Background
Methods
Study population
Measurements
Statistical analyses
Results
Characteristics of the study population
Characteristics | Number (%) |
---|---|
Age (years) | |
< 40 | 44 (13.3) |
40 ~ 49 | 129 (38.9) |
50 ~ 59 | 123 (37.0) |
≥ 60 | 36 (10.8) |
Menopausal status | |
Postmenopause | 127 (38.3) |
Time since diagnosis (years) | |
≤ 1 | 73 (22.0) |
> 1, ≤ 3 | 160 (48.2) |
> 3, ≤ 5 | 66 (19.9) |
> 5 | 33 (9.9) |
Family history of breast cancer | |
Yes | 27 (8.1) |
Operation method of breast | |
BCS | 225 (67.8) |
Mastectomy | 79 (23.8) |
(NA)SSM | 28 (8.4) |
Operation method of axilla | |
SLNB | 212 (63.9) |
ALND | 120 (36.1) |
TNM stage | |
0 | 13 (3.9) |
I | 129 (38.9) |
II | 148 (44.6) |
III & IV | 42 (12.6) |
Multiplicity | |
Yes | 62 (18.7) |
Estrogen receptor | |
Positive | 260 (78.3) |
Progesterone receptor | |
Positive | 240 (72.3) |
HER2 | |
Positive | 95 (28.6) |
Chemotherapy | |
Yes | 248 (74.7) |
Hormonal therapy | |
Yes | 236 (71.1) |
Radiation therapy | |
Yes | 262 (78.9) |
Target therapy | |
Yes | 72 (21.7) |
Co-morbidity | |
Yes | 79 (23.8) |
Adjuvant treatment | |
During | 141 (42.5) |
After | 144 (43.4) |
Othersa | 47 (14.1) |
Factor analysis of needs
Rank | Item | Score (Mean ± SD) | Domain |
---|---|---|---|
1 | Needed help in coping with fear of recurrence | 2.04 ± 1.09 | Information and education |
2 | Needed information about correct diet (food to eat, food to avoid) | 1.98 ± 1.11 | Information and education |
3 | Needed information about current status of my illness and its future courses | 1.84 ± 1.14 | Information and education |
4 | Needed information or education about things that I can do at home for my health | 1.82 ± 1.13 | Information and education |
5 | Needed information about tests and treatments | 1.80 ± 1.16 | Information and education |
6 | Needed information about symptoms require a hospital visit | 1.79 ± 1.12 | Information and education |
7 | Needed help with worries about treatment sequelae | 1.79 ± 1.13 | Information and education |
8 | Wished to be able to seek doctor in a quick and easy way when in need | 1.78 ± 1.20 | Healthcare staff |
9 | Needed information about financial support for medical expenses from government | 1.77 ± 1.18 | Information and education |
