nach oben

Erschienen in:

08.11.2016 | Neurology and Preclinical Neurological Studies - Short communication

Vasomotor regulation in patients with multiple system atrophy

Erschienen in: Journal of Neural Transmission | Ausgabe 4/2017

Einloggen, um Zugang zu erhalten

Abstract

To investigate the vasomotor regulation in multiple system atrophy (MSA), we simultaneously recorded muscle sympathetic nerve activity (MSNA), heart rate, and blood pressure in 14 MSA patients without syncope and 18 healthy subjects. Resting MSNA bursts were significantly less frequent in MSA patients than healthy subjects (p < 0.001), while the increase of MSNA bursts with head-up tilt was significantly greater in MSA patients (p < 0.01). In patients with MSA, orthostatic hypotension may be prevented by an augmented MSNA response.

Donadio V, Cortelli P, Elam M, Di Stasi V, Montagna P, Holmberg B, Giannoccaro MP, Bugiardini E, Avoni P, Liguori R (2010) Autonomic innervation in multiple system atrophy and pure autonomic failure. J Neurol Neurosurg Psychiatry 81:1327–1335CrossRefPubMed

Hakusui S, Sugiyama Y, Iwase S, Hasegawa Y, Koike Y, Mano T, Takahashi A (1991) Postprandial hypotension: microneurographic analysis and treatment with vasopressin. Neurology 41:712–715CrossRefPubMed

Kachi T, Iwase S, Mano T, Saito M, Kunimoto M, Sobue G (1988) Effect of L-threo-3, 4-dihydroxyphenylserine on muscle sympathetic nerve activities in Shy-Drager syndrome. Neurology 38:1091–1094CrossRefPubMed

Köllensperger M, Geser F, Ndayisaba J-P, Boesch S, Seppi K, Ostergaard K, Dupont E, Cardozo A, Tolosa K, Abele M, Klockgether T, Yekhlef F, Tison F, Daniels C, Wenning GK (2010) Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European Multiple System Atrophy registry. Mov Disord 25:2604–2612CrossRefPubMed

Kunimoto M (2001) Sympathetic nerve activity in multiple system atrophy. Auton Nerv Syst 38:221–225 (in Japanese)

Lipp A, Sandroni P, Ahlskog JE, Fealey RD, Kimpinski K, Iodice V, Gehrking TL, Weigand SD, Sletten DM, Gehrking JA, Nickander KK, Singer W, Maragamore DM, Gilman S, Wenning GK, Shults CW, Low PA (2009) Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure. Arch Neurol 66:742–750CrossRefPubMedPubMedCentral

Magalhaes M, Wenning GK, Daniel SE, Quinn NP (1995) Autonomic dysfunction in pathologically confirmed multiple system atrophy and idiopathic Parkinson’s disease–a retrospective comparison. Acta Neurol Scand 91:98–102CrossRefPubMed

Mano T, Iwase S, Toma S (2006) Microneurography as a tool in clinical neurophysiology to investigate peripheral neural traffic in humans. Clin Neurophysiol 117:2357–2384CrossRefPubMed

Sandroni P, Ahlskog JE, Fealey RD, Low PA (1991) Autonomic involvement in extrapyramidal and cerebellar disorders. Clin Auton Res 1:147–155CrossRefPubMed

Shindo K, Watanabe H, Tanaka H, Ohashi K, Nagasaka T, Tsunoda S, Shiozawa Z (2003) Age and duration related changes in muscle sympathetic nerve activity in Parkinson’s disease. J Neurol Neurosurg Psychiatry 74:1407–1411CrossRefPubMedPubMedCentral

Tada M, Onodera O, Tada M, Ozawa T, Piao Y-S, Kakita A, Takahashi H, Nshizawa M (2007) Early development of autonomic dysfunction may predict poor prognosis in patients with multiple system atrophy. Arch Neurol 64:256–260CrossRefPubMed

Watanabe H, Saito Y, Terao S, Ando T, Kachi T, Mukai E, Aiba I, Abe Y, Tamakosi A, Doyu M, Hirayama M, Sobue G (2002) Progression and prognosis in multiple system atrophy. An analysis of 230 Japanese patients. Brain 125:1070–1083CrossRefPubMed

Wenning GK, Tison F, Shlomo B, Daniel SE, Quinn NP (1997) Multiple system atrophy: a review of 203 pathologically proven cases. Mov Disord 12:133–147CrossRefPubMed

Yabe I, Soma H, Takei A, Fujiki N, Yanagihara T, Sasaki H (2006) MSA-C is the predominant clinical phenotype of MSA in Japan: analysis of 142 patients with probable MSA. J Neurol Sci 249:115–121CrossRefPubMed

Titel: Vasomotor regulation in patients with multiple system atrophy
Publikationsdatum: 08.11.2016
Erschienen in: Journal of Neural Transmission / Ausgabe 4/2017
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-016-1644-0

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

18.04.2024 | Arterielle Hypertonie | Nachrichten

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Vasomotor regulation in patients with multiple system atrophy

Abstract

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

Manche Gestagene können das Risiko für Meningeome erhöhen

Parkinson: Größere Studie bestätigt Genauigkeit von Hauttest

Update Neurologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2017

Mutation screening of PLA2G6 in Japanese patients with early onset dystonia-parkinsonism

Postural control is associated with cognition and fear of falling in patients with multiple sclerosis

Age-dependent alpha-synuclein accumulation is correlated with elevation of mitochondrial TRPC3 in the brains of monkeys and mice

An exploratory cohort study of sensory extinction in acute stroke: prevalence, risk factors, and time course

Safety of botulinum toxin short interval therapy using incobotulinumtoxin A

Differential behavioral outcomes following neonatal versus fetal human retinal pigment epithelial cell striatal implants in parkinsonian rats

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

Manche Gestagene können das Risiko für Meningeome erhöhen

Parkinson: Größere Studie bestätigt Genauigkeit von Hauttest

Update Neurologie