Skip to main content
Erschienen in: Surgery Today 12/2017

11.03.2017 | Review Article

Video-assisted thoracoscopic surgery node dissection for lung cancer treatment

verfasst von: Atsushi Watanabe, Masahiro Miyajima, Taijiro Mishina, Kodai Tsuruta, Yuki Takahashi, Ryunosuke Maki, Makoto Tada

Erschienen in: Surgery Today | Ausgabe 12/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Mediastinal node dissection (MND) is an integral component of the surgical treatment for non-small cell lung cancer (NSCLC). Although video-assisted thoracoscopic surgery (VATS) has been used increasingly for lung cancer treatment, the accuracy of by VATS MND still remains controversial. We reviewed the surgical results of VATS MND for NSCLC.

Methods

A systematic review of literature was performed, and articles that fully described the surgical procedure, devices, and results of VATS MND were selected to compare the efficacy of MND by VATS and thoracotomy.

Results

Various techniques and equipments have been shown to perform adequate MND, but there is an argument as to the method of estimation of the accuracy of MND. Most of the recent studies showed that the nodal upstaging and number of dissected nodes are significantly lower by VATS than after thoracotomy. Oppositely, some studies showed VATS noninferiority in these issues. Complications such as chylothorax, pleural effusion, bleeding, and nerve damage were similar in both groups.

