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16.06.2023

Valerian for Insomnia on Subjective and Objective Sleep Parameters: a Meta-analysis of Randomized Controlled Trials

verfasst von: Xu Zhang, Yanying Lu, Feiyan Lv, Yan Hu, Zhentao Yao, Yulong Wu, Fuzhi Lian, Jun Yang, Xianrong Xu

Erschienen in: Current Sleep Medicine Reports | Ausgabe 3/2023

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Abstract

Purpose of Review

This systematic review and meta-analysis aimed to assess the effects of valerian intervention for insomnia on both subjective and objective sleep parameters.

Recent Findings

Twenty-one RCTs with a total of 1433 participants were retrieved after searching on 6 electronic databases. The results indicated that, for subjective parameters, valerian may have a small to moderate effects on PSQI score (standardized mean differences (SMD), −1.21; 95% CI [−1.92 to −0.51]), self-reported dichotomous outcome of sleep quality (risk ratio (RR) =1.37; 95% CI [1.13 to 1.68]), and self-reported sleep duration (RR=1.27; 95% CI [1.02 to 1.57]). For objective parameters, valerian only have significant effect on the length of non-rapid eye movement (NREM) stage 3 (SMD= 0.89; 95% CI [0.35 to 1.43]) of the patients. Heterogeneity was mainly due to varied study designs, especially in preparation, outcomes measured, duration of follow-up, and populations.

Summary

Valerian intervention for insomnia may improve PSQI scores, subjective dichotomous outcomes of sleep quality and duration, and time of NREM stages 3.
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Metadaten
Titel
Valerian for Insomnia on Subjective and Objective Sleep Parameters: a Meta-analysis of Randomized Controlled Trials
verfasst von
Xu Zhang
Yanying Lu
Feiyan Lv
Yan Hu
Zhentao Yao
Yulong Wu
Fuzhi Lian
Jun Yang
Xianrong Xu
Publikationsdatum
16.06.2023
Verlag
Springer International Publishing
Erschienen in
Current Sleep Medicine Reports / Ausgabe 3/2023
Elektronische ISSN: 2198-6401
DOI
https://doi.org/10.1007/s40675-023-00259-4

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