Skip to main content
Erschienen in: Supportive Care in Cancer 3/2017

31.10.2016 | Original Article

Validity and reliability of the Greek version of the xerostomia questionnaire in head and neck cancer patients

verfasst von: Pinelopi Theopisti Memtsa, Maria Tolia, Ioannis Tzitzikas, Ioannis Bizakis, Kyriaki Pistevou-Gombaki, Martha Charalambidou, Chrysoula Iliopoulou, George Kyrgias

Erschienen in: Supportive Care in Cancer | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Xerostomia after radiation therapy for head and neck (H&N) cancer has serious effects on patients’ quality of life. The purpose of this study was to validate the Greek version of the self-reported eight-item xerostomia questionnaire (XQ) in patients treated with radiotherapy for H&N cancer.

Methods

The XQ was translated into Greek and administered to 100 XQ patients. An exploratory factor analysis was performed. Reliability measures were calculated. Several types of validity were evaluated. The observer-rated scoring system was also used.

Results

The mean XQ value was 41.92 (SD 22.71). Factor analysis revealed the unidimensional nature of the questionnaire. High reliability measures (ICC, Cronbach’s α, Pearson coefficients) were obtained. Patients differed statistically significantly in terms of XQ score, depending on the RTOG/EORTC classification.

Conclusion

The Greek version of XQ is valid and reliable. Its score is well related to observer’s findings and it can be used to evaluate the impact of radiation therapy on the subjective feeling of xerostomia.
Fußnoten
1
Cicchetti, DV (1994) Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychological Assessment 6: 284–290.
 
