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19.03.2018 | Review Article

Using proteomics as a powerful tool to develop a vaccine against Mediterranean visceral leishmaniasis

Erschienen in: Journal of Parasitic Diseases | Ausgabe 2/2018

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Abstract

Visceral leishmaniasis (VL) is a tropical infectious disease, which is called Mediterranean visceral leishmaniasis (MVL) in the Mediterranean area. In spite of many attempts, no effective commercial vaccine exists for MVL. To find new targets for developing antileishmanial vaccines, knowing parasite antigens that provoke the immune system are on demand. Nowadays, proteomics methods are defined as approaches for analysis of protein profiling of different cells. Within this framework, detection of new antigens is becoming more facilitated. In this review, we aimed to introduce possible targets using proteomics so; they could be used as candidates for developing vaccines against MVL. It can shed new light in the near future on the development of promising vaccines for MVL.

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Titel: Using proteomics as a powerful tool to develop a vaccine against Mediterranean visceral leishmaniasis
Publikationsdatum: 19.03.2018
Erschienen in: Journal of Parasitic Diseases / Ausgabe 2/2018
Print ISSN: 0971-7196
Elektronische ISSN: 0975-0703
DOI: https://doi.org/10.1007/s12639-018-0986-y

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