Conclusions

Although ND by VATS remains controversial, VATS MND is becoming easier and more feasible owing to the development of more advanced endoscopic cameras and equipments. We should learn further to become more adept at performing adequate ND by VATS.
Literatur
1.
Zurück zum Zitat McKenna RJ Jr, Houck W, Fuller CB. Video-assisted thoracic surgery lobectomy: experience with 1,100 cases. Ann Thorac Surg. 2016;81:421–6.CrossRef McKenna RJ Jr, Houck W, Fuller CB. Video-assisted thoracic surgery lobectomy: experience with 1,100 cases. Ann Thorac Surg. 2016;81:421–6.CrossRef
2.
Zurück zum Zitat Licht PB, Jørgensen OD, Ladegaard L, Jakobsen E. A national study of nodal upstaging after thoracoscopic versus open lobectomy for clinical stage I lung cancer. Ann Thorac Surg. 2013;96:943–50.CrossRefPubMed Licht PB, Jørgensen OD, Ladegaard L, Jakobsen E. A national study of nodal upstaging after thoracoscopic versus open lobectomy for clinical stage I lung cancer. Ann Thorac Surg. 2013;96:943–50.CrossRefPubMed
3.
Zurück zum Zitat Scott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, et al. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovas Surg. 2010;139:976–83.CrossRef Scott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, et al. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovas Surg. 2010;139:976–83.CrossRef
4.
Zurück zum Zitat Scott WJ, Matteotti RS, Egleston BL, Oseni S, Flaherty JF. A comparison of perioperative outcomes of video-assisted thoracic surgical (VATS) lobectomy with open thoracotomy and lobectomy: results of an analysis using propensity score based weighting. Ann Surg Innov Res. 2010;4:1.CrossRefPubMedPubMedCentral Scott WJ, Matteotti RS, Egleston BL, Oseni S, Flaherty JF. A comparison of perioperative outcomes of video-assisted thoracic surgical (VATS) lobectomy with open thoracotomy and lobectomy: results of an analysis using propensity score based weighting. Ann Surg Innov Res. 2010;4:1.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Lardinois D, De Leyn P, Van Schil P, Porta RR, Waller D, Passlick B, et al. ESTS guidelines for intraoperative lymph node staging in non-small cell lung cancer. Eur J Cardiothorac Surg. 2006;30:787–92.CrossRefPubMed Lardinois D, De Leyn P, Van Schil P, Porta RR, Waller D, Passlick B, et al. ESTS guidelines for intraoperative lymph node staging in non-small cell lung cancer. Eur J Cardiothorac Surg. 2006;30:787–92.CrossRefPubMed
6.
Zurück zum Zitat Howington JA, Blum MG, Chang AC, Balekian AA, Murthy SC. Treatment of stage I and II non-small cell lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143:e278S–e313S.CrossRefPubMed Howington JA, Blum MG, Chang AC, Balekian AA, Murthy SC. Treatment of stage I and II non-small cell lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143:e278S–e313S.CrossRefPubMed
7.
Zurück zum Zitat D’Amico TA. Videothoracoscopic mediastinal lymphadenectomy. Thorac Surg Clin. 2010;20:207–13.CrossRefPubMed D’Amico TA. Videothoracoscopic mediastinal lymphadenectomy. Thorac Surg Clin. 2010;20:207–13.CrossRefPubMed
8.
Zurück zum Zitat De Giacomo T, Venuta F, Rendina EA. Role of lymphadenectomy in the treatment of clinical stage I non-small cell lung cancer. Thorac Surg Clin. 2007;17:217–21.CrossRefPubMed De Giacomo T, Venuta F, Rendina EA. Role of lymphadenectomy in the treatment of clinical stage I non-small cell lung cancer. Thorac Surg Clin. 2007;17:217–21.CrossRefPubMed
9.
Zurück zum Zitat De Leyn P, Lardinois D, Van Schil P, Rami-Porta R, Passlick B, Zielinski M, et al. ESTS. European trends in preoperative and intraoperative nodal staging: ESTS guidelines. J Thorac Oncol. 2007;2:357–61.CrossRefPubMed De Leyn P, Lardinois D, Van Schil P, Rami-Porta R, Passlick B, Zielinski M, et al. ESTS. European trends in preoperative and intraoperative nodal staging: ESTS guidelines. J Thorac Oncol. 2007;2:357–61.CrossRefPubMed
10.