2
Over the 95th (pre-post) difference percentile. Mean difference in the 0–10 scale: 0.064 ± 0.21
 
Literatur
2.
Zurück zum Zitat Eisbruch A, Ship JA, Dawson LA, Kim HM et al. (2003) Salivary gland Eisbruch A, Ship JA, Dawson LA, Kim HM et al. (2003) Salivary gland
3.
Zurück zum Zitat Eisbruch A, Ship JA, Terrell JE, Martel MK, Kim M (1999) Assessment of the quality of life of patients with head and neck cancer irradiated with parotid sparing or standard techniques. Grant protocol # UMCC 9759. Eisbruch A, Ship JA, Terrell JE, Martel MK, Kim M (1999) Assessment of the quality of life of patients with head and neck cancer irradiated with parotid sparing or standard techniques. Grant protocol # UMCC 9759.
4.
Zurück zum Zitat Pellegrino F, Groff E, Bastiani L, Fattori B, Sotti G (2015) Assessment of radiation-induced xerostomia: validation of the Italian version of the xerostomia questionnaire in head and neck cancer patients. Support Care Cancer 23:925–932CrossRefPubMed Pellegrino F, Groff E, Bastiani L, Fattori B, Sotti G (2015) Assessment of radiation-induced xerostomia: validation of the Italian version of the xerostomia questionnaire in head and neck cancer patients. Support Care Cancer 23:925–932CrossRefPubMed
5.
Zurück zum Zitat Langendijk JA, Doornaert P, Verdonack-de Leeuw IM, Leemans CR, Aaronson NK, Slotman BJ (2008) Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy. J Clin Oncol 26:3770–3776CrossRefPubMed Langendijk JA, Doornaert P, Verdonack-de Leeuw IM, Leemans CR, Aaronson NK, Slotman BJ (2008) Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy. J Clin Oncol 26:3770–3776CrossRefPubMed
6.
Zurück zum Zitat Eisbruch A, Hyungjin M, Terrell J, March L, Dawson L, Ship JA (2001) Xerostomia and its predictors following parotid-sparing irradiation of head and neck cancer. Head Neck 50:695–704 Eisbruch A, Hyungjin M, Terrell J, March L, Dawson L, Ship JA (2001) Xerostomia and its predictors following parotid-sparing irradiation of head and neck cancer. Head Neck 50:695–704
8.
Zurück zum Zitat Little M, Schipper M, Feng FY, Vineberg K, Cornwall C, Murdoch-Kinch AC, Eisbruch A (2012) Reducing xerostomia after chemo-IMRT for head and neck cancer: beyond sparing the parotid glands. Int J Radiat Oncol Biol Phys 83:1007–1014CrossRefPubMed Little M, Schipper M, Feng FY, Vineberg K, Cornwall C, Murdoch-Kinch AC, Eisbruch A (2012) Reducing xerostomia after chemo-IMRT for head and neck cancer: beyond sparing the parotid glands. Int J Radiat Oncol Biol Phys 83:1007–1014CrossRefPubMed
9.
Zurück zum Zitat Heutte N, Plisson L, Lange M, Prevost V, Babin E (2014) Quality of life tools in head and neck oncology. Eur Ann Otorhinolaryngol Head Neck Dis 131:33–47CrossRefPubMed Heutte N, Plisson L, Lange M, Prevost V, Babin E (2014) Quality of life tools in head and neck oncology. Eur Ann Otorhinolaryngol Head Neck Dis 131:33–47CrossRefPubMed
10.
Zurück zum Zitat Meirovitz A, Murdoch-Kinch CA, Schipper M, Pan C, Eisbruch A (2006) Grading xerostomia by physicians or by patients after intensity-modulated radiotherapy of head-and-neck cancer. Int J Radiat Oncol 60(2):445–453CrossRef Meirovitz A, Murdoch-Kinch CA, Schipper M, Pan C, Eisbruch A (2006) Grading xerostomia by physicians or by patients after intensity-modulated radiotherapy of head-and-neck cancer. Int J Radiat Oncol 60(2):445–453CrossRef
11.
Zurück zum Zitat Eisbruch A, Rhodus N, Rosenthal D, Murphy B, Rasch C, Sonis S, Scarantino C, Brizel D (2003) How should we measure and report radiotherapy-induced xerostomia? Semin Radiat Oncol 13:226–234CrossRefPubMed Eisbruch A, Rhodus N, Rosenthal D, Murphy B, Rasch C, Sonis S, Scarantino C, Brizel D (2003) How should we measure and report radiotherapy-induced xerostomia? Semin Radiat Oncol 13:226–234CrossRefPubMed
12.
Zurück zum Zitat Fox PC, Busch KA, Baum BJ (1987) Subjective reports of xerostomia and objective measures of salivary gland performance. J Am Dent Assoc 115:581–584CrossRefPubMed Fox PC, Busch KA, Baum BJ (1987) Subjective reports of xerostomia and objective measures of salivary gland performance. J Am Dent Assoc 115:581–584CrossRefPubMed
13.
