Erschienen in:
20.06.2017 | Urologic Oncology
Usefulness of Mapping Biopsy in the Treatment of Penoscrotal Extramammary Paget’s Disease
verfasst von:
Curtis A. Pettaway, MD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 11/2017
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Excerpt
Park et al. report their experience in the management of extramammary Paget’s Disease (EMPD) of the penoscrotal region and specifically compare outcomes among cohorts of men with the disease who either did or did not undergo mapping biopsies prior to their definitive surgical procedure. The rationale for the study and this comparison is that Paget’s disease initially spreads insidiously through the epidermis, sometimes in a single-cell fashion, and establishing the diagnosis can be very difficult subsequent to intraoperative frozen sections. Thus, several studies have described the use of outpatient mapping biopsies under more permanent section pathology techniques to facilitate the diagnosis and to ‘clear’ the surgical margins (references 19–21 in the article). This should theoretically lead to a lower incidence of positive frozen section margins intraoperatively, a lower incidence of positive permanent section margins, and lower recurrence rates for patients. …
