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Erschienen in: Abdominal Radiology 11/2020

06.04.2020 | Kidneys, Ureters, Bladder, Retroperitoneum

Using texture analysis as a predictive factor of subtype, grade and stage of renal cell carcinoma

verfasst von: Servan Yaşar, Nuray Voyvoda, Bekir Voyvoda, Tülay Özer

Erschienen in: Abdominal Radiology | Ausgabe 11/2020

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Abstract

Objective

The aim of this study was to evaluate the correlation between the tissue texture analysis and the histological subtypes, grade and stage of the disease in patients with renal cell carcinoma (RCC).

Materials and methods

Seventy-seven patients who underwent computed tomography due to renal mass and diagnosed with RCC as a result of pathological examination were retrospectively analyzed. In these analyses, the demographic characteristics, pathological and radiological findings of the patients were evaluated. The masses were introduced to the Radiomics extension of the software and the first- and second-order texture analysis parameters were obtained. The correlation of these parameters with histological subtype, Fuhrman grade and TNM stage was investigated.

Results

In the comparison of the Radiomics values by stages, “minimum”, “Long Run Low Gray-level Emphasis” values were higher in the stage 1–2 group, while “Energy”, “Total energy”, “Range”, “Joint Average”, “Sum Average”, “Gray-Level Non-Uniformity”, “Short-Run High Gray-level Emphasis “, “Run Length Non-Uniformity “and “High Gray-Level Run Emphasis “values were higher in the stage 3–4 group. Of these parameters, only “Gray-Level Non-Uniformity” and “Run Length Non-Uniformity’’ values were significantly lower in tumors with low Fuhrman grade (1–2) and low TNM stage (1–2). There was no statistically significant correlation between the parameters found to be significant in histological subtype differentiation and Fuhrman grade and TNM stage.

Conclusion

This study demonstrates that “Gray-Level Non-Uniformity” and “Run Length Non-Uniformity “parameters in the texture analysis method can be used to evaluate the prognosis in patients with RCC.
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Metadaten
Titel
Using texture analysis as a predictive factor of subtype, grade and stage of renal cell carcinoma
verfasst von
Servan Yaşar
Nuray Voyvoda
Bekir Voyvoda
Tülay Özer
Publikationsdatum
06.04.2020
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 11/2020
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-020-02495-6

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