23.11.2023
Ventricular arrhythmias prior to continuous flow left ventricular assist device implantation were not associated with reduced 1-year mortality: a single-center experience
verfasst von:
Summit Pandat, Peter Rothstein, Rachel Laird, Momin Islam, Syed Zaid, Amy Truman, Arvind Bhimaraj, Rayan Yousefzai, Ashrith Guha, Paul Schurmann, Amish Dave, Miguel Valderrábano, Nilesh Mathuria
Erschienen in:
Journal of Interventional Cardiac Electrophysiology
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Ausgabe 4/2024
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Excerpt
Continuous flow left ventricular assist devices (CF-LVADs) have become a mainstay of therapy for end-stage heart failure as either bridge to transplant or destination therapy [
1]. Although the incidence and prognostic role of ventricular arrhythmias (VA) after CF-LVAD have been studied, there is less clear evidence regarding the prognostic role of VA prior to CF-LVAD. Prior studies have suggested pre-implant VA are associated with increased post-implant VA and implantable cardioverter-defibrillator (ICD) shocks without increased mortality, while early VA post-implant is associated with increased mortality predicted by pre-implant ventricular tachycardia (VT) storm [
2,
3]. Given the conflicting data and relatively small datasets, institutional practices differ substantially for patients with VA and CF-LVAD candidacy. Here we report single-center outcomes on the association between pre-implant VA and post-implant survival. Additionally, we report the relationship between escalating antiarrhythmic drug (AAD) therapy prior to CF-LVAD and its impact on post-implant ICD therapies and survival. …