Zurück zum Zitat Amer K, Khan A-Z, Singh N, Addis B, Jogai S, Harden S, et al. Video-assisted thoracic surgery systematic mediastinal nodal dissection and stage migration: impact on clinical pathway. Eur J Cardiothorac Surg. 2011;40:1474–81.PubMed Amer K, Khan A-Z, Singh N, Addis B, Jogai S, Harden S, et al. Video-assisted thoracic surgery systematic mediastinal nodal dissection and stage migration: impact on clinical pathway. Eur J Cardiothorac Surg. 2011;40:1474–81.PubMed
11.
Zurück zum Zitat Watanabe A, Nakazawa J, Miyajima M, Harada R, Nakashima S, Mawatari T, et al. Thoracoscopic mediastinal lymph node dissection for lung cancer. Semin Thorac Cardiovasc Surg. 2012;24:68–73.CrossRefPubMed Watanabe A, Nakazawa J, Miyajima M, Harada R, Nakashima S, Mawatari T, et al. Thoracoscopic mediastinal lymph node dissection for lung cancer. Semin Thorac Cardiovasc Surg. 2012;24:68–73.CrossRefPubMed
13.
Zurück zum Zitat Baste JM, Haddad L, Melki J, Peillon C. Anterior subcarinal node dissection on the left side using video thoracoscopy: an easier technique. Ann Thorac Surg. 2015;99:e99–e100.CrossRefPubMed Baste JM, Haddad L, Melki J, Peillon C. Anterior subcarinal node dissection on the left side using video thoracoscopy: an easier technique. Ann Thorac Surg. 2015;99:e99–e100.CrossRefPubMed
14.
Zurück zum Zitat Witte B, Messerschmidt A, Hillebrand H, Gross S, Wolf M, Kriegel E, et al. Combined videothoracoscopic and videomediastinoscopic approach improves radicality of minimally invasive mediastinal lymphadenectomy for early stage lung carcinoma. Eur J Cardiothorac Surg. 2009;35:343–7.CrossRefPubMed Witte B, Messerschmidt A, Hillebrand H, Gross S, Wolf M, Kriegel E, et al. Combined videothoracoscopic and videomediastinoscopic approach improves radicality of minimally invasive mediastinal lymphadenectomy for early stage lung carcinoma. Eur J Cardiothorac Surg. 2009;35:343–7.CrossRefPubMed
15.
Zurück zum Zitat Lin Z, Xu S, Wang Q. Uniportal video-assisted thoracoscopic surgery right upper lobectomy with systematic lymphadenectomy in a semiprone position. J Thorac Dis. 2014;6:1840–2.PubMedPubMedCentral Lin Z, Xu S, Wang Q. Uniportal video-assisted thoracoscopic surgery right upper lobectomy with systematic lymphadenectomy in a semiprone position. J Thorac Dis. 2014;6:1840–2.PubMedPubMedCentral
16.
Zurück zum Zitat Lin Z, Xi J, Xu S, Jiang W, Wang L, Wang Q. Uniportal video-assisted thoracic surgery lobectomy in semiprone position: primary experience of 105 cases. J Thorac Dis. 2015;7:2389–95.PubMedPubMedCentral Lin Z, Xi J, Xu S, Jiang W, Wang L, Wang Q. Uniportal video-assisted thoracic surgery lobectomy in semiprone position: primary experience of 105 cases. J Thorac Dis. 2015;7:2389–95.PubMedPubMedCentral
17.
Zurück zum Zitat Akiba T, Marushima H, Hirano K, Morikawa T. Thoracoscopic mediastinal lymph node dissection using an endoscopic spacer. Ann Thorac Cardiovasc Surg. 2012;18:281–3.CrossRefPubMed Akiba T, Marushima H, Hirano K, Morikawa T. Thoracoscopic mediastinal lymph node dissection using an endoscopic spacer. Ann Thorac Cardiovasc Surg. 2012;18:281–3.CrossRefPubMed
18.
Zurück zum Zitat Hirai K, Ibi T, Bessho R, Koizumi K, Shimizu K. Use of the “Secrea (Hogy™)” sponge spacer in thoracoscopic surgery for lung cancer. J Surg Oncol. 2011;104:857–8.CrossRefPubMed Hirai K, Ibi T, Bessho R, Koizumi K, Shimizu K. Use of the “Secrea (Hogy™)” sponge spacer in thoracoscopic surgery for lung cancer. J Surg Oncol. 2011;104:857–8.CrossRefPubMed
19.
Zurück zum Zitat Sato Y, Tezuka Y, Kanai Y, Otani S, Yamamoto S, Tetsuka K, et al. Novel retractor for lymph node dissection by video-assisted thoracic surgery. Ann Thorac Surg. 2008;8:1036–7.CrossRef Sato Y, Tezuka Y, Kanai Y, Otani S, Yamamoto S, Tetsuka K, et al. Novel retractor for lymph node dissection by video-assisted thoracic surgery. Ann Thorac Surg. 2008;8:1036–7.CrossRef
20.
Zurück zum Zitat Sagawa M, Sato M, Sakurada A, Matsumura Y, Endo C, Handa M, Kondo T. A prospective trial of systematic nodal dissection for lung cancer by video-assisted thoracic surgery: can it be perfect? Ann Thorac Surg. 2002;73:900–4.CrossRefPubMed Sagawa M, Sato M, Sakurada A, Matsumura Y, Endo C, Handa M, Kondo T. A prospective trial of systematic nodal dissection for lung cancer by video-assisted thoracic surgery: can it be perfect? Ann Thorac Surg. 2002;73:900–4.CrossRefPubMed