10 | Wished my doctor to be easy, specific, and honest in his/her explanation | 1.74 ± 1.22 | Healthcare staff |
Needs by clinicopathological characteristics
Variable | Healthcare staff | Information and education | Psychological problem | Physical symptom | Social support | Hospital service | Religious support | Total |
---|---|---|---|---|---|---|---|---|
Age (years) | ||||||||
< 40 | 1.29 ± 1.04a | 1.48 ± 1.00 | 1.21 ± 1.11a | 0.91 ± 0.93ab | 0.72 ± 0.74 | 1.32 ± 1.17a | 0.65 ± 1.00 | 1.06 ± 0.84 |
40 ~ 49 | 1.53 ± 0.99ab | 1.74 ± 0.95 | 1.39 ± 0.94a | 1.13 ± 0.86bc | 0.82 ± 0.72 | 1.62 ± 0.99b | 0.96 ± 1.13 | 1.26 ± 0.76 |
50 ~ 59 | 1.69 ± 0.97b | 1.78 ± 0.84 | 1.47 ± 0.96b | 1.28 ± 0.85c | 0.96 ± 0.79 | 1.66 ± 1.04b | 0.98 ± 1.16 | 1.37 ± 0.72 |
≥ 60 | 1.28 ± 0.94a | 1.53 ± 0.85 | 1.06 ± 0.81a | 0.80 ± 0.69a | 0.70 ± 0.69 | 1.17 ± 0.97a | 0.83 ± 1.13 | 1.04 ± 0.61 |
p-value | 0.042 | 0.170 | 0.096 | 0.008 | 0.155 | 0.030 | 0.361 | 0.030 |
Menopausal status | ||||||||
Premenopause | 1.53 ± 1.00 | 1.72 ± 0.93 | 1.35 ± 0.97 | 1.09 ± 0.86 | 0.80 ± 0.70 | 1.57 ± 1.03 | 0.90 ± 1.13 | 1.24 ± 0.75 |
Postmenopause | 1.54 ± 0.98 | 1.67 ± 0.87 | 1.37 ± 0.96 | 1.16 ± 0.87 | 0.93 ± 0.82 | 1.50 ± 1.05 | 0.94 ± 1.12 | 1.27 ± 0.75 |
p-value | 0.930 | 0.648 | 0.866 | 0.519 | 0.144 | 0.519 | 0.794 | 0.652 |
Time since diagnosis (years) | ||||||||
≤ 1 | 1.56 ± 1.02 | 1.85 ± 0.85 | 1.56 ± 0.97 | 1.28 ± 0.96 | 0.93 ± 0.83 | 1.63 ± 1.07 | 0.99 ± 1.19 | 1.35 ± 0.79 |
> 1, ≤ 3 | 1.52 ± 0.99 | 1.71 ± 0.90 | 1.35 ± 0.96 | 1.09 ± 0.85 | 0.86 ± 0.72 | 1.63 ± 1.00 | 0.97 ± 1.11 | 1.27 ± 0.75 |
> 3, ≤ 5 | 1.40 ± 0.95 | 1.54 ± 0.95 | 1.18 ± 0.94 | 0.99 ± 0.79 | 0.70 ± 0.71 | 1.39 ± 1.05 | 0.73 ± 1.07 | 1.09 ± 0.68 |
> 5 | 1.59 ± 0.97 | 1.53 ± 0.94 | 1.26 ± 0.97 | 1.13 ± 0.82 | 0.79 ± 0.74 | 1.22 ± 1.03 | 0.77 ± 1.07 | 1.22 ± 0.76 |
p-value | 0.782 | 0.172 | 0.143 | 0.252 | 0.324 | 0.121 | 0.418 | 0.235 |
Family history of breast cancer | ||||||||
No | 1.55 ± 0.98 | 1.72 ± 0.90 | 1.37 ± 0.97 | 1.13 ± 0.86 | 0.85 ± 0.75 | 1.59 ± 1.04 | 0.94 ± 1.13 | 1.27 ± 0.74 |
Yes | 1.27 ± 1.05 | 1.45 ± 0.94 | 1.24 ± 0.96 | 1.00 ± 0.93 | 0.77 ± 0.80 | 1.01 ± 0.97 | 0.58 ± 0.99 | 1.08 ± 0.83 |
p-value | 0.151 | 0.138 | 0.486 | 0.451 | 0.567 | 0.006 | 0.111 | 0.209 |
Operation method of breast | ||||||||
