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Erschienen in: International Ophthalmology 11/2019

13.04.2019 | Original Paper

Very late-onset flap margin corneal ulcer following laser in situ keratomileusis

verfasst von: Gilad Rabina, Nur Azem, Michael Mimouni, Idan Hecht, David Varssano

Erschienen in: International Ophthalmology | Ausgabe 11/2019

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Abstract

Purpose

To report and characterize cases of very late onset (5 years or more after surgery) flap margin corneal ulcers after laser in situ keratomileusis (LASIK) procedure.

Methods

A retrospective case series of consecutive patients who were diagnosed with very late flap margin corneal ulcers following LASIK, between January 2014 and July 2017. All patients were treated with topical antibiotics and were followed up until complete resolution.

Results

A total of eight patients, with a mean age of 46.5 ± 11 years, (range 31–64 years), were included in this study. All patients underwent uneventful myopic LASIK 13.3 ± 3 (range 10–20) years before presentation. Patients best corrected visual acuity (BCVA) at presentation was 0.20 ± 0.15 logMAR compared to a final BCVA of 0.10 ± 0.10 logMAR (p = 0.28). The ulcer was located in the bottom two clock hours of the flap margin (5–7 o’clock) in six (75%) patients and superior (11 o’clock) in the remaining two patients (p = 0.048). Seven patients (87.5%) suffered from blepharitis, and only one did not.

Conclusions

LASIK may be associated with an increased risk of late-onset corneal ulcer occurring years after the procedure. Instability of the flap margin, blepharitis and dry eye are possible causes of epithelial disturbance and may account for this complication.
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Metadaten
Titel
Very late-onset flap margin corneal ulcer following laser in situ keratomileusis
verfasst von
Gilad Rabina
Nur Azem
Michael Mimouni
Idan Hecht
David Varssano
Publikationsdatum
13.04.2019
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 11/2019
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-019-01100-0

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