21.
Zurück zum Zitat Watanabe A, Koyanagi T, Ohsawa H, Mawatari T, Nakashima S, Takahashi N, et al. Systematic node dissection by VATS is not inferior to that through an open thoracotomy: a comparative clinicopathologic retrospective study. Surgery. 2005;1383:510–7.CrossRef Watanabe A, Koyanagi T, Ohsawa H, Mawatari T, Nakashima S, Takahashi N, et al. Systematic node dissection by VATS is not inferior to that through an open thoracotomy: a comparative clinicopathologic retrospective study. Surgery. 2005;1383:510–7.CrossRef
22.
Zurück zum Zitat D’Amico TA, Niland J, Mamet R, Zornosa C, Dexter EU, Onaitis MW. Efficacy of mediastinal lymph node dissection during lobectomy for lung cancer by thoracoscopy and thoracotomy. Ann Thorac Surg. 2011;92:226–31.CrossRefPubMed D’Amico TA, Niland J, Mamet R, Zornosa C, Dexter EU, Onaitis MW. Efficacy of mediastinal lymph node dissection during lobectomy for lung cancer by thoracoscopy and thoracotomy. Ann Thorac Surg. 2011;92:226–31.CrossRefPubMed
23.
Zurück zum Zitat Palade E, Passlick B, Osei-Agyemang T, Günter J, Wiesemann S. Video-assisted vs. open mediastinal lymphadenectomy for stage I non-small-cell lung cancer: results of a prospective randomized trial. Eur J Cardiothorac Surg. 2013;44:244–9.CrossRefPubMed Palade E, Passlick B, Osei-Agyemang T, Günter J, Wiesemann S. Video-assisted vs. open mediastinal lymphadenectomy for stage I non-small-cell lung cancer: results of a prospective randomized trial. Eur J Cardiothorac Surg. 2013;44:244–9.CrossRefPubMed
24.
Zurück zum Zitat Amer K, Khan AZ, Singh N, Addis B, Jogai S, Harden S, et al. Video-assisted thoracic surgery systematic mediastinal nodal dissection and stage migration: impact on clinical pathway. Eur J Cardiothorac Surg. 2011;406:1474–81. Amer K, Khan AZ, Singh N, Addis B, Jogai S, Harden S, et al. Video-assisted thoracic surgery systematic mediastinal nodal dissection and stage migration: impact on clinical pathway. Eur J Cardiothorac Surg. 2011;406:1474–81.
25.
Zurück zum Zitat Martin JT, Durbin EB, Chen L, Gal T, Mahan A, Ferraris V, et al. Nodal upstaging during lung cancer resection is associated with surgical approach. Ann Thorac Surg. 2016;101:238–445.CrossRefPubMed Martin JT, Durbin EB, Chen L, Gal T, Mahan A, Ferraris V, et al. Nodal upstaging during lung cancer resection is associated with surgical approach. Ann Thorac Surg. 2016;101:238–445.CrossRefPubMed
26.
Zurück zum Zitat Kocher F, Ng C, Augustin F. On the article “Nodal upstaging is more common with thoracotomy than with VATS during lobectomy for early-stage lung cancer: an analysis from the National Cancer Data Base” by Medbery et al. J Thorac Oncol. 2016;11:e103–4.CrossRefPubMed Kocher F, Ng C, Augustin F. On the article “Nodal upstaging is more common with thoracotomy than with VATS during lobectomy for early-stage lung cancer: an analysis from the National Cancer Data Base” by Medbery et al. J Thorac Oncol. 2016;11:e103–4.CrossRefPubMed
27.
Zurück zum Zitat Scott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, et al. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovasc Surg. 2010;139:976–83.CrossRefPubMed Scott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, et al. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovasc Surg. 2010;139:976–83.CrossRefPubMed
28.
Zurück zum Zitat Medbery RL, Gillespie TW, Liu Y, Nickleach DC, Lipscomb J, Sancheti MS, et al. Nodal upstaging is more common with thoracotomy than with VATS during lobectomy for early-stage lung cancer: an analysis from the National Cancer Data Base. J Thorac Oncol. 2016;11:222–33.CrossRefPubMedPubMedCentral Medbery RL, Gillespie TW, Liu Y, Nickleach DC, Lipscomb J, Sancheti MS, et al. Nodal upstaging is more common with thoracotomy than with VATS during lobectomy for early-stage lung cancer: an analysis from the National Cancer Data Base. J Thorac Oncol. 2016;11:222–33.CrossRefPubMedPubMedCentral
