
18.11.2015
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 8/2016
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-015-1280-6

Weitere Artikel der Ausgabe 8/2016

Surgery Today 8/2016 Zur Ausgabe

Leitlinien kompakt für die Allgemeinmedizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Facharzt-Training Allgemeinmedizin

Die ideale Vorbereitung zur anstehenden Prüfung mit den ersten 24 von 100 klinischen Fallbeispielen verschiedener Themenfelder

Mehr erfahren

Update Allgemeinmedizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.