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Medical Microbiology and Immunology
Erschienen in: Medical Microbiology and Immunology 6/2014

01.12.2014 | Review

Vaccination against infectious diseases: What is promising?

verfasst von: Hans Wilhelm Doerr, Annemarie Berger

Erschienen in: Medical Microbiology and Immunology | Ausgabe 6/2014

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Abstract

Vaccination has proven to be one of the best weapons protecting the mankind against infectious diseases. Along with the huge progress in microbiology, numerous highly efficacious and safe vaccines have been produced by conventional technology (cultivation), by the use of molecular biology (genetic modification), or by synthetic chemistry. Sterilising prevention is achieved by the stimulation of antibody production, while the stimulation of cell-mediated immune responses may prevent the outbreak of disease in consequence of an acute or reactivated infection. From several examples, two rules are deduced to evaluate the perspectives of future vaccine developments: They are promising, if (1) the natural infectious disease induces immunity or (2) passive immunisation (transfer of antibodies, adoptive transfer of lymphocytes) is successful in preventing infection.
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Metadaten
Titel
Vaccination against infectious diseases: What is promising?
verfasst von
Hans Wilhelm Doerr
Annemarie Berger
Publikationsdatum
01.12.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Medical Microbiology and Immunology / Ausgabe 6/2014
Print ISSN: 0300-8584
Elektronische ISSN: 1432-1831
DOI
https://doi.org/10.1007/s00430-014-0346-1

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