nach oben

Intensive Care Medicine

Erschienen in:

11.02.2016 | Understanding the Disease

Understanding the Haldane effect

verfasst von: Jean-Louis Teboul, Thomas Scheeren

Erschienen in: Intensive Care Medicine | Ausgabe 1/2017

Einloggen, um Zugang zu erhalten

Excerpt

Several studies have proposed using either the venous-to-arterial carbon dioxide (CO₂) content (CCO₂) or the venous-to-arterial CO₂ pressure (PCO₂) difference to assess systemic hypoperfusion or tissue hypoxia. However, these two variables sometimes differ at the highest levels of CCO₂ because of the complex relationship between CCO₂ and PCO₂ involving the Haldane effect. …

Christiansen J, Douglas CG, Haldane JS (1914) The absorption and dissociation of carbon dioxide by human blood. J Physiol 48:244–271CrossRefPubMedPubMedCentral

Zhang H, Vincent JL (1993) Arteriovenous differences in PCO2 and pH are good indicators of critical hypoperfusion. Am Rev Respir Dis 148:867–871CrossRefPubMed

Dres M, Monnet X, Teboul JL (2012) Hemodynamic management of cardiovascular failure by using PCO(2) venous-arterial difference. J Clin Monit Comput 26:367–374CrossRefPubMed

Bakker J, Vincent JL, Gris P, Leon M, Coffernils M, Kahn RJ (1992) Veno-arterial carbon dioxide gradient in human septic shock. Chest 101:509–515CrossRefPubMed

Mekontso-Dessap A, Castelain V, Anguel N, Bahloul M, Schauvliege F, Richard C, Teboul JL (2002) Combination of venoarterial PCO2 difference with arteriovenous O2 content difference to detect anaerobic metabolism in patients. Intensive Care Med 28:272–277CrossRefPubMed

Vallet B, Teboul JL, Cain S, Curtis S (2000) Venoarterial CO(2) difference during regional ischemic or hypoxic hypoxia. J Appl Physiol 89:1317–1321PubMed

Jakob SM, Groeneveld ABJ, Teboul JL (2015) Venous–arterial CO2 to arterial–venous O2 difference ratio as a resuscitation target in shock states? Intensive Care Med 41:936–938CrossRefPubMed

Giovannini I, Chiarla C, Boldrini G, Castagneto M (1993) Calculation of venoarterial CO2 concentration difference. J Appl Physiol 74:959–964PubMed

Mallat J, Benzidi Y, Salleron J, Lemyze M, Gasan G, Vangrunderbeeck N, Pepy F, Tronchon L, Vallet B, Thevenin D (2014) Time course of central venous-to-arterial carbon dioxide tension difference in septic shock patients receiving incremental doses of dobutamine. Intensive Care Med 40:404–411CrossRefPubMed

10.

Ospina-Tascón GA, Umaña M, Bermúdez WF, Bautista-Rincón DF, Valencia JD, Madriñán HJ, Hernandez G, Bruhn A, Arango-Dávila C, De Backer D (2016) Can venous-to-arterial carbon dioxide differences reflect microcirculatory alterations in patients with septic shock? Intensive Care Med 42:211–221CrossRefPubMed

11.

Ospina-Tascon GA, Bautista-Rincon DF, Umana M, Tafur JD, Gutierrez A, Garcia AF, Bermudez W, Granados M, Arango-Davila C, Hernandez G (2013) Persistently high venous-to-arterial carbon dioxide differences during early resuscitation are associated with poor outcomes in septic shock. Crit Care 17:R294CrossRefPubMedPubMedCentral

12.

Vallee F, Vallet B, Mathe O, Parraguette J, Mari A, Silva S, Samii K, Fourcade O, Genestal M (2008) Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? Intensive Care Med 34:2218–2225CrossRefPubMed

13.

Citerio G, Bakker J, Bassetti M, Benoit D, Cecconi M, Curtis JR, Doig GS, Herridge M, Jaber S, Joannidis M, Papazian L, Perner A, Peters MJ, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Timsit JF, Azoulay E (2015) Year in review in Intensive Care Medicine 2014: I. Cardiac dysfunction and cardiac arrest, ultrasound, neurocritical care, ICU-acquired weakness, nutrition, acute kidney injury, and miscellaneous. Intensive Care Med 41:179–191CrossRefPubMedCentral

14.

Vallet B, Pinsky MR, Cecconi M (2013) Resuscitation of patients with septic shock: please “mind the gap”! Intensive Care Med 39:1653–1655CrossRefPubMedPubMedCentral

15.

Monnet X, Julien F, Ait-Hamou N, Lequoy M, Gosset C, Jozwiak M, Persichini R, Anguel N, Richard C, Teboul JL (2013) Lactate and veno-arterial carbon dioxide difference/arterial-venous oxygen difference ratio, but not central venous oxygen saturation, predict increase in oxygen consumption in fluid responders. Crit Care Med 41:1412–1420CrossRefPubMed

Titel: Understanding the Haldane effect
verfasst von: Jean-Louis Teboul
Thomas Scheeren
Publikationsdatum: 11.02.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 1/2017
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-016-4261-3

Neu im Fachgebiet AINS

11.04.2024 | Rückenschmerzen | Nachrichten

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

hier abonnieren

Springer Medizin

Understanding the Haldane effect

Excerpt

Neu im Fachgebiet AINS

Diclofenac-Gel versus Ibuprofen bei akuten Rückenschmerzen

Chronische Schmerzen nach Op. oft mit neuropathischer Komponente

Wie toxische Männlichkeit der Gesundheit von Männern schadet

Neue NIV-Leitlinie mit Anleitung zur Beatmungseinstellung vorgestellt

Update AINS

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2017

Decrease of thoracopulmonary compliance with pressure assist controlled ventilation in ARDS patients under ECMO and transported to a referral centre

Hyperglycemia and outcomes of medical intensive care unit patients with and without a history of diabetes mellitus in a Chinese population

Ten reasons why ICU patients should be mobilized early

Accuracy of esophageal pressure to assess transpulmonary pressure during mechanical ventilation

Children under … not admitted

The optimal blood glucose target in critically ill patients: more questions than answers

Neu im Fachgebiet AINS

Diclofenac-Gel versus Ibuprofen bei akuten Rückenschmerzen

Chronische Schmerzen nach Op. oft mit neuropathischer Komponente

Wie toxische Männlichkeit der Gesundheit von Männern schadet

Neue NIV-Leitlinie mit Anleitung zur Beatmungseinstellung vorgestellt

Update AINS