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Erschienen in: Allergo Journal 8/2018

11.12.2018 | Asthma bronchiale | Leitlinien

EAACI/GA2LEN/EDF/WAO-Leitlinie für die Definition, Klassifikation, Diagnose und das Management der Urtikaria — konsentierte, deutschsprachige Übersetzung

Leitlinie der European Academy of Allergology and Clinical Immunology (EAACI), des Global Allergy and Asthma European Network (GA2LEN), des European Dermatology Forum (EDF) und der World Allergy Organization (WAO)

verfasst von: Prof. Dr. Torsten Zuberbier, Werner Aberer, Riccardo Asero, Amir Hamzah Abdul Latiff, Diane Baker, Barbara Ballmer-Weber, Jonathan A. Bernstein, Carsten Bindslev-Jensen, Zenon Brzoza, Roberta Buense Bedrikow, Giorgio Walter Canonica, Martin K. Church, Timothy Craig, Inna Vladimirovna Danilycheva, Corinna Dressler, Luis Felipe Ensina, Ana Giménez-Arnau, Kiran Godse, Margarida Goncalo, Clive Grattan, Jacques Hebert, Michihiro Hide, Allen Kaplan, Alexander Kapp, Constance H. Katelaris, Emek Kocatürk, Kanokvalai Kulthanan, Désirée Larenas-Linnemann, Tabi A. Leslie, Markus Magerl, Pascale Mathelier-Fusade, Raisa Y. Meshkova, Martin Metz, Alexander Nast, Eustachio Nettis, Hanneke Oude-Elberink, Stefanie Rosumeck, Sarbjit S. Saini, Mario Sánchez-Borges, Peter Schmid-Grendelmeier, Petra Staubach, Gordon Sussman, Elias Toubi, Gino A. Vena, Christian Vestergaard, Bettina Wedi, Ricardo N. Werner, Zuotao Zhao, Marcus Maurer, Randolf Brehler, Knut Brockow, Joachim Fluhr, Jürgen Grabbe, Eckard Hamelmann, Karin Hartmann, Thilo Jakob, Hans Merk, Markus Ollert, Hagen Ott, Imke Reese, Franziska Rueff, Thomas Werfel