Zurück zum Zitat Thomas J, Nelson J (2003) Research Methods in Physical Activity. 3th ed. (editor of translation: karteroliotis k). Athens, Greece: Medical Publications Paschalidis. Thomas J, Nelson J (2003) Research Methods in Physical Activity. 3th ed. (editor of translation: karteroliotis k). Athens, Greece: Medical Publications Paschalidis.
14.
Zurück zum Zitat Henson RK, Roberts JK (2006) Use of exploratory factor analysis in published research: common errors and some comment on improved practice. Educ Psychol Meas 66:393–416CrossRef Henson RK, Roberts JK (2006) Use of exploratory factor analysis in published research: common errors and some comment on improved practice. Educ Psychol Meas 66:393–416CrossRef
15.
Zurück zum Zitat Miah AB, Gulliford SL, Morden J, Newbold KL, Bhide SA, Zaidi SH, Hall E, Harrington KJ, Nutting CM (2016) Recovery of Salivary Function: Contralateral Parotid-sparing Intensity-modulated Radiotherapy versus Bilateral Superficial Lobe Parotid-sparing Intensity-modulated Radiotherapy. Clin Oncol (R Coll Radiol).(in press) Miah AB, Gulliford SL, Morden J, Newbold KL, Bhide SA, Zaidi SH, Hall E, Harrington KJ, Nutting CM (2016) Recovery of Salivary Function: Contralateral Parotid-sparing Intensity-modulated Radiotherapy versus Bilateral Superficial Lobe Parotid-sparing Intensity-modulated Radiotherapy. Clin Oncol (R Coll Radiol).(in press)
16.
Zurück zum Zitat Pacholke HD, Amdur RJ, Morris CG, Li JG, Dempsey JF, Hinerman RW, Mendenhall WM (2005) Late xerostomia after intensity modulated radiation therapy versus conventional radiotherapy. Am J Clin Oncol 28:351–358CrossRefPubMed Pacholke HD, Amdur RJ, Morris CG, Li JG, Dempsey JF, Hinerman RW, Mendenhall WM (2005) Late xerostomia after intensity modulated radiation therapy versus conventional radiotherapy. Am J Clin Oncol 28:351–358CrossRefPubMed
17.
Zurück zum Zitat Jabbari S, Kim HM, Feng M, Lin A, Tsien C, Elshaikh M, Terrel E, Murdoch-Kinch C, Eisbruch A (2005) Matched case-control study of quality of life and xerostomia after intensity-modulated radiotherapy or standard radiotherapy for head-and-neck cancer: initial report. Int J Radiat Oncol 63:725–731CrossRef Jabbari S, Kim HM, Feng M, Lin A, Tsien C, Elshaikh M, Terrel E, Murdoch-Kinch C, Eisbruch A (2005) Matched case-control study of quality of life and xerostomia after intensity-modulated radiotherapy or standard radiotherapy for head-and-neck cancer: initial report. Int J Radiat Oncol 63:725–731CrossRef
18.
Zurück zum Zitat Chen XL, Qiu ZW, Gu MF, Su Y, Liu LZ, Liu Y, Mo CW, Xu Q, Sun J, Li DH (2014) Translation and validation of the Chinese version of the quality of life radiation therapy instrument and the head & neck module (QOL-RTI/H&N). Health Qual Life Outcomes 12:51CrossRefPubMedPubMedCentral Chen XL, Qiu ZW, Gu MF, Su Y, Liu LZ, Liu Y, Mo CW, Xu Q, Sun J, Li DH (2014) Translation and validation of the Chinese version of the quality of life radiation therapy instrument and the head & neck module (QOL-RTI/H&N). Health Qual Life Outcomes 12:51CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Franzen L, Funegard U, Ericson T, Henriksson R (1992) Parotid gland function during and following radiotherapy of malignancies in the head and neck. Eur J Cancer 28:457–462CrossRefPubMed Franzen L, Funegard U, Ericson T, Henriksson R (1992) Parotid gland function during and following radiotherapy of malignancies in the head and neck. Eur J Cancer 28:457–462CrossRefPubMed
20.
Zurück zum Zitat Citak E, Tulek Z (2013) Longitudinal quality of life in Turkish patients with head and neck cancer undergoing radiotherapy. Support Care Cancer 21:2171–2183CrossRefPubMed Citak E, Tulek Z (2013) Longitudinal quality of life in Turkish patients with head and neck cancer undergoing radiotherapy. Support Care Cancer 21:2171–2183CrossRefPubMed
Metadaten
Titel
Validity and reliability of the Greek version of the xerostomia questionnaire in head and neck cancer patients
verfasst von
Pinelopi Theopisti Memtsa
Maria Tolia
Ioannis Tzitzikas
Ioannis Bizakis
Kyriaki Pistevou-Gombaki
Martha Charalambidou
Chrysoula Iliopoulou
George Kyrgias
Publikationsdatum
31.10.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 3/2017
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-016-3471-0

Weitere Artikel der Ausgabe 3/2017

Supportive Care in Cancer 3/2017 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.