01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Utility of routine ultrasonography follow-up after total thyroidectomy in patients with papillary thyroid carcinoma: a single-center study
- Zeitschrift:
- BMC Medical Imaging > Ausgabe 1/2018
Electronic supplementary material
Background
Methods
Patients
Total thyroidectomy
Follow-up neck ultrasonography
Determination of tumor recurrence/persistence
Statistical analysis
Results
T stage
|
Interval of the last follow-up US (month: mean ± SD, range)
|
Tumor recurrence/persistence (%)
|
T1a (
n = 278)
|
53.7 ± 22.9 (5-90)
|
6 (2.2)
|
T1b (
n = 167)
|
55.4 ± 23.1 (8-91)
|
16 (9.6)
|
T2 (
n = 71)
|
57.0 ± 20.2 (10-84)
|
8 (11.3)
|
T3a (
n = 7)
|
64.6 ± 23.5 (14-84)
|
1 (14.3)
|
T3b (n = 2)
|
54 ± 2.8 (52-56)
|
0
|
T4a (
n = 0)
|
NA
|
NA
|
T4b (
n = 0)
|
NA
|
NA
|
N stage
|
Interval of the last follow-up US (month: mean ± SD, range)
|
Tumor recurrence/persistence (%)
|
N0 (
n = 253)
|
53.1 ± 22.9 (5-90)
|
2.0 (5)
|
N1a (
n = 226)
|
55.1 ± 22.7 (6-91)
|
8.0 (18)
|
N1b (
n = 46)
|
60.9 ± 21.9 (0-89)
|
17.4 (8)
|
Items
|
Odds ratio
a
|
P value
|
---|---|---|
Patient age
|
0.96 (0.93, 0.98)
|
0.011
|
Sex
|
1.20 (0.38, 3.84)
|
0.759
|
Size of primary PTC
|
1.00 (0.92, 1.10)
|
0.932
|
Location of primary PTC
|
0.56 (0.27, 1.20)
|
0.136
|
T stage
|
1.62 (0.64, 4.10)
|
0.305
|
N stage
|
2.41 (1.27, 4.58)
|
0.007
|
Multiplicity
|
1.88 (0.85, 4.17)
|
0.119
|
Interval of the last follow-up US
|
0.96 (0.92, 1.01)
|
0.058
|
Number of follow-up US session
|
1.49 (0.91, 2.46)
|
0.116
|
Number of follow-up US sessions
|
Interval of the last follow-up US (month: mean ± SD, range)
|
Tumor recurrence/persistence (%)
|
---|---|---|
1 (
n = 58)
|
13.9 ± 11.8 (5-58)
|
3 (5.2)
|
2 (
n = 57)
|
26.1 ± 14.8 (10-73)
|
7 (12.3)
|
3 (
n = 29)
|
40.5 ± 13.3 (19-70)
|
1 (3.4)
|
4 (
n = 64)
|
55.3 ± 11.2 (30-81)
|
4 (6.3)
|
5 (
n = 169)
|
64.1 ± 9.4 (45-90)
|
6 (3.6)
|
6 (
n = 114)
|
71.8 ± 6.7 (55-89)
|
6 (5.3)
|
7 (
n = 28)
|
78.0 ± 9.0 (55-91)
|
2 (7.1)
|
8 (
n = 4)
|
82.0 ± 0.8 (81-83)
|
1 (25)
|
9 (
n = 2)
|
82.5 ± 2.1 (81-84)
|
1 (50)
|
Items
|
A
z value
a
|
Sensitivity
|
Specificity
|
PPV
|
NPV
|
Cut off
|
P value
|
---|---|---|---|---|---|---|---|
(%)
|
(%)
|
(%)
|
(%)
|
||||
Number of session
|
0.513 (0.469, 0.556)
|
32.3
|
78.7
|
8.7
|
94.9
|
2
|
0.828
|
Interval
|
0.514 (0.470, 0.558)
|
38.7
|
77.5
|
9.8
|
95.3
|
39
|
0.814
|