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Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases 1/2005

01.01.2005 | Concise Article

Use of convalescent plasma therapy in SARS patients in Hong Kong

verfasst von: Y. Cheng, R. Wong, Y. O. Y. Soo, W. S. Wong, C. K. Lee, M. H. L. Ng, P. Chan, K. C. Wong, C. B. Leung, G. Cheng

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 1/2005

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Abstract

In order to evaluate the efficacy of convalescent plasma therapy in the treatment of patients with severe acute respiratory syndrome (SARS), 80 SARS patients were given convalescent plasma at Prince of Wales Hospital, Hong Kong, between 20 March and 26 May 2003. Good outcome was defined as discharge by day 22 following the onset of SARS symptoms. Poor outcome was defined as death or hospitalization beyond 22 days. A higher day-22 discharge rate was observed among patients who were given convalescent plasma before day 14 of illness (58.3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001).
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Metadaten
Titel
Use of convalescent plasma therapy in SARS patients in Hong Kong
verfasst von
Y. Cheng
R. Wong
Y. O. Y. Soo
W. S. Wong
C. K. Lee
M. H. L. Ng
P. Chan
K. C. Wong
C. B. Leung
G. Cheng
Publikationsdatum
01.01.2005
Erschienen in
European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 1/2005
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-004-1271-9

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