Urethral bulking agents for the treatment of female stress urinary incontinence

Excerpt

In the current general scenario on the use of mesh surgery for the treatment of pelvic floor dysfunction, the role of traditional mid-urethral slings (MUS) for the treatment of female stress urinary incontinence (SUI) is highly debated [1]. However, despite the warning published in 2018 in the UK and the NICE guidelines proposed a few months ago, it is evident that placement of MUS can be considered the gold standard for the treatment of SUI [2]. MUS show a long-lasting efficacy well demonstrated also with a long-term follow-up, with a relatively low complication rate [3, 4]. In 2018, a very large original study published in JAMA using a national population-based retrospective cohort of 90,057 women from the National Health Service in England found a low sling removal rate (3.3%) and a low SUI recurrence rate (4.5%) after MUS insertion even after 9 years. …