29.
Zurück zum Zitat Wang W, Yin W, Shao W, Jiang G, Wang Q, Liu L, et al. Comparative study of systematic thoracoscopic lymphadenectomy and conventional thoracotomy in resectable non-small cell lung cancer. J Thorac Dis. 2014;6:45–51.PubMedPubMedCentral Wang W, Yin W, Shao W, Jiang G, Wang Q, Liu L, et al. Comparative study of systematic thoracoscopic lymphadenectomy and conventional thoracotomy in resectable non-small cell lung cancer. J Thorac Dis. 2014;6:45–51.PubMedPubMedCentral
30.
Zurück zum Zitat Whitson BA, Andrade RS, Boettcher A, Bardales R, Kratzke RA, Dahlberg PS, et al. Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small cell lung cancer. Ann Thorac Surg. 2007;83:1965–70.CrossRefPubMed Whitson BA, Andrade RS, Boettcher A, Bardales R, Kratzke RA, Dahlberg PS, et al. Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small cell lung cancer. Ann Thorac Surg. 2007;83:1965–70.CrossRefPubMed
31.
Zurück zum Zitat Denlinger CE, Fernandez F, Meyers BF, Pratt W, Zoole JB, Patterson GA, et al. Lymph node evaluation in video-assisted thoracoscopic lobectomy versus lobectomy by thoracotomy. Ann Thorac Surg. 2010;89:1730–6.CrossRefPubMed Denlinger CE, Fernandez F, Meyers BF, Pratt W, Zoole JB, Patterson GA, et al. Lymph node evaluation in video-assisted thoracoscopic lobectomy versus lobectomy by thoracotomy. Ann Thorac Surg. 2010;89:1730–6.CrossRefPubMed
32.
Zurück zum Zitat Boffa DJ, Kosinski AS, Paul S, Mitchell JD, Onaitis M. Lymph node evaluation by open or video-assisted approaches in 11,500 anatomic lung cancer resections. Ann Thorac Surg. 2012;94:347–53.CrossRefPubMed Boffa DJ, Kosinski AS, Paul S, Mitchell JD, Onaitis M. Lymph node evaluation by open or video-assisted approaches in 11,500 anatomic lung cancer resections. Ann Thorac Surg. 2012;94:347–53.CrossRefPubMed
33.
Zurück zum Zitat Merritt RE, Hoang CD, Shrager JB. Lymph node evaluation achieved by open lobectomy compared with thoracoscopic lobectomy for N0 lung cancer. Ann Thorac Surg. 2013;96:117–7.CrossRef Merritt RE, Hoang CD, Shrager JB. Lymph node evaluation achieved by open lobectomy compared with thoracoscopic lobectomy for N0 lung cancer. Ann Thorac Surg. 2013;96:117–7.CrossRef
34.
Zurück zum Zitat Kim K, Kim HK, Park JS, Chang SW, Choi YS, Kim J, et al. Video-assisted thoracic surgery lobectomy: single institutional experience with 704 cases. Ann Thorac Surg. 2010;89:S2118–22.CrossRefPubMed Kim K, Kim HK, Park JS, Chang SW, Choi YS, Kim J, et al. Video-assisted thoracic surgery lobectomy: single institutional experience with 704 cases. Ann Thorac Surg. 2010;89:S2118–22.CrossRefPubMed
35.
Zurück zum Zitat Cerfolio RJ, Bryant AS, Minnich DJ. Complete thoracic mediastinal lymphadenectomy leads to a higher rate of pathologically proven N2 disease in patients with non-small cell lung cancer. Ann Thorac Surg. 2012;94:902–6.CrossRefPubMed Cerfolio RJ, Bryant AS, Minnich DJ. Complete thoracic mediastinal lymphadenectomy leads to a higher rate of pathologically proven N2 disease in patients with non-small cell lung cancer. Ann Thorac Surg. 2012;94:902–6.CrossRefPubMed
36.
Zurück zum Zitat Ratto G, Ratto GB, Costa R, Maineri P, Alloisio A, Bruzzi P, et al. Is there a subset of patients with preoperatively diagnosed N2 non-small cell lung cancer who might benefit from surgical resection? J Thorac Cardiovasc Surg. 2009;138:849–58.CrossRefPubMed Ratto G, Ratto GB, Costa R, Maineri P, Alloisio A, Bruzzi P, et al. Is there a subset of patients with preoperatively diagnosed N2 non-small cell lung cancer who might benefit from surgical resection? J Thorac Cardiovasc Surg. 2009;138:849–58.CrossRefPubMed
37.
Zurück zum Zitat Watanabe A, Mishina T, Ohori S, Koyanagi T, Nakashima S, Mawatari T, et al. Is video-assisted thoracoscopic surgery a feasible approach for clinical N0 and postoperatively pathological N2 non-small cell lung cancer? Eur J Cardiothorac Surg. 2008;33:812–8.CrossRefPubMed Watanabe A, Mishina T, Ohori S, Koyanagi T, Nakashima S, Mawatari T, et al. Is video-assisted thoracoscopic surgery a feasible approach for clinical N0 and postoperatively pathological N2 non-small cell lung cancer? Eur J Cardiothorac Surg. 2008;33:812–8.CrossRefPubMed