BCS | 1.49 ± 0.99 | 1.67 ± 0.89 | 1.30 ± 0.96 | 1.06 ± 0.86 | 0.81 ± 0.73 | 1.50 ± 1.03 | 0.84 ± 1.10 | 1.24 ± 0.76 |
Mastectomy | 1.58 ± 0.94 | 1.77 ± 0.90 | 1.49 ± 0.96 | 1.21 ± 0.86 | 0.92 ± 0.78 | 1.69 ± 1.03 | 1.14 ± 1.19 | 1.41 ± 0.73 |
(NA)SSM | 1.46 ± 1.05 | 1.55 ± 1.09 | 1.38 ± 1.00 | 1.25 ± 0.84 | 0.81 ± 0.71 | 1.43 ± 1.11 | 0.74 ± 1.01 | 1.23 ± 0.81 |
p-value | 0.752 | 0.579 | 0.344 | 0.296 | 0.556 | 0.325 | 0.111 | 0.253 |
Operation method of axilla | ||||||||
SLNB | 1.48 ± 1.03 | 1.65 ± 0.93 | 1.32 ± 0.98 | 1.08 ± 0.85 | 0.84 ± 0.78 | 1.49 ± 1.04 | 0.94 ± 1.14 | 1.26 ± 0.78 |
ALND | 1.57 ± 0.91 | 1.75 ± 0.85 | 1.41 ± 0.94 | 1.19 ± 0.88 | 0.84 ± 0.68 | 1.64 ± 1.02 | 0.85 ± 1.08 | 1.33 ± 0.72 |
p-value | 0.430 | 0.308 | 0.444 | 0.265 | 0.954 | 0.218 | 0.486 | 0.453 |
TNM stage | ||||||||
0 | 1.31 ± 0.90 | 1.36 ± 0.82 | 1.01 ± 0.97a | 0.96 ± 0.91 | 0.49 ± 0.53a | 1.08 ± 0.85a | 0.42 ± 0.67 | 0.93 ± 0.61 |
I | 1.44 ± 1.02 | 1.60 ± 0.97 | 1.21 ± 0.94ab | 0.95 ± 0.78 | 0.69 ± 0.67ab | 1.40 ± 1.01ab | 0.90 ± 1.13 | 1.14 ± 0.74 |
II | 1.60 ± 0.99 | 1.77 ± 0.83 | 1.44 ± 0.96ab | 1.22 ± 0.88 | 0.96 ± 0.77b | 1.64 ± 1.06b | 0.95 ± 1.14 | 1.32 ± 0.74 |
III & IV | 1.63 ± 0.94 | 1.82 ± 0.96 | 1.62 ± 0.97b | 1.31 ± 0.96 | 1.00 ± 0.85b | 1.79 ± 1.04b | 1.00 ± 1.15 | 1.42 ± 0.79 |
p-value | 0.438 | 0.187 | 0.030 | 0.025 | 0.004 | 0.036 | 0.435 | 0.034 |
Multiplicity | ||||||||
No | 1.46 ± 0.98 | 1.66 ± 0.89 | 1.31 ± 0.95 | 1.07 ± 0.84 | 0.81 ± 0.73 | 1.50 ± 1.04 | 0.84 ± 1.08 | 1.20 ± 0.73 |
Yes | 1.82 ± 0.97 | 1.86 ± 0.97 | 1.57 ± 1.01 | 1.33 ± 0.93 | 0.99 ± 0.82 | 1.74 ± 1.03 | 1.25 ± 1.26 | 1.48 ± 0.80 |
p-value | 0.011 | 0.117 | 0.054 | 0.035 | 0.088 | 0.099 | 0.011 | 0.007 |
Estrogen receptor | ||||||||
Negative | 1.44 ± 0.96 | 1.63 ± 0.93 | 1.38 ± 0.99 | 1.16 ± 0.87 | 0.92 ± 0.80 | 1.47 ± 1.10 | 0.96 ± 1.16 | 1.25 ± 0.76 |
Positive | 1.56 ± 1.00 | 1.72 ± 0.90 | 1.35 ± 0.96 | 1.11 ± 0.86 | 0.83 ± 0.74 | 1.57 ± 1.02 | 0.92 ± 1.12 | 1.25 ± 0.75 |
p-value | 0.360 | 0.476 | 0.854 | 0.697 | 0.371 | 0.477 | 0.804 | 0.978 |
Progesterone receptor | ||||||||
Negative | 1.50 ± 0.94 | 1.71 ± 0.88 | 1.44 ± 0.95 | 1.22 ± 0.84 | 0.92 ± 0.78 | 1.52 ± 1.04 | 1.03 ± 1.18 | 1.31 ± 0.75 |
Positive | 1.55 ± 1.01 | 1.70 ± 0.92 | 1.33 ± 0.97 | 1.08 ± 0.87 | 0.83 ± 0.74 | 1.56 ± 1.04 | 0.88 ± 1.11 | 1.23 ± 0.75 |