Erschienen in: Allergo Journal | Ausgabe 8/2018

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Abstract

Diese evidenz- und konsensbasierte Leitlinie wurde entsprechend den Methoden der Cochrane und der Grading of Recommendations Assessment, Development and Evaluation (GRADE)-Arbeitsgruppen entwickelt. Die Leitlinien-Konferenz fand am 1. Dezember 2016 statt. Sie ist eine gemeinsame Initiative der European Academy of Allergology and Clinical Immunology (EAACI), dem von der EU gegründeten Global Allergy and Asthma European Network (GA2LEN), dem European Dermatology Forum (EDF) und der World Allergy Organization (WAO) mit 48 teilnehmenden Delegierten aus 42 nationalen und internationalen Gesellschaften.
Die Leitlinie ist von der European Union of Medical Specialists (UEMS) akzeptiert worden. Urtikaria ist eine häufige, mastzellabhängige Erkrankung, die mit Quaddeln, Angioödemen oder beidem einhergeht. Die Lebenszeitprävalenz der akuten Urtikaria liegt bei circa 20 %. Chronische spontane Urtikaria (CSU) und andere chronische Formen der Urtikaria sind belastend, beeinträchtigen die Lebensqualität und haben einen negativen Einfluss auf die Leistungsfähigkeit in Beruf und Schule. Diese Leitlinie umfasst die Definition und Klassifikation der Urtikaria unter Berücksichtigung der jüngsten Fortschritte in der Identifikation von Ursachen, Auslösefaktoren und Pathomechanismen. Darüber hinaus skizziert sie evidenzbasierte, diagnostische und therapeutische Ansätze für die verschiedenen Subtypen der Urtikaria.
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Metadaten
Titel
EAACI/GA2LEN/EDF/WAO-Leitlinie für die Definition, Klassifikation, Diagnose und das Management der Urtikaria — konsentierte, deutschsprachige Übersetzung
Leitlinie der European Academy of Allergology and Clinical Immunology (EAACI), des Global Allergy and Asthma European Network (GA2LEN), des European Dermatology Forum (EDF) und der World Allergy Organization (WAO)
verfasst von
Prof. Dr. Torsten Zuberbier
Werner Aberer
Riccardo Asero
Amir Hamzah Abdul Latiff
Diane Baker
Barbara Ballmer-Weber
Jonathan A. Bernstein
Carsten Bindslev-Jensen
Zenon Brzoza
Roberta Buense Bedrikow
Giorgio Walter Canonica
Martin K. Church
Timothy Craig
Inna Vladimirovna Danilycheva
Corinna Dressler
Luis Felipe Ensina
Ana Giménez-Arnau
Kiran Godse
Margarida Goncalo
Clive Grattan
Jacques Hebert
Michihiro Hide
Allen Kaplan
Alexander Kapp
Constance H. Katelaris
Emek Kocatürk
Kanokvalai Kulthanan
Désirée Larenas-Linnemann
Tabi A. Leslie
Markus Magerl
Pascale Mathelier-Fusade
Raisa Y. Meshkova
Martin Metz
Alexander Nast
Eustachio Nettis
Hanneke Oude-Elberink
Stefanie Rosumeck
Sarbjit S. Saini
Mario Sánchez-Borges
Peter Schmid-Grendelmeier
Petra Staubach
Gordon Sussman
Elias Toubi
Gino A. Vena
Christian Vestergaard
Bettina Wedi
Ricardo N. Werner
Zuotao Zhao
Marcus Maurer
Randolf Brehler
Knut Brockow
Joachim Fluhr
Jürgen Grabbe
Eckard Hamelmann
Karin Hartmann
Thilo Jakob
Hans Merk
Markus Ollert
Hagen Ott
Imke Reese
Franziska Rueff
Thomas Werfel
Publikationsdatum
11.12.2018
Verlag
Springer Medizin
Erschienen in
Allergo Journal / Ausgabe 8/2018
Print ISSN: 0941-8849
Elektronische ISSN: 2195-6405
DOI
https://doi.org/10.1007/s15007-018-1751-3

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Urtikaria CME-Kurs
CME: 2 Punkte

Die akute Urtikaria (AU) ist die häufigste Ursache einer Quaddelbildung. Definitionsgemäß besteht sie nicht länger als sechs Wochen. Sie kann in jedem Lebensalter auftreten und wird häufiger bei atopischer Diathese gesehen. Die akute spontane Urtikaria wird von den induzierbaren Formen unterschieden. In dieser CME-Übersichtsarbeit werden Klinik, Differenzialdiagnose, mögliche Auslöser und therapeutische Strategien aufgezeigt. Im Kindesalter wie im Erwachsenenalter sind virale Infekte sehr häufig mit einer akuten Urtikaria assoziiert, während Medikamente und Nahrungsmittel seltener als Auslöser beschrieben werden. Oftmals sind jedoch auch mehrere Trigger gleichzeitig vorhanden. Therapeutisch kommen vor allem orale nicht sedierende H1-Antihistaminika zum Einsatz. Bei einigen Betroffenen wird auch eine begleitende, kurzfristige Gabe von Glukokortikosteroiden nötig.

Das Handbuch für molekulare Allergologie 2.0: Update zu relevanten neuen Inhalten

CME: 4 Punkte

Der erste Leitfaden zur molekularen Allergologie wurde 2016 veröffentlicht und wurde schnell zu einer wichtigen Referenz für viele Kliniker und Wissenschaftler weltweit. Die rasante Entwicklung unseres Wissens über Allergenmoleküle sowie die Verfügbarkeit neuer Assays und neuer klinischer Studien machten eine Aktualisierung des Leitfadens erforderlich. In einer konzertierten Aktion von fast 100 Autoren wurden alle Kapitel der ersten Auflage überarbeitet und neue Kapitel hinzugefügt, wodurch der aktuellste, frei verfügbare Leitfaden zur molekularen Allergologie für die tägliche Praxis entstand. Die CME-Fortbildung gibt einen Überblick über die wichtigsten Neuerungen des Molecular Allergology User’s Guide 2.0, MAUG 2.0 (Ausgabe 2022).