38.
Zurück zum Zitat Zhong C, Yao F, Zhao H. Clinical outcomes of thoracoscopic lobectomy for patients with clinical N0 and pathologic N2 non-small cell lung cancer. Ann Thorac Surg. 2013;95:987–92.CrossRefPubMed Zhong C, Yao F, Zhao H. Clinical outcomes of thoracoscopic lobectomy for patients with clinical N0 and pathologic N2 non-small cell lung cancer. Ann Thorac Surg. 2013;95:987–92.CrossRefPubMed
39.
Zurück zum Zitat Katayama H, Kurokawa Y, Nakamura K, Ito H, Kanemitsu Y, Masuda N, et al. Extended Clavien–Dindo classification of surgical complications: Japan Clinical Oncology Group postoperative complications criteria. Surg Today. 2016;46:668–85.CrossRefPubMed Katayama H, Kurokawa Y, Nakamura K, Ito H, Kanemitsu Y, Masuda N, et al. Extended Clavien–Dindo classification of surgical complications: Japan Clinical Oncology Group postoperative complications criteria. Surg Today. 2016;46:668–85.CrossRefPubMed
40.
Zurück zum Zitat Muranishi Y, Sonobe M, Menju T, Aoyama A, Chen-Yoshikawa TF, et al. Atrial fibrillation after lung cancer surgery: incidence, severity, and risk factors. Surg Today. 2017;47:252–8.CrossRefPubMed Muranishi Y, Sonobe M, Menju T, Aoyama A, Chen-Yoshikawa TF, et al. Atrial fibrillation after lung cancer surgery: incidence, severity, and risk factors. Surg Today. 2017;47:252–8.CrossRefPubMed
41.
Zurück zum Zitat Kanzaki R, Inoue M, Minami M, Shintani Y, Funaki S, Kawamura T, et al. Outcomes of lung cancer surgery in patients with coronary artery disease: a decade of experience at a single institution. Surg Today. 2017;47:27–34.CrossRefPubMed Kanzaki R, Inoue M, Minami M, Shintani Y, Funaki S, Kawamura T, et al. Outcomes of lung cancer surgery in patients with coronary artery disease: a decade of experience at a single institution. Surg Today. 2017;47:27–34.CrossRefPubMed
42.
Zurück zum Zitat Liu CY, Hsu PK, Huang CS, Sun YH, Wu YC, Hsu WH. Chylothorax complicating video-assisted thoracoscopic surgery for non-small cell lung cancer. World J Surg. 2014;38:2875–81.CrossRefPubMed Liu CY, Hsu PK, Huang CS, Sun YH, Wu YC, Hsu WH. Chylothorax complicating video-assisted thoracoscopic surgery for non-small cell lung cancer. World J Surg. 2014;38:2875–81.CrossRefPubMed
43.
Zurück zum Zitat Paul S, Sedrakyan A, Chiu YL, Nasar A, Port JL, Lee PC, et al. Outcomes after lobectomy using thoracoscopy vs. thoracotomy: a comparative effectiveness analysis utilizing the Nationwide Inpatient Sample database. Eur J Cardiothorac Surg. 2013;43:813–7.CrossRefPubMed Paul S, Sedrakyan A, Chiu YL, Nasar A, Port JL, Lee PC, et al. Outcomes after lobectomy using thoracoscopy vs. thoracotomy: a comparative effectiveness analysis utilizing the Nationwide Inpatient Sample database. Eur J Cardiothorac Surg. 2013;43:813–7.CrossRefPubMed
44.
Zurück zum Zitat Gharagozloo F, Tempesta B, Margolis M, Alexander EP. Video-assisted thoracic surgery lobectomy for stage I lung cancer. Ann Thorac Surg. 2003;76:1009–15.CrossRefPubMed Gharagozloo F, Tempesta B, Margolis M, Alexander EP. Video-assisted thoracic surgery lobectomy for stage I lung cancer. Ann Thorac Surg. 2003;76:1009–15.CrossRefPubMed
Metadaten
Titel
Video-assisted thoracoscopic surgery node dissection for lung cancer treatment
verfasst von
Atsushi Watanabe
Masahiro Miyajima
Taijiro Mishina
Kodai Tsuruta
Yuki Takahashi
Ryunosuke Maki
Makoto Tada
Publikationsdatum
11.03.2017
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 12/2017
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-017-1494-x

Weitere Artikel der Ausgabe 12/2017

Surgery Today 12/2017 Zur Ausgabe

Leitlinien kompakt für die Allgemeinmedizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Facharzt-Training Allgemeinmedizin

Die ideale Vorbereitung zur anstehenden Prüfung mit den ersten 24 von 100 klinischen Fallbeispielen verschiedener Themenfelder

Mehr erfahren

Update Allgemeinmedizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.