p-value | 0.696 | 0.959 | 0.346 | 0.199 | 0.291 | 0.773 | 0.277 | 0.426 |
HER2 | ||||||||
Negative | 1.48 ± 0.99 | 1.64 ± 0.93 | 1.29 ± 0.96 | 1.07 ± 0.86 | 0.77 ± 0.70 | 1.46 ± 1.03 | 0.86 ± 1.14 | 1.19 ± 0.74 |
Positive | 1.63 ± 0.98 | 1.84 ± 0.83 | 1.52 ± 0.95 | 1.22 ± 0.86 | 1.01 ± 0.84 | 1.73 ± 1.05 | 1.03 ± 0.10 | 1.38 ± 0.74 |
p-value | 0.214 | 0.059 | 0.505 | 0.139 | 0.015 | 0.035 | 0.220 | 0.039 |
Chemotherapy | ||||||||
No | 1.49 ± 1.03 | 1.53 ± 0.91 | 1.26 ± 1.00 | 0.97 ± 0.81 | 0.75 ± 0.74 | 1.43 ± 1.02 | 1.05 ± 1.15 | 1.21 ± 0.76 |
Yes | 1.52 ± 0.97 | 1.74 ± 0.90 | 1.39 ± 0.95 | 1.16 ± 0.88 | 0.87 ± 0.74 | 1.58 ± 1.04 | 0.86 ± 1.10 | 1.31 ± 0.76 |
p-value | 0.821 | 0.071 | 0.298 | 0.099 | 0.238 | 0.283 | 0.183 | 0.349 |
Hormonal therapy | ||||||||
No | 1.53 ± 0.98 | 1.70 ± 0.92 | 1.40 ± 0.99 | 1.21 ± 0.92 | 0.90 ± 0.80 | 1.52 ± 1.12 | 0.85 ± 1.09 | 1.31 ± 0.78 |
Yes | 1.50 ± 0.99 | 1.69 ± 0.90 | 1.34 ± 0.95 | 1.07 ± 0.84 | 0.81 ± 0.72 | 1.55 ± 1.00 | 0.93 ± 1.13 | 1.28 ± 0.75 |
p-value | 0.801 | 0.938 | 0.624 | 0.201 | 0.320 | 0.858 | 0.585 | 0.753 |
Radiation therapy | ||||||||
No | 1.45 ± 0.93 | 1.69 ± 0.89 | 1.50 ± 0.92 | 1.16 ± 0.86 | 0.92 ± 0.78 | 1.52 ± 1.08 | 1.02 ± 1.15 | 1.32 ± 0.75 |
Yes | 1.52 ± 1.00 | 1.69 ± 0.91 | 1.31 ± 0.97 | 1.10 ± 0.86 | 0.81 ± 0.73 | 1.54 ± 1.02 | 0.87 ± 1.11 | 1.27 ± 0.76 |
p-value | 0.601 | 0.999 | 0.168 | 0.582 | 0.322 | 0.880 | 0.361 | 0.630 |
Target therapy | ||||||||
No | 1.48 ± 0.99 | 1.66 ± 0.92 | 1.30 ± 0.97 | 1.06 ± 0.86 | 0.78 ± 0.72 | 1.48 ± 1.03 | 0.87 ± 1.12 | 1.24 ± 0.75 |
Yes | 1.59 ± 0.99 | 1.81 ± 0.83 | 1.53 ± 0.91 | 1.29 ± 0.86 | 1.03 ± 0.81 | 1.77 ± 1.04 | 1.03 ± 1.12 | 1.44 ± 0.77 |
p-value | 0.462 | 0.189 | 0.085 | 0.056 | 0.016 | 0.050 | 0.312 | 0.063 |
Co-morbidity | ||||||||
No | 1.46 ± 0.94 | 1.78 ± 0.83 | 1.40 ± 0.94 | 1.19 ± 0.85 | 0.86 ± 0.73 | 1.52 ± 1.00 | 0.99 ± 1.17 | 1.28 ± 0.73 |
Yes | 1.52 ± 1.00 | 1.66 ± 0.93 | 1.34 ± 0.97 | 1.07 ± 0.86 | 0.82 ± 0.73 | 1.54 ± 1.04 | 0.91 ± 1.12 | 1.22 ± 0.75 |
p-value | 0.679 | 0.327 | 0.635 | 0.332 | 0.651 | 0.908 | 0.626 | 0.563 |
Adjuvant treatment | ||||||||
During | 1.50 ± 1.01 | 1.81 ± 0.88 | 1.43 ± 0.98ab | 1.21 ± 0.91ab | 0.94 ± 0.77b | 1.60 ± 1.08 | 0.99 ± 1.16 | 1.32 ± 0.77a |
