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Erschienen in:
01.09.2009 | Original Paper
Vagus nerve stimulation in children with intractable epilepsy: indications, complications and outcome
Erschienen in: Child's Nervous System | Ausgabe 9/2009
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Purpose
To analyze the indication, complications and outcome of vagus nerve stimulation in intractable childhood epilepsy.
Materials and methods
We retrospectively reviewed the data of 69 children who had insertion of vagal nerve stimulator (VNS) between June 1995 and August 2006 for medically intractable epilepsy. Outcome was based on the Engel's classification. Statistical analysis of the data was also done to see if any of the parameters significantly influenced the outcome.
Result
Thirty-eight patients (55.08 %) had a satisfactory outcome (Engel class I, II or III), and in 31 patients (44.92 %), there was no worthwhile improvement of seizures (Engel class IV). There was no statistical significance between the type of seizure and outcome (Fisher's exact test, p = 0.351). Statistical analysis also showed that the following parameters did not significantly influence the outcome (p > 0.05): age at insertion of VNS, age of first fit, duration between first fit and insertion of VNS and the length of follow-up. Complications included infection, lead fracture, fluid collection around the stimulator, neck pain and difficulty swallowing.
Conclusion
Vagus nerve stimulation is a relatively safe and potentially effective treatment for children with medically intractable epilepsy.