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01.12.2016 | Research | Ausgabe 1/2016 Open Access

Perioperative Medicine 1/2016

Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients

Zeitschrift:
Perioperative Medicine > Ausgabe 1/2016
Autoren:
Sarka Moravcova, Bonnie Kyle, Hilary Shanahan, Savvas Giannaris, Andrew Smith, Colin Hamilton-Davies
Wichtige Hinweise
The work was carried out at the Department of Anaesthesia & Critical Care, University College London Hospitals NHS Foundation Trust, 235 Euston Road, London NW1 2BU.

Abstract

Background

Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery.

Methods

We examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery.

Results

Pre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers.

Conclusions

The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.
Literatur
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