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Erschienen in:

17.06.2022 | Neuromuscular Disorders (C Fournier, Section Editor)

Update on Paraneoplastic Neuromuscular Disorders

verfasst von: Andrés M. De León, MD, Taylor B. Harrison, MD, Rocio Garcia-Santibanez, MD

Erschienen in: Current Treatment Options in Neurology | Ausgabe 7/2022

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Abstract

Purpose of Review

To review the clinical presentation and diagnosis of different paraneoplastic neuromuscular disorders and the available data on their treatment.

Recent Findings

Paraneoplastic neuromuscular disorders are rare, and their treatment needs a multidisciplinary approach. Given their rarity, there are no clinical trials specifically looking at these disorders and thus treatment is guided by management of autoimmune neuromuscular syndromes.

Summary

Paraneoplastic neuromuscular disorders can affect the entire axis of the peripheral nervous system including disorders of muscle, neuromuscular junction, peripheral nerve, and the sensory or motor neurons. Early detection and treatment of the underlying malignancy is key to the effective management of these conditions. Immune therapy can be offered but the evidence is strongest for treatment of muscle and neuromuscular junction diseases. Additional research is needed to better understand and treat paraneoplastic disorders of the nerves as well as the sensory and motor neurons.
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Metadaten
Titel
Update on Paraneoplastic Neuromuscular Disorders
verfasst von
Andrés M. De León, MD
Taylor B. Harrison, MD
Rocio Garcia-Santibanez, MD
Publikationsdatum
17.06.2022
Verlag
Springer US
Erschienen in
Current Treatment Options in Neurology / Ausgabe 7/2022
Print ISSN: 1092-8480
Elektronische ISSN: 1534-3138
DOI
https://doi.org/10.1007/s11940-022-00722-7

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