After | 1.47 ± 0.96 | 1.58 ± 0.91 | 1.20 ± 0.91a | 0.98 ± 0.76a | 0.69 ± 0.67a | 1.46 ± 1.00 | 0.81 ± 1.09 | 1.13 ± 0.68ab |
Othersa | 1.77 ± 0.97 | 1.75 ± 0.97 | 1.67 ± 1.01b | 1.27 ± 0.98b | 1.01 ± 0.81b | 1.62 ± 1.04 | 1.06 ± 1.13 | 1.43 ± 0.83b |
p-value | 0.165 | 0.103 | 0.009 | 0.039 | 0.005 | 0.471 | 0.260 | 0.022 |
Needs by sociodemographic characteristics
Variable | n(%) | Healthcare staff | Information and education | Psychological problem | Physical symptom | Social support | Hospital service | Religious support | Total |
---|---|---|---|---|---|---|---|---|---|
Education | |||||||||
High school | 202 (63.3) | 1.51 ± 0.94 | 1.71 ± 0.87 | 1.39 ± 0.93 | 1.16 ± 0.86 | 0.88 ± 0.73 | 1.53 ± 1.00 | 0.85 ± 1.09 | 1.26 ± 0.72 |
College | 117 (36.7) | 1.51 ± 1.06 | 1.64 ± 0.97 | 1.03 ± 0.87 | 1.03 ± 0.87 | 0.77 ± 0.76 | 1.54 ± 1.09 | 0.98 ± 1.17 | 1.20 ± 0.78 |
p-value | 0.943 | 0.501 | 0.328 | 0.174 | 0.219 | 0.928 | 0.321 | 0.498 | |
Marital status | |||||||||
Single | 16(5.0) | 1.03 ± 1.12a | 1.19 ± 1.03a | 0.69 ± 0.94a | 0.93 ± 1.02 | 0.58 ± 0.87a | 1.00 ± 1.05a | 0.63 ± 1.02 | 0.84 ± 0.86a |
Married | 258 (81.4) | 1.49 ± 0.97ab | 1.67 ± 0.88b | 1.33 ± 0.94b | 1.10 ± 0.84 | 0.82 ± 0.72ab | 1.52 ± 1.02b | 0.91 ± 1.12 | 1.22 ± 0.72ab |
Separateda | 43 (13.6) | 1.75 ± 1.01b | 1.95 ± 0.94b | 1.66 ± 0.97b | 1.20 ± 0.91 | 1.00 ± 0.71b | 1.77 ± 1.03b | 1.03 ± 1.19 | 1.45 ± 0.78b |
p-value | 0.038 | 0.013 | 0.002 | 0.534 | 0.124 | 0.038 | 0.483 | 0.017 | |
Religion | |||||||||
Yes | 212 (66.9) | 1.47 ± 0.97 | 1.67 ± 0.92 | 1.25 ± 0.93 | 1.08 ± 0.85 | 0.81 ± 0.73 | 1.44 ± 1.04 | 1.18 ± 1.21 | 1.25 ± 0.75 |
No | 105 (33.1) | 1.57 ± 1.01 | 1.71 ± 0.90 | 1.55 ± 0.98 | 1.13 ± 0.88 | 0.88 ± 0.76 | 1.70 ± 1.00 | 0.40 ± 0.70 | 1.21 ± 0.73 |
p-value | 0.391 | 0.711 | 0.008 | 0.675 | 0.428 | 0.038 | ≤0.001 | 0.640 | |
Employment | |||||||||
Employed | 101 (32.4) | 1.38 ± 1.03 | 1.45 ± 0.93 | 1.11 ± 0.98 | 0.93 ± 0.84 | 0.72 ± 0.71 | 1.38 ± 1.10 | 0.90 ± 1.12 | 1.08 ± 0.73 |
Unemployed | 211 (67.6) | 1.59 ± 0.96 | 1.80 ± 0.87 | 1.67 ± 0.94 | 1.22 ± 0.87 | 0.91 ± 0.76 | 1.65 ± 0.99 | 0.92 ± 1.12 | 1.32 ± 0.74 |
p-value | 0.072 | 0.001 | 0.002 | 0.007 | 0.035 | 0.030 | 0.866 | 0.007 | |
Income, in thousand Korean won (before diagnosis) | |||||||||
