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Erschienen in: Intensive Care Medicine 3/2005

01.03.2005 | Correspondence

Unexpected recovery from prolonged hypoglycemic coma: a protective role of metformin?

verfasst von: Jean-Daniel Lalau, Kamel Masmoudi

Erschienen in: Intensive Care Medicine | Ausgabe 3/2005

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Excerpt

Sir: Accumulation of the biguanide antihyperglycemic agent metformin has been linked to lactic acidosis, a complication associated with a high mortality rate in critical illness. However, there is mounting evidence that metformin accumulation has no adverse prognostic significance per se and may even be protective in severe pathologies [1]. Here the complete recovery of an elderly woman who presented with prolonged hypoglycemic coma after sulfonylurea intoxication and metformin accumulation provides a new argument for a possible beneficial effect. …
Literatur
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Zurück zum Zitat Wiernsperger NF (2000) Metformin: intrinsic vasculoprotective properties. Diabetes Technol Ther 2:259–272CrossRef Wiernsperger NF (2000) Metformin: intrinsic vasculoprotective properties. Diabetes Technol Ther 2:259–272CrossRef
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Metadaten
Titel
Unexpected recovery from prolonged hypoglycemic coma: a protective role of metformin?
verfasst von
Jean-Daniel Lalau
Kamel Masmoudi
Publikationsdatum
01.03.2005
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 3/2005
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-004-2540-x

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