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Current Treatment Options in Gastroenterology

Erschienen in:

13.08.2020 | Inflammatory Bowel Disease (G Lichtenstein, Section Editor)

Update on Pregnancy in Patients with IBD

verfasst von: Rachel W. Winter, MD, MPH, Sonia Friedman, MD

Erschienen in: Current Treatment Options in Gastroenterology | Ausgabe 3/2020

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Abstract

Purpose of review

This review summarizes the most current clinical research and latest clinical guidelines in managing inflammatory bowel disease (IBD) before, during, and after pregnancy.

Recent findings

Recent guidelines emphasize the safety of thiopurines and biologics during pregnancy and nursing. Patients should be in remission for 3–6 months prior to conceiving and remain in remission to decrease the risk of poor pregnancy outcomes. Fertility is decreased in women with active IBD and in women who have had anal or rectal resection. Women with IBD, especially those with Crohn’s disease (CD) who have had surgery, have an increased time to pregnancy. Women with CD and ulcerative colitis who need assisted reproduction have a decreased chance of a live birth compared with women in the general population. Indications for caesarian section include active perianal disease.

Summary

Most IBD medications are safe during pregnancy and should be continued to ensure remission. Preconception counseling and a multidisciplinary team approach are the best ways to support a healthy pregnancy and delivery.

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Titel: Update on Pregnancy in Patients with IBD
verfasst von: Rachel W. Winter, MD, MPH
Sonia Friedman, MD
Publikationsdatum: 13.08.2020
Verlag: Springer US
Erschienen in: Current Treatment Options in Gastroenterology / Ausgabe 3/2020
Print ISSN: 1092-8472
Elektronische ISSN: 1534-309X
DOI: https://doi.org/10.1007/s11938-020-00303-0

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Update Innere Medizin