< 2000 | 66 (21.7) | 1.46 ± 1.01 | 1.70 ± 0.91 | 1.46 ± 0.92 | 1.17 ± 0.92 | 0.93 ± 0.78 | 1.40 ± 1.09 | 0.75 ± 1.17 | 1.25 ± 0.77 |
2000–4000 | 100 (32.9) | 1.48 ± 0.95 | 1.64 ± 0.88 | 1.35 ± 0.97 | 1.12 ± 0.84 | 0.84 ± 0.71 | 1.58 ± 0.94 | 1.00 ± 1.15 | 1.26 ± 0.73 |
4000–6000 | 91 (29.9) | 1.50 ± 0.97 | 1.73 ± 0.94 | 1.30 ± 0.96 | 1.03 ± 0.83 | 0.77 ± 0.75 | 1.50 ± 1.06 | 0.86 ± 1.04 | 1.20 ± 0.76 |
≥ 6000 | 47 (15.5) | 1.60 ± 1.08 | 1.63 ± 0.92 | 1.27 ± 1.05 | 1.12 ± 0.95 | 0.77 ± 0.74 | 1.67 ± 1.14 | 1.02 ± 1.17 | 1.24 ± 0.76 |
p-value | 0.889 | 0.903 | 0.705 | 0.786 | 0.563 | 0.527 | 0.470 | 0.956 | |
Income, in thousand Korean won (after diagnosis) | |||||||||
< 2000 | 97 (32.2) | 1.55 ± 0.97 | 1.73 ± 0.89 | 1.53 ± 0.90 | 1.26 ± 0.91 | 0.91 ± 0.73a | 1.48 ± 1.05 | 0.88 ± 1.14 | 1.32 ± 0.75 |
2000–4000 | 101 (33.6) | 1.48 ± 0.99 | 1.68 ± 0.86 | 1.35 ± 0.99 | 1.09 ± 0.85 | 0.94 ± 0.79a | 1.64 ± 0.97 | 0.99 ± 1.13 | 1.26 ± 0.76 |
4000–6000 | 70 (23.3) | 1.49 ± 0.96 | 1.64 ± 0.97 | 1.18 ± 0.93 | 0.99 ± 0.84 | 0.62 ± 0.66b | 1.44 ± 1.12 | 0.69 ± 1.00 | 1.10 ± 0.69 |
≥ 6000 | 33 (11.0) | 1.45 ± 1.10 | 1.59 ± 0.94 | 1.12 ± 1.08 | 0.95 ± 0.86 | 0.64 ± 0.68b | 1.55 ± 1.10 | 1.00 ± 1.20 | 1.12 ± 0.76 |
p-value | 0.942 | 0.846 | 0.060 | 0.164 | 0.012 | 0.606 | 0.325 | 0.220 | |
Self-help group | |||||||||
Yes | 31(9.9) | 1.65 ± 0.99 | 1.69 ± 0.91 | 1.21 ± 0.89 | 1.33 ± 0.94 | 0.96 ± 0.82 | 1.67 ± 1.09 | 1.32 ± 1.28 | 1.36 ± 0.81 |
No | 281 (90.1) | 1.49 ± 0.99 | 1.69 ± 0.90 | 1.37 ± 0.97 | 1.09 ± 0.85 | 0.83 ± 0.74 | 1.53 ± 1.03 | 0.86 ± 1.09 | 1.23 ± 0.74 |
p-value | 0.397 | 0.983 | 0.371 | 0.138 | 0.341 | 0.500 | 0.060 | 0.340 |
Needs by psychosocial status and QoL
Multiple regression analysis by needs
Variable | Healthcare staff | Information and education | Psychological problem | Physical symptom | Social support | Hospital service | Religious support | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | T | β | T | β | T | β | T | β | T | β | T | β | T | |
Marital status (ref: Single) | ||||||||||||||
Married | 0.151 | 0.579 | 0.217 | 0.920 | 0.306 | 1.294 | −0.227 | −1.055 | 0.012 | 0.061 | 0.246 | 0.918 | 0.139 | 0.450 |
Separated etc | 0.180 | 0.592 | 0.248 | 0.898 | 0.279 | 1.010 | −0.403 | −1.602 | − 0.060 | − 0.269 | 0.384 | 1.221 | 0.231 | 0.626 |
Religion (ref: Yes) | ||||||||||||||
