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Erschienen in: Rheumatology International 12/2017

18.08.2017 | Review on RMDs

Urolithiasis as an extraarticular manifestation of ankylosing spondylitis

verfasst von: Cengiz Korkmaz, Döndü Üsküdar Cansu, John A. Sayer

Erschienen in: Rheumatology International | Ausgabe 12/2017

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Abstract

Ankylosing spondylitis (AS) affects sacroiliac and axial joints as well as extraarticular organs, such as the eye, lung, bowel, and heart. Although examples of renal involvement in AS, such as IgA nephropathy, amyloidosis, and glomerulonephritis, have been reported, it has not been emphasized that urolithiasis is frequently formed in the clinical course of AS. Growing evidence indicates that urolithiasis may be observed in AS patients and is more frequent than other extraarticular features. In this review, we will discuss frequency and predictors of AS-related urolithiasis and summarize the possible underlying genetic and biochemical mechanisms. We believe an increased awareness of urolithiasis as a complication of AS will encourage future studies that will shed light on disease mechanisms and preventative therapies.
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Metadaten
Titel
Urolithiasis as an extraarticular manifestation of ankylosing spondylitis
verfasst von
Cengiz Korkmaz
Döndü Üsküdar Cansu
John A. Sayer
Publikationsdatum
18.08.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Rheumatology International / Ausgabe 12/2017
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-017-3788-0

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