No | −0.019 | −0.153 | − 0.045 | − 0.392 | 0.198 | 1.727 | − 0.036 | − 0.342 | − 0.038 | −0.415 | 0.163 | 1.249 | −0.737 | −4.904 |
Employment (ref: Yes) | ||||||||||||||
No | 0.216 | 1.583 | 0.272 | 2.202* | 0.201 | 1.628 | 0.171 | 1.512 | −0.012 | −0.119 | 0.174 | 1.241 | −0.233 | −1.436 |
Income (ref: ≥600) | ||||||||||||||
400–600 | 0.080 | 0.374 | 0.064 | 0.330 | 0.102 | 0.531 | 0.099 | 0.563 | 0.014 | 0.091 | −0.049 | −0.222 | −0.117 | − 0.467 |
200–400 | − 0.039 | −0.189 | − 0.071 | − 0.384 | 0.127 | 0.683 | 0.051 | 0.300 | 0.214 | 1.438 | − 0.100 | −0.474 | 0.078 | 0.320 |
< 200 | −0.118 | −0.554 | − 0.157 | − 0.810 | 0.164 | 0.845 | 0.046 | 0.259 | 0.109 | 0.700 | −0.369 | −1.678 | − 0.189 | − 0.746 |
Age (ref: ≤39) | ||||||||||||||
40–49 | 0.299 | 1.634 | 0.253 | 1.523 | 0.189 | 1.139 | 0.284 | 1.877 | 0.100 | 0.747 | 0.331 | 1.742 | 0.245 | 1.120 |
50–59 | 0.339 | 1.844 | 0.267 | 1.597 | 0.161 | 0.962 | 0.381 | 2.506* | 0.138 | 1.024 | 0.249 | 1.304 | 0.291 | 1.321 |
≥ 60 | 0.195 | 0.786 | 0.174 | 0.771 | −0.068 | − 0.301 | 0.057 | 0.276 | −0.027 | − 0.150 | 0.094 | 0.364 | −0.006 | − 0.021 |
Family history (ref: No) | ||||||||||||||
Yes | − 0.196 | − 0.928 | −0.217 | −1.131 | − 0.006 | −0.029 | − 0.053 | −0.304 | 0.012 | 0.079 | −0.412 | −1.847 | −0.192 | − 0.747 |
TNM stage (ref: 0) | ||||||||||||||
I | 0.325 | 0.941 | 0.162 | 0.515 | 0.270 | 0.859 | −0.251 | −0.876 | 0.108 | 0.432 | 0.462 | 1.300 | 0.493 | 1.207 |
II | 0.440 | 1.239 | 0.267 | 0.829 | 0.453 | 1.404 | −0.061 | −0.208 | 0.306 | 1.185 | 0.611 | 1.674 | 0.671 | 1.594 |
III + IV | 0.280 | 0.678 | 0.242 | 0.644 | 0.671 | 1.788 | −0.061 | − 0.177 | 0.375 | 1.251 | 0.570 | 1.342 | 0.592 | 1.210 |
Multiplicity (ref: No) | ||||||||||||||
Yes | 0.351 | 2.265* | 0.179 | 1.273 | 0.187 | 1.327 | 0.269 | 2.092* | 0.110 | 0.978 | 0.190 | 1.190 | 0.338 | 1.838 |
HER2 (ref: No) | ||||||||||||||
Yes | 0.078 | 0.374 | 0.335 | 1.763 | 0.283 | 1.488 | 0.061 | 0.349 | 0.052 | 0.345 | 0.242 | 1.124 | −0.017 | − 0.069 |
Breast surgery (ref: BCS) | ||||||||||||||
Mastectomy | 0.106 | 0.598 | 0.013 | 0.080 | −0.070 | −0.434 | − 0.063 | −0.429 | − 0.075 | −0.578 | 0.127 | 0.691 | 0.195 | 0.922 |
(NA)SSM | 0.057 | 0.224 | −0.188 | − 0.810 | − 0.140 | − 0.601 | 0.272 | 1.284 | − 0.039 | − 0.208 | – | – | − 0.157 | − 0.520 |
Axillary surgery (ref: SLNB) | ||||||||||||||
ALND | 0.061 | 0.419 | 0.023 | 0.172 | − 0.071 | − 0.537 | 0.017 | 0.138 | − 0.135 | −1.281 | 0.078 | 0.521 | −0.125 | − 0.724 |
Chemotherapy (ref: No) | ||||||||||||||
Yes | − 0.159 | − 1.003 | 0.153 | 1.066 | − 0.075 | − 0.520 | 0.023 | 0.176 | 0.008 | 0.066 | −0.088 | − 0.539 | − 0.205 | − 1.087 |
Hormonal Tx (ref: No) | ||||||||||||||
Yes | − 0.047 | −0.359 | − 0.019 | −0.163 | − 0.027 | −0.226 | − 0.177 | −1.635 | −0.062 | − 0.655 | 0.077 | 0.569 | 0.117 | 0.753 |
Radiation Tx (ref: No) | ||||||||||||||
Yes | 0.348 | 1.773 | 0.181 | 1.014 | −0.084 | − 0.471 | 0.169 | 1.042 | −0.091 | − 0.637 | 0.217 | 1.071 | −0.020 | − 0.084 |
Target Tx (ref: No) | ||||||||||||||
Yes | − 0.002 | − 0.007 | − 0.292 | −1.348 | −0.116 | − 0.533 | 0.080 | 0.406 | 0.134 | 0.772 | 0.001 | 0.002 | 0.205 | 0.722 |
Adjuvant treatment (ref: During) | ||||||||||||||
After | 0.142 | 1.045 | −0.042 | −0.339 | 0.082 | 0.665 | −0.010 | −0.089 | − 0.088 | −0.893 | 0.086 | 0.620 | −0.085 | −0.523 |
others | 0.203 | 1.196 | −0.136 | −0.884 | 0.196 | 1.269 | 0.029 | 0.204 | 0.034 | 0.274 | −0.077 | −0.441 | 0.008 | 0.042 |
Stress (ref: Little) | ||||||||||||||
A little | 0.548 | 2.948† | 0.544 | 3.225† | 0.541 | 3.202† | 0.422 | 2.740† | 0.402 | 2.977† | 0.510 | 2.668† | 0.147 | 0.667 |
High | 1.215 | 5.271‡ | 1.208 | 5.778‡ | 1.130 | 5.404‡ | 1.176 | 6.166‡ | 0.794 | 4.743‡ | 1.299 | 5.478‡ | 0.330 | 1.212 |
Very high | 1.481 | 5.074‡ | 1.209 | 4.565‡ | 1.338 | 5.048‡ | 1.171 | 4.847‡ | 0.809 | 3.821‡ | 1.350 | 4.502‡ | 0.092 | 0.265 |
Despair (ref: No) | ||||||||||||||
Yes | 0.049 | 0.306 | − 0.011 | − 0.073 | 0.276 | 1.900 | 0.271 | 2.046 | 0.224 | 1.907 | 0.165 | 0.995 | 0.035 | 0.180 |
Thought of suicide (ref: No) | ||||||||||||||
Yes | 0.076 | 0.423 | 0.054 | 0.333 | 0.092 | 0.562 | −0.029 | −0.195* | 0.105 | 0.798 | −0.065 | −0.350 | 0.028 | 0.127 |
EQ5-D (ref: No problem) | ||||||||||||||
Problem | −0.053 | −0.356 | 0.033 | 0.242 | 0.057 | 0.418 | 0.090 | 0.730 | 0.010 | 0.096 | 0.116 | 0.755 | 0.185 | 1.046 |
Adjusted | 0.138 | 0.158 | 0.247 | 0.245 | 0.167 | 0.182 | 0.092 | |||||||
F-value | 2.433 | 2.687 | 3.958 | 3.909 | 2.794 | 2.984 | 1.896 | |||||||
P-value | ≤0.001 | ≤0.001 | ≤0.001 | ≤0.001 | ≤0.001 | ≤0.